Flurbiprofen

Generic Name
Flurbiprofen
Brand Names
-
Drug Type
Small Molecule
Chemical Formula
C15H13FO2
CAS Number
5104-49-4
Unique Ingredient Identifier
5GRO578KLP
Background

Flurbiprofen, a propionic acid derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with antipyretic and analgesic activity. Oral formulations of flurbiprofen may be used for the symptomatic treatment of rheumatoid arthritis, osteoarthritis and anklylosing spondylitis. Flurbiprofen may also be used topically prior to ocular surgery to prevent or red...

Indication

Flurbiprofen tablets are indicated for the acute or long-term symptomatic treatment of rheumatoid arthritis, osteorarthritis and anklosing spondylitis. It may also be used to treat pain associated with dysmenorrhea and mild to moderate pain accompanied by inflammation (e.g. bursitis, tendonitis, soft tissue trauma). Topical ophthalmic formulations may be use...

Associated Conditions
Ankylosing Spondylitis (AS), Back Pain, Acute, Chronic Back Pain, Menstrual Distress (Dysmenorrhea), Muscle Spasms, Non-Articular Rheumatic Muscle Spasms, Osteoarthritis (OA), Pain, Pain, Inflammatory, Post Traumatic Pain, Postoperative pain, Rheumatoid Arthritis, Spinal pain
Associated Therapies
-

CYP2C9 Activity Evaluated With a Simple Finger Prick

First Posted Date
2009-12-04
Last Posted Date
2011-01-11
Lead Sponsor
University Hospital, Geneva
Target Recruit Count
10
Registration Number
NCT01026714
Locations
🇨🇭

University Hospitals, Geneva 14, Switzerland

Validation Study of Multiple Probe Compounds for Drug Interaction Evaluation

First Posted Date
2009-08-24
Last Posted Date
2018-01-04
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
87
Registration Number
NCT00964106
Locations
🇰🇷

GSK Investigational Site, Seoul, Korea, Republic of

Drug Interaction Study of Darunavir/Ritonavir and Lopinavir/Ritonavir on GSK2248761 PK and CYP450 Probe Drugs

First Posted Date
2009-06-15
Last Posted Date
2010-11-03
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
24
Registration Number
NCT00920088
Locations
🇺🇸

GSK Investigational Site, Baltimore, Maryland, United States

Effect of GSK376501 on CYP450 Activity in Healthy Adult Subjects

First Posted Date
2008-02-14
Last Posted Date
2017-09-11
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
23
Registration Number
NCT00615212
Locations
🇺🇸

GSK Investigational Site, Buffalo, New York, United States

Local Flurbiprofen to Treat Pain Following Wisdom Tooth Extraction

Phase 2
Completed
Conditions
First Posted Date
1999-11-04
Last Posted Date
2008-03-04
Lead Sponsor
National Institute of Dental and Craniofacial Research (NIDCR)
Target Recruit Count
100
Registration Number
NCT00001724
Locations
🇺🇸

National Institute of Dental And Craniofacial Research (NIDCR), Bethesda, Maryland, United States

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