Nitroglycerin
- Generic Name
- Nitroglycerin
- Brand Names
- Gonitro, Minitran, Mylan-nitro, Nitro-bid, Nitro-dur, Nitroject, Nitrolingual, Nitromist, Nitrostat, Rectiv, Trinipatch
- Drug Type
- Small Molecule
- Chemical Formula
- C3H5N3O9
- CAS Number
- 55-63-0
- Unique Ingredient Identifier
- G59M7S0WS3
- Background
Nitroglycerin, also known as glyceryl trinitrate, is an organic nitrate and a vasodilating agent that was first discovered in 1847. Originally used to dynamite, its antianginal effects were identified in the late 1860s after it produced headaches in factory workers while workers with angina pectoris or heart failure experienced relief from chest pain. Its u...
- Indication
Sublingual nitroglycerin is indicated for the acute relief of an attack or acute prophylaxis of angina pectoris due to coronary artery disease. Transdermal nitroglycerin is indicated for the prevention of angina pectoris due to coronary artery disease.
...
- Associated Conditions
- Angina Attacks, Angina Pectoris, Congestive Heart Failure (CHF), Perioperative Hypertension, Moderate to severe pain
- Associated Therapies
- -
MQX-503 vs Nitroglycerin Ointment: A Pharmacokinetic Comparison in Normal Subjects
- First Posted Date
- 2007-08-09
- Last Posted Date
- 2008-04-11
- Lead Sponsor
- MediQuest Therapeutics
- Target Recruit Count
- 6
- Registration Number
- NCT00513994
- Locations
- 🇺🇸
Charles River Clinical Services, Tacoma, Washington, United States
Microcirculation Guided Therapy Versus "Standard Treatment" of Severe Sepsis
- Conditions
- First Posted Date
- 2007-06-08
- Last Posted Date
- 2008-01-22
- Lead Sponsor
- Onze Lieve Vrouwe Gasthuis
- Target Recruit Count
- 80
- Registration Number
- NCT00484133
- Locations
- 🇳🇱
Onze Lieve Vrouwe Gasthuis, intensive care, Amsterdam, Netherlands
Dose Response Study of a Topical Formulation of Nitroglycerin for the Treatment of Raynaud's Phenomenon
- Conditions
- First Posted Date
- 2007-05-31
- Last Posted Date
- 2007-12-24
- Lead Sponsor
- MediQuest Therapeutics
- Target Recruit Count
- 15
- Registration Number
- NCT00480753
- Locations
- 🇺🇸
The Center for Rheumatology, Albany, New York, United States
Blood Pressure Interaction Between Sildenafil and Sublingual Glyceryl Trinitrate (GTN) in Men With Angina
- Conditions
- First Posted Date
- 2007-05-30
- Last Posted Date
- 2007-05-30
- Lead Sponsor
- University of Edinburgh
- Target Recruit Count
- 20
- Registration Number
- NCT00479908
- Locations
- 🇬🇧
University of Edinburgh, Edinburgh, Scotland, United Kingdom
Effect of Antioxidants on Ocular Blood Flow, Endothelial Function, and Cytokine Levels in LPS Induced Inflammatory Model in Humans.
- First Posted Date
- 2007-02-06
- Last Posted Date
- 2008-07-04
- Lead Sponsor
- Medical University of Vienna
- Target Recruit Count
- 22
- Registration Number
- NCT00431691
- Locations
- 🇦🇹
Department of Clinical Pharmacology, Medical University of Vienna, Vienna, Austria
Intravenous NTG to Preserve Gastric Microcirculation During Gastric Tube Reconstruction
- Conditions
- First Posted Date
- 2006-06-08
- Last Posted Date
- 2006-06-08
- Lead Sponsor
- Erasmus Medical Center
- Target Recruit Count
- 32
- Registration Number
- NCT00335010
- Locations
- 🇳🇱
Erasmus MC, Rotterdam, Netherlands
Intensive Blood Pressure Reduction in Acute Cerebral Haemorrhage
- Conditions
- First Posted Date
- 2005-09-26
- Last Posted Date
- 2008-06-26
- Lead Sponsor
- The George Institute
- Target Recruit Count
- 404
- Registration Number
- NCT00226096
- Locations
- 🇦🇺
Royal Prince Alfred Hospital, Sydney, New South Wales, Australia
🇦🇺Royal Adelaide Hospital, Adelaide, South Australia, Australia
🇦🇺Royal Melbourne Hospital, Melbourne, Victoria, Australia
Clevidipine in the Perioperative Treatment of Hypertension (ECLIPSE-NTG)
- First Posted Date
- 2004-10-08
- Last Posted Date
- 2014-05-06
- Lead Sponsor
- The Medicines Company
- Target Recruit Count
- 629
- Registration Number
- NCT00093886
- Locations
- 🇺🇸
Sacred Heart Health System, Pensacola, Florida, United States
🇺🇸New York University Medical Center, New York, New York, United States
🇺🇸Baptist Medical Center, South, Montgomery, Alabama, United States
Effect of Nitric Oxide Donor on Endothelial Progenitor Cells in Patients With Coronary Artery Disease
- Conditions
- First Posted Date
- 2004-08-27
- Last Posted Date
- 2008-03-04
- Target Recruit Count
- 30
- Registration Number
- NCT00090558
- Locations
- 🇺🇸
National Heart, Lung and Blood Institute (NHLBI), Bethesda, Maryland, United States
Effects of Nitric Oxide and Nitroglycerin in Patients With Sickle Cell Anemia
- Conditions
- First Posted Date
- 1999-11-04
- Last Posted Date
- 2008-03-04
- Target Recruit Count
- 58
- Registration Number
- NCT00001716
- Locations
- 🇺🇸
Warren G. Magnuson Clinical Center (CC), Bethesda, Maryland, United States
Drug Development Updates
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