Propofol

Generic Name: Propofol

Brand Names: Diprivan

Drug Type: Small Molecule

Chemical Formula: C_₁₂H_₁₈O

CAS Number: 2078-54-8

Unique Ingredient Identifier: YI7VU623SF

Background: Propofol is an intravenous anaesthetic agent used for induction and maintenance of general anaesthesia. IV administration of propfol is used to induce unconsciousness after which anaesthesia may be maintained using a combination of medications. Recovery from propofol-induced anaesthesia is generally rapid and associated with less frequent side effects (e.g. ...

Indication: Used for induction and/or maintenance of anaesthesia and for management of refractory status epilepticus.

Associated Conditions: -

Associated Therapies: Induction of anesthesia therapy, Maintenance of anesthesia therapy, Monitored anesthesia care sedation, Sedative therapy

Clinical Trials

The Effect of Sevoflurane on Airway Hyperreactivity During the Perioperative Period.

Completed

Conditions: RSV Infection in Children Less Than 5 Years of Age
General Anesthesia

Interventions: Drug: Sevoflurane (Volatile Anesthetic)
Drug: propofol

First Posted Date: 2024-11-19

Last Posted Date: 2024-11-19

Lead Sponsor: First Hospital of China Medical University

Target Recruit Count: 80

Registration Number: NCT06694675

Locations: 🇨🇳
First hospital of China Mdical University, Shenyang, Liaoning, China
🇨🇳
First Hospital of China Medical University, Shenyang, Liaoning, China

Clinical Studies of the Efficacy and Safety of Remimazolam for Anesthesia Induction and Maintenance in Elderly Patients

Phase 4

Not yet recruiting

Conditions: Efficacy and Safety

Interventions: Drug: Remimazolam
Drug: Propofol

First Posted Date: 2024-11-15

Last Posted Date: 2024-12-16

Lead Sponsor: Affiliated Hospital of Nantong University

Target Recruit Count: 60

Registration Number: NCT06690424

Effects of Ciprofol on Postoperative Delirium and Outcomes in Elderly Patients Undergoing Major Thoracic Surgery

Phase 4

Not yet recruiting

Conditions: Postoperative Delirium (POD)

Interventions: Drug: Ciprofol
Drug: Propofol

First Posted Date: 2024-11-05

Last Posted Date: 2024-11-05

Lead Sponsor: Wang Tianlong

Target Recruit Count: 214

Registration Number: NCT06674226

Locations: 🇨🇳
Xuanwu Hospital, Beijing, Beijing, China

Comparison of High Flow Vs Standard Nasal Cannula in Children with Burns Under Sedoanalgesia

Not Applicable

Completed

Conditions: Burns

Interventions: Other: Conventional Nasal Cannula
Other: High-flow nasal cannula
Drug: midazolam, ketamine, propofol
Drug: Propofol

First Posted Date: 2024-10-29

Last Posted Date: 2024-11-19

Lead Sponsor: Zeliha Tuncel

Target Recruit Count: 50

Registration Number: NCT06663293

Locations: 🇹🇷
Umraniye Education and Research hospital, Istanbul, Turkey

Effect of Propofol and Sevoflurane Anesthesia on HSP70 Expression in Tumor Cells

Early Phase 1

Active, not recruiting

Conditions: Anesthesia
Cancer Recurrence
Cancer

Interventions: Drug: Propofol
Drug: Sevoflurane

First Posted Date: 2024-10-04

Last Posted Date: 2024-11-28

Lead Sponsor: Saint Petersburg State University, Russia

Target Recruit Count: 10

Registration Number: NCT06626711

Locations: 🇷🇺
Saint Petersburg State University Hospital, Saint Petersburg, Russian Federation

The Impact of Preoperative Suggestion on Dreaming

Not Applicable

Conditions: Dream, Day
Ketamine Adverse Reaction
Propofol Adverse Reaction

Interventions: Other: Control Group
Other: Suggestion Group

First Posted Date: 2024-09-24

Last Posted Date: 2024-09-24

Lead Sponsor: Wonkwang University Hospital

Target Recruit Count: 250

Registration Number: NCT06609538

Locations: 🇰🇷
WonwangUH, Iksan, Please Select, Korea, Republic of

Efficacy and Safety of Fospropofol in Adult Laparoscopic Surgery: A Clinical Trial

Phase 4

Not yet recruiting

Conditions: Drug Safety

Interventions: Drug: Propofol
Drug: Fospropofol

First Posted Date: 2024-08-27

Last Posted Date: 2024-08-27

Lead Sponsor: Hui Xu

Target Recruit Count: 373

Registration Number: NCT06573489

The Effect of Dexmedetomidine on the Renal Functions in Septic Critically Ill Patients

Phase 4

Recruiting

Conditions: Sepsis
Septic Shock
Acute Kidney Injury

Interventions: Drug: Dexmedetomidine
Drug: Propofol

First Posted Date: 2024-08-26

Last Posted Date: 2024-10-09

Lead Sponsor: Cairo University

Target Recruit Count: 128

Registration Number: NCT06570187

Locations: 🇪🇬
Cairo University, Cairo, Egypt

Effect of Remazolam on Hemodynamics During Hepatectomy

Phase 4

Not yet recruiting

Conditions: Hemodynamic Instability

Interventions: Drug: Remimazolam
Drug: Propofol

First Posted Date: 2024-08-22

Last Posted Date: 2024-08-23

Lead Sponsor: Jun Zhang

Target Recruit Count: 70

Registration Number: NCT06565715

Locations: 🇨🇳
Fudan University Shanghai Cancer Center, Shanghai, China

Laparoscopic Transversus Abdominis Plane Block Versus Erector Spinae Plane Block in Bariatric Surgery

Not Applicable

Recruiting

Conditions: Analgesia
Pain, Postoperative
Obesity

Interventions: Procedure: Erector spinae block
Procedure: Transversus abdominis block
Procedure: Bariatric surgery
Device: Endotracheal intubation
Drug: Propofol

First Posted Date: 2024-08-21

Last Posted Date: 2024-08-23

Lead Sponsor: Cairo University

Target Recruit Count: 90

Registration Number: NCT06564610

Locations: 🇪🇬
Faculty of medicine, Cairo University., Cairo, Egypt

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