Morphine
- Generic Name
- Morphine
- Brand Names
- Arymo, Avinza, Doloral, Duramorph, Embeda, Infumorph, Kadian, M-ediat, M-eslon, MSIR, Mitigo, Ms Contin, Statex
- Drug Type
- Small Molecule
- Chemical Formula
- C17H19NO3
- CAS Number
- 57-27-2
- Unique Ingredient Identifier
- 76I7G6D29C
- Background
Morphine, the main alkaloid of opium, was first obtained from poppy seeds in 1805. It is a potent analgesic, though its use is limited due to tolerance, withdrawal, and the risk of abuse. Morphine is still routinely used today, though there are a number of semi-synthetic opioids of varying strength such as codeine, fentanyl, methadone, hydrocodone, hydromorphone, meperidine, and oxycodone.
Morphine was granted FDA approval in 1941.
- Indication
Morphine is used for the management of chronic, moderate to severe pain.
Opiods, including morphine, are effective for the short term management of pain. Patients taking opioids long term may need to be monitored for the development of physical dependence, addiction disorder, and drug abuse.
- Associated Conditions
- Chronic Pain, Severe Pain
- Associated Therapies
- -
Pain Treatment for Sciatica
- Conditions
- RadiculopathySciatica
- First Posted Date
- 2001-02-05
- Last Posted Date
- 2017-07-02
- Lead Sponsor
- National Institute of Dental and Craniofacial Research (NIDCR)
- Target Recruit Count
- 80
- Registration Number
- NCT00009672
- Locations
- 🇺🇸
National Institutes of Health Clinical Center, 9000 Rockville Pike, Bethesda, Maryland, United States
Study of Morphine in Postoperative Infants to Allow Normal Ventilation
- Conditions
- Infant, Newborn, DiseasesPain
- First Posted Date
- 2000-02-25
- Last Posted Date
- 2015-03-25
- Lead Sponsor
- Seattle Children's Hospital
- Target Recruit Count
- 100
- Registration Number
- NCT00004696
Phase III Randomized Controlled Study of Morphine and Nortriptyline in the Management of Postherpetic Neuralgia
- Conditions
- PainHerpes Zoster
- First Posted Date
- 1999-10-19
- Last Posted Date
- 2005-06-24
- Lead Sponsor
- National Center for Research Resources (NCRR)
- Target Recruit Count
- 120
- Registration Number
- NCT00004390
Activity Monitoring Assessment of Opiate Withdrawal - 4
- Conditions
- Opioid-Related Disorders
- First Posted Date
- 1999-09-21
- Last Posted Date
- 2017-01-31
- Lead Sponsor
- National Institute on Drug Abuse (NIDA)
- Registration Number
- NCT00000335
- Locations
- 🇺🇸
Washington DC VA, Washington, District of Columbia, United States
Drug Development Updates
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