Midazolam
- Generic Name
- Midazolam
- Brand Names
- Buccolam, Busulfex, Nayzilam, Seizalam
- Drug Type
- Small Molecule
- Chemical Formula
- C18H13ClFN3
- CAS Number
- 59467-70-8
- Unique Ingredient Identifier
- R60L0SM5BC
- Background
Midazolam is a short-acting hypnotic-sedative drug with anxiolytic, muscle relaxant, anticonvulsant, sedative, hypnotic, and amnesic properties. It belongs to a class of drugs called benzodiazepines. This drug is unique from others in this class due to its rapid onset of effects and short duration of action. Midazolam is available by oral, rectal, intranasal...
- Indication
Midazolam has different indications depending on its formulation by the FDA.
Nasal
...
- Associated Conditions
- Epileptic seizure, Status Epilepticus
- Associated Therapies
- Anaesthesia, Anxiolytic therapy therapy, Sedation for mechanically-ventilated patients, Preoperative amnesia therapy, Preoperative sedation therapy
Propofol and Fentanyl Versus Midazolam and Fentanyl for Endoscopy Sedation in Cirrhotic Patients
- First Posted Date
- 2009-05-21
- Last Posted Date
- 2009-05-25
- Lead Sponsor
- Federal University of São Paulo
- Target Recruit Count
- 210
- Registration Number
- NCT00906139
- Locations
- 🇧🇷
Federal University of São Paulo, São Paulo, Brazil
Efficacy of Moderate Sedation for Dental Treatment of Young Children
- Conditions
- Interventions
- First Posted Date
- 2009-05-15
- Last Posted Date
- 2015-01-19
- Lead Sponsor
- Universidade Federal de Goias
- Target Recruit Count
- 41
- Registration Number
- NCT00902395
- Locations
- 🇧🇷
Dental School, Goiania, Goias, Brazil
Midazolam Effect in Children Undergoing Voiding Cystourethrogram (VCUG)
- First Posted Date
- 2009-05-07
- Last Posted Date
- 2016-12-09
- Lead Sponsor
- Washington University School of Medicine
- Target Recruit Count
- 44
- Registration Number
- NCT00894465
- Locations
- 🇺🇸
Washington University, ST Louis, Missouri, United States
Comparing the Effect of Dexmedetomidine With Midazolam on Sedation, Oxidative Stress, and Microcirculation in Intensive Care Unit
- Conditions
- Interventions
- First Posted Date
- 2009-04-22
- Last Posted Date
- 2012-11-16
- Lead Sponsor
- National Taiwan University Hospital
- Target Recruit Count
- 33
- Registration Number
- NCT00886275
- Locations
- 🇨🇳
National Taiwan University Hospital, Taipei, Taiwan
The Effect of High-dose Remifentanil on Established Capsaicin-induced Hyperalgesia in Human Volunteers
- First Posted Date
- 2009-04-22
- Last Posted Date
- 2009-11-18
- Lead Sponsor
- Medical University of Vienna
- Target Recruit Count
- 24
- Registration Number
- NCT00886106
- Locations
- 🇦🇹
Department of Anaesthesia, Medical University of Vienna, Vienna, Austria
Clown Doctors and a Sedative Premedicant for Children Undergoing Surgery
- First Posted Date
- 2009-04-22
- Last Posted Date
- 2009-10-20
- Lead Sponsor
- Shaare Zedek Medical Center
- Target Recruit Count
- 80
- Registration Number
- NCT00886314
- Locations
- 🇮🇱
Shaare Zedek Medical Center, Jerusalem, Israel
A Phase I Study to Investigate the Safety, Pharmacokinetics, and Pharmacodynamics of GSK2118436 in Subjects With Solid Tumors
- First Posted Date
- 2009-04-13
- Last Posted Date
- 2017-11-13
- Lead Sponsor
- GlaxoSmithKline
- Target Recruit Count
- 170
- Registration Number
- NCT00880321
- Locations
- 🇦🇺
GSK Investigational Site, Nedlands, Western Australia, Australia
Study Evaluating Safety and Efficacy of Dexmedetomidine (DEX) in Intubated and Mechanically Ventilated Pediatric Intensive Care Unit (PICU) Subjects
- Conditions
- Interventions
- First Posted Date
- 2009-04-03
- Last Posted Date
- 2015-08-14
- Lead Sponsor
- Hospira, now a wholly owned subsidiary of Pfizer
- Target Recruit Count
- 175
- Registration Number
- NCT00875550
- Locations
- 🇺🇸
Pediatric Critical Care, Los Angeles, California, United States
🇺🇸Advocate Lutheran General Children's Hospital, Park Ridge, Illinois, United States
🇺🇸University of Chicago Comer Children's Hospital, Chicago, Illinois, United States
Pilot Study Evaluating Stress Response and Immune Function in Mechanically Ventilated Patients With Alcohol Use Disorders Treated With Propofol or Midazolam
- Conditions
- Interventions
- First Posted Date
- 2009-03-30
- Last Posted Date
- 2016-03-01
- Lead Sponsor
- Virginia Commonwealth University
- Registration Number
- NCT00871039
- Locations
- 🇺🇸
Virginia Commonwealth University Medical Center (formerly known as Medical College of Virginia), Richmond, Virginia, United States
🇺🇸Virginia Commonwealth University Medical Center, Richmond, Virginia, United States
Dose-Finding Safety Study Evaluating Remimazolam (CNS 7056) in Patients Undergoing Diagnostic Upper GI Endoscopy
- First Posted Date
- 2009-03-26
- Last Posted Date
- 2019-01-08
- Lead Sponsor
- Paion UK Ltd.
- Target Recruit Count
- 100
- Registration Number
- NCT00869440
- Locations
- 🇺🇸
Wake Research Associates, Raleigh, North Carolina, United States
🇺🇸Advanced Clinical Research Institute, Anaheim, California, United States
🇺🇸Helen Keller Hospital, Sheffield, Alabama, United States
Drug Development Updates
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