Propofol
- Generic Name
- Propofol
- Brand Names
- Diprivan
- Drug Type
- Small Molecule
- Chemical Formula
- C12H18O
- CAS Number
- 2078-54-8
- Unique Ingredient Identifier
- YI7VU623SF
- Background
Propofol is an intravenous anaesthetic agent used for induction and maintenance of general anaesthesia. IV administration of propfol is used to induce unconsciousness after which anaesthesia may be maintained using a combination of medications. Recovery from propofol-induced anaesthesia is generally rapid and associated with less frequent side effects (e.g. drowsiness, nausea, vomiting) than with thiopental, methohexital, and etomidate. Propofol may be used prior to diagnostic procedures requiring anaesthesia, in the management of refractory status epilepticus, and for induction and/or maintenance of anaesthesia prior to and during surgeries.
- Indication
Used for induction and/or maintenance of anaesthesia and for management of refractory status epilepticus.
- Associated Conditions
- -
- Associated Therapies
- Induction of anesthesia therapy, Maintenance of anesthesia therapy, Monitored anesthesia care sedation, Sedative therapy
Propofol Versus Esketamine for Rapid Sequence Intubation in Critically Ill Patients
- Conditions
- Interventions
- First Posted Date
- 2021-10-25
- Last Posted Date
- 2023-07-14
- Lead Sponsor
- Federal University of São Paulo
- Target Recruit Count
- 170
- Registration Number
- NCT05092152
- Locations
- 🇧🇷
Federal University of São Paulo, São Paulo, Brazil
Desflurane and Anesthesia Recovery Period in Endonasal Endoscopic Pituitary Adenoma Resection
- First Posted Date
- 2021-10-21
- Last Posted Date
- 2023-06-22
- Lead Sponsor
- Beijing Tiantan Hospital
- Target Recruit Count
- 112
- Registration Number
- NCT05088252
- Locations
- 🇨🇳
Ruquan Han, Beijing, Beijing, China
Effect of Propofol on Postoperative Nausea and Vomiting.
- Conditions
- Interventions
- First Posted Date
- 2021-10-08
- Last Posted Date
- 2023-01-31
- Lead Sponsor
- Pakistan Air Force (PAF) Hospital Islamabad
- Target Recruit Count
- 60
- Registration Number
- NCT05071794
- Locations
- 🇵🇰
PAF Hospital Islamabad, Islamabad, Federal, Pakistan
Efficacy and Safety of Ciprofol Compared to Propofol for Nonintubated General Anesthesia in Patients Undergoing TAVR
- First Posted Date
- 2021-09-05
- Last Posted Date
- 2021-09-05
- Lead Sponsor
- Haisco Pharmaceutical Group Co., Ltd.
- Target Recruit Count
- 24
- Registration Number
- NCT05035069
- Locations
- 🇨🇳
Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, Zhejiang, China
Pilot Study of Ketamine Sedation for Aneurysmal Subarachnoid Hemorrhage
- Conditions
- Interventions
- First Posted Date
- 2021-09-02
- Last Posted Date
- 2023-05-01
- Lead Sponsor
- Jenna L Leclerc MD, PhD
- Registration Number
- NCT05032118
A Study of Danavorexton in Anesthetized Adults
- Conditions
- Interventions
- First Posted Date
- 2021-08-27
- Last Posted Date
- 2022-05-10
- Lead Sponsor
- Takeda
- Target Recruit Count
- 28
- Registration Number
- NCT05025397
- Locations
- 🇺🇸
Endeavor Clinical Trials, San Antonio, Texas, United States
Compare Hemodynamic Parameters of Propofol and Sevoflurane During CPB Time in Undergoing CABG to Avoid Lactate Level
- First Posted Date
- 2021-08-13
- Last Posted Date
- 2021-08-13
- Lead Sponsor
- Chaudhry Pervaiz Elahi Institute of Cardiology
- Target Recruit Count
- 126
- Registration Number
- NCT05004545
- Locations
- 🇵🇰
Cardiac Surgery ICU, Multan, Punjab, Pakistan
Ketofol Versus Propofol in Urgent ERCP for Acute Cholangitis
- Conditions
- Interventions
- First Posted Date
- 2021-08-10
- Last Posted Date
- 2021-08-10
- Lead Sponsor
- Assiut University
- Target Recruit Count
- 100
- Registration Number
- NCT04997967
- Locations
- 🇪🇬
Assiut University, Assiut, Egypt
Phase III Clinical Trial Evaluating the Efficacy and Safety of Ciprofol Injection for the Induction of Sedation/Anesthesia in Subjects Undergoing Gynecological Outpatient Surgeries
- First Posted Date
- 2021-07-12
- Last Posted Date
- 2022-06-02
- Lead Sponsor
- Haisco Pharmaceutical Group Co., Ltd.
- Target Recruit Count
- 135
- Registration Number
- NCT04958746
- Locations
- 🇨🇳
Peking University First Hospital, Beijing, China
Remimazolam and Endovascular Procedures of Cerebrovascular Diseases
- Conditions
- Interventions
- First Posted Date
- 2021-07-06
- Last Posted Date
- 2022-10-20
- Lead Sponsor
- Air Force Military Medical University, China
- Target Recruit Count
- 142
- Registration Number
- NCT04950621
- Locations
- 🇨🇳
Xijing hospital, Xi'an, Shaanxi, China
Drug Development Updates
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