Propofol

Generic Name: Propofol

Brand Names: Diprivan

Drug Type: Small Molecule

Chemical Formula: C_₁₂H_₁₈O

CAS Number: 2078-54-8

Unique Ingredient Identifier: YI7VU623SF

Background: Propofol is an intravenous anaesthetic agent used for induction and maintenance of general anaesthesia. IV administration of propfol is used to induce unconsciousness after which anaesthesia may be maintained using a combination of medications. Recovery from propofol-induced anaesthesia is generally rapid and associated with less frequent side effects (e.g. ...

Indication: Used for induction and/or maintenance of anaesthesia and for management of refractory status epilepticus.

Associated Conditions: -

Associated Therapies: Induction of anesthesia therapy, Maintenance of anesthesia therapy, Monitored anesthesia care sedation, Sedative therapy

Clinical Trials

Ketamine Sedation As Neuroprotective Agent Following Out-of-hospital Cardiac Arrest

Phase 2

Recruiting

Conditions: Out-of-hospital Cardiac Arrest (OHCA)

Interventions: Drug: esketamine hydrochloride
Drug: propofol

First Posted Date: 2024-12-20

Last Posted Date: 2024-12-20

Lead Sponsor: Christian Hassager

Target Recruit Count: 282

Registration Number: NCT06744361

Locations: 🇩🇰
Department of Cardiology, Rigshospitalet, Copenhagen, Denmark
🇩🇰
Odense University Hospital, Odense C, Denmark

Pro-Epileptic Effects of IV Ketamine

Phase 4

Active, not recruiting

Conditions: Epilepsy
Seizure

Interventions: Drug: Ketamine
Drug: Midazolam
Drug: Propofol

First Posted Date: 2024-12-19

Last Posted Date: 2024-12-20

Lead Sponsor: Haseki Training and Research Hospital

Target Recruit Count: 300

Registration Number: NCT06741930

Locations: 🇹🇷
Haseki Training and Research Hospital, Istanbul, Turkey

Ciprofol Based on Total Intravenous Anesthesia During Pediatric Laparoscopic Surgery

Not Applicable

Not yet recruiting

Conditions: Pediatric Hernia
Laparoscopic Surgery
Appendicitis, Surgery

Interventions: Drug: Ciprofol
Drug: Propofol

First Posted Date: 2024-12-16

Last Posted Date: 2024-12-16

Lead Sponsor: Tongji Hospital

Target Recruit Count: 86

Registration Number: NCT06735430

Clinical Study of Fospropofol Disodium for Injection in the Painless Endoscopic Diagnosis and Treatment

Not Applicable

Not yet recruiting

Conditions: Efficacy and Safety

Interventions: Drug: fospropofol Disodium for injection
Drug: Propofol

First Posted Date: 2024-12-13

Last Posted Date: 2024-12-13

Lead Sponsor: Affiliated Hospital of Nantong University

Target Recruit Count: 426

Registration Number: NCT06732427

Locations: 🇨🇳
Yongtao Gao, Nantong, Jiangsu, China

The Efficacy and Safety of Remimazolam Besylate for Cardiac Anesthesia

Early Phase 1

Not yet recruiting

Conditions: Anesthesia

Interventions: Drug: remimazolam besylate
Drug: propofol

First Posted Date: 2024-12-05

Last Posted Date: 2024-12-05

Lead Sponsor: Chinese Academy of Medical Sciences, Fuwai Hospital

Target Recruit Count: 320

Registration Number: NCT06717945

Effect of Propofol Administration Time on the Incidence and Severity of Intrathecal Morphine-induced Pruritus in Parturient Undergoing Elective Cesarean Delivaries

Phase 4

Not yet recruiting

Conditions: Cesarean Section

Interventions: Drug: Morphine intrathecal
Drug: propofol

First Posted Date: 2024-12-04

Last Posted Date: 2024-12-04

Lead Sponsor: Assiut University

Target Recruit Count: 204

Registration Number: NCT06715657

Remimazolam Besylate in Sedation of Postcardioperative Patients

Not Applicable

Not yet recruiting

Conditions: Remimazolam
Propofol
Sedation
Mechanical Ventilation
Intensive Care
Cardiac Surgery

Interventions: Drug: Remimazolam
Drug: Propofol

First Posted Date: 2024-12-04

Last Posted Date: 2024-12-04

Lead Sponsor: First Affiliated Hospital of Zhejiang University

Target Recruit Count: 120

Registration Number: NCT06716840

Comparison of General Anesthesia Hemodynamics Between R and P in Patients Undergoing Laparoscopic Hepatectomy

Phase 3

Completed

Conditions: Hypotension During Surgery

Interventions: Drug: Remimazolam
Drug: propofol

First Posted Date: 2024-12-03

Last Posted Date: 2024-12-03

Lead Sponsor: Sun Yat-sen University

Target Recruit Count: 88

Registration Number: NCT06714669

Locations: 🇨🇳
Sun Yat-san University Cancer Center, Guangzhou, Guangdong, China

The Potential Protective Effect of Using Muscle Relaxants During Electroporation Ablation (PFA)

Not Applicable

Recruiting

Conditions: Kidney Failure, Acute
Myopathy; Drugs
Heart Arrhythmia
Succinylcholine Sensitivity
Muscle Relaxation
General Anesthetic Drug Adverse Reaction
Projection

Interventions: Drug: Propofol
Drug: Rocuronium

First Posted Date: 2024-11-27

Last Posted Date: 2024-11-27

Lead Sponsor: 4th Military Clinical Hospital with Polyclinic, Poland

Target Recruit Count: 32

Registration Number: NCT06707532

Locations: 🇵🇱
4th Military Clinical Hospital with Polyclinic, Wrocław, Dolnośląskie, Poland

RCT Comparing Remimazolam With Propofol Under EEG DSA Guidance During Cardiac Electrophysiology Studies and Ablation

Not Applicable

Conditions: Hemodynamic
Remimazolam
Propofol
Cardiac Electrophysiology

Interventions: Drug: Propofol
Drug: Remimazolam
Device: With intubation and controlled ventilation to maintain airway
Device: Maintain spontaneous ventilation without intubation

First Posted Date: 2024-11-22

Last Posted Date: 2024-11-22

Lead Sponsor: Taipei Veterans General Hospital, Taiwan

Target Recruit Count: 200

Registration Number: NCT06700681

Locations: 🇨🇳
Taipei Veterans General Hospital, Taipei, Taiwan

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