Nitroglycerin
- Generic Name
- Nitroglycerin
- Brand Names
- Gonitro, Minitran, Mylan-nitro, Nitro-bid, Nitro-dur, Nitroject, Nitrolingual, Nitromist, Nitrostat, Rectiv, Trinipatch
- Drug Type
- Small Molecule
- Chemical Formula
- C3H5N3O9
- CAS Number
- 55-63-0
- Unique Ingredient Identifier
- G59M7S0WS3
- Background
Nitroglycerin, also known as glyceryl trinitrate, is an organic nitrate and a vasodilating agent that was first discovered in 1847. Originally used to dynamite, its antianginal effects were identified in the late 1860s after it produced headaches in factory workers while workers with angina pectoris or heart failure experienced relief from chest pain. Its u...
- Indication
Sublingual nitroglycerin is indicated for the acute relief of an attack or acute prophylaxis of angina pectoris due to coronary artery disease. Transdermal nitroglycerin is indicated for the prevention of angina pectoris due to coronary artery disease.
...
- Associated Conditions
- Angina Attacks, Angina Pectoris, Congestive Heart Failure (CHF), Perioperative Hypertension, Moderate to severe pain
- Associated Therapies
- -
Efficacy of Intracoronary Infusion of Different Medicine in STEMI Patients With CSFP
- Conditions
- Interventions
- First Posted Date
- 2017-09-28
- Last Posted Date
- 2020-03-12
- Lead Sponsor
- RenJi Hospital
- Target Recruit Count
- 57
- Registration Number
- NCT03296670
- Locations
- 🇨🇳
Ren Ji Hospital Afflited to School of Medicine, Shanghai Jiao Tong University, ShangHai, China
Efficacy of Intracoronary Infusion of Different Medicine in STEMI Patients Undergoing Primary PCI
- Conditions
- Interventions
- First Posted Date
- 2017-08-17
- Last Posted Date
- 2017-08-17
- Lead Sponsor
- RenJi Hospital
- Target Recruit Count
- 600
- Registration Number
- NCT03252665
- Locations
- 🇨🇳
Ren Ji Hospital Afflited to School of Medicine, Shanghai Jiao Tong University, ShangHai, China
Effects of Sublingual and Transdermal Administration of Nitroglycerin for Coronary CT Angiography on Image Quality
- First Posted Date
- 2016-11-11
- Last Posted Date
- 2019-09-17
- Lead Sponsor
- Massachusetts General Hospital
- Target Recruit Count
- 198
- Registration Number
- NCT02961946
- Locations
- 🇺🇸
Massachusetts General Hospital, Boston, Massachusetts, United States
The Role of Nitric Oxide in Cognition in Schizophrenia
- Conditions
- Interventions
- First Posted Date
- 2016-09-20
- Last Posted Date
- 2019-08-13
- Lead Sponsor
- King's College London
- Target Recruit Count
- 19
- Registration Number
- NCT02906553
- Locations
- 🇬🇧
South London and Maudsley, London, United Kingdom
Vericiguat Drug-drug Interaction With Nitroglycerin in Stable Coronary Artery Disease Patients
- Conditions
- Interventions
- First Posted Date
- 2015-12-01
- Last Posted Date
- 2021-12-29
- Lead Sponsor
- Bayer
- Target Recruit Count
- 36
- Registration Number
- NCT02617550
Topical Glyceryl Trinitrate (GTN) and Eccentric Exercises in the Treatment of Midportion Achilles Tendinopathy
- Conditions
- Interventions
- First Posted Date
- 2015-07-16
- Last Posted Date
- 2019-06-06
- Lead Sponsor
- Royal College of Surgeons, Ireland
- Target Recruit Count
- 76
- Registration Number
- NCT02499484
- Locations
- 🇮🇪
Connolly Hospital, Blanchardstown, Dublin, Ireland
Clinical Trial of Topically-applied Glyceryl Trinitrate (GTN) for the Treatment of Erectile Dysfunction (ED)
- Conditions
- Interventions
- First Posted Date
- 2015-07-13
- Last Posted Date
- 2020-02-12
- Lead Sponsor
- Futura Medical Developments Ltd.
- Target Recruit Count
- 232
- Registration Number
- NCT02495467
- Locations
- 🇬🇧
Richmond Pharmacology Ltd., Croydon, Surrey, United Kingdom
Role of Sympathetic Activity and Splanchnic Capacitance in Hypertension
- Conditions
- Interventions
- First Posted Date
- 2015-04-24
- Last Posted Date
- 2024-08-09
- Lead Sponsor
- Vanderbilt University
- Target Recruit Count
- 12
- Registration Number
- NCT02425566
- Locations
- 🇺🇸
Autonomic Dysfunction Center, Nashville, Tennessee, United States
Topical Nitroglycerin To Prevent Radial Artery Occlusion After Transradial Access: NTP-RAO Trial
- First Posted Date
- 2015-04-09
- Last Posted Date
- 2019-09-17
- Lead Sponsor
- Total Cardiovascular Solutions
- Target Recruit Count
- 2400
- Registration Number
- NCT02413268
- Locations
- 🇮🇳
Apex Heart Institute, Ahmedabad, Gujarat, India
Randomized Clinical Trial Comparing Transradial Catheterization With or Without Spasmolytic Drugs
- First Posted Date
- 2015-01-21
- Last Posted Date
- 2019-05-31
- Lead Sponsor
- Instituto de Cardiologia de Santa Catarina
- Target Recruit Count
- 328
- Registration Number
- NCT02343276
- Locations
- 🇧🇷
Instituto de Cardiologia de Santa Catarina, São Jose, SC, Brazil
Drug Development Updates
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