Morphine
- Generic Name
- Morphine
- Brand Names
- Arymo, Avinza, Doloral, Duramorph, Embeda, Infumorph, Kadian, M-ediat, M-eslon, MSIR, Mitigo, Ms Contin, Statex
- Drug Type
- Small Molecule
- Chemical Formula
- C17H19NO3
- CAS Number
- 57-27-2
- Unique Ingredient Identifier
- 76I7G6D29C
- Background
Morphine, the main alkaloid of opium, was first obtained from poppy seeds in 1805. It is a potent analgesic, though its use is limited due to tolerance, withdrawal, and the risk of abuse. Morphine is still routinely used today, though there are a number of semi-synthetic opioids of varying strength such as codeine, fentanyl, methadone, hydrocodone, hydromorp...
- Indication
Morphine is used for the management of chronic, moderate to severe pain.
Opiods, including morphine, are effective for the short term management of pain. Patients taking opioids long term may need to be monitored for the development of physical dependence, addiction disorder, and drug abuse.
- Associated Conditions
- Chronic Pain, Severe Pain
- Associated Therapies
- -
A Study to Evaluate the Efficacy and Safety of Tapentadol (CG5503) in the Treatment of Acute Pain After Abdominal Hysterectomy
- Conditions
- Interventions
- First Posted Date
- 2007-05-24
- Last Posted Date
- 2019-10-28
- Lead Sponsor
- Grünenthal GmbH
- Target Recruit Count
- 854
- Registration Number
- NCT00478023
- Locations
- 🇷🇺
Site 44, Moscow, Russian Federation
🇸🇰Site 52, Bratislava, Slovakia
🇸🇰Site 62, Kosice, Slovakia
Morphine Analgesia in Patients With Acute Appendicitis
- Conditions
- First Posted Date
- 2007-05-22
- Last Posted Date
- 2007-05-22
- Lead Sponsor
- Tehran University of Medical Sciences
- Target Recruit Count
- 71
- Registration Number
- NCT00477061
- Locations
- 🇮🇷
Sina General Hospital, Tehran, Iran, Islamic Republic of
Buprenorphine's Dose Response Curve
- Conditions
- Interventions
- First Posted Date
- 2007-04-13
- Last Posted Date
- 2017-03-03
- Lead Sponsor
- Johns Hopkins University
- Target Recruit Count
- 12
- Registration Number
- NCT00460239
- Locations
- 🇺🇸
Johns Hopkins University (BPRU) Bayview Campus, Baltimore, Maryland, United States
A Efficacy and Safety Trial of Controlled Release (CR) Morphine in Cancer Patients
- First Posted Date
- 2007-03-12
- Last Posted Date
- 2016-08-29
- Lead Sponsor
- Egalet Ltd
- Target Recruit Count
- 36
- Registration Number
- NCT00446069
- Locations
- 🇱🇹
Site 51, Kaunas, Lithuania
🇵🇱Site 62, Poznań, Poland
🇵🇱Site 64, Wrocław, Poland
Oxycodone or Standard Pain Therapy in Treating Patients With Cancer Pain
- Conditions
- First Posted Date
- 2006-09-21
- Last Posted Date
- 2013-08-02
- Target Recruit Count
- 30
- Registration Number
- NCT00378937
A Study of the Safety and Efficacy of Combination Therapy With Morphine, Phenylephrine and Sorbitol in Human Subjects
- Conditions
- Interventions
- First Posted Date
- 2006-09-12
- Last Posted Date
- 2008-04-15
- Lead Sponsor
- BioLineRx, Ltd.
- Target Recruit Count
- 9
- Registration Number
- NCT00374881
- Locations
- 🇮🇱
Hadassah En Kerem Medical Centre, Jerusalem, Israel
🇮🇱Hadassah Hebrew University Medical Center, Department of Anesthesiology, Jerusalem, Israel
Topical Morphine for Analgesia in Patients With Skin Grafts
- Conditions
- Interventions
- First Posted Date
- 2006-08-09
- Last Posted Date
- 2022-05-03
- Lead Sponsor
- Rambam Health Care Campus
- Registration Number
- NCT00362219
- Locations
- 🇮🇱
Department of Plastic Surgery, Rambam Medical Center, Haifa, Israel
Analgetic and Anxiolytic Effect of Preoperative Pregabalin
- Conditions
- Interventions
- First Posted Date
- 2006-07-19
- Last Posted Date
- 2011-07-20
- Lead Sponsor
- Asker & Baerum Hospital
- Target Recruit Count
- 50
- Registration Number
- NCT00353704
- Locations
- 🇳🇴
Asker and Baerum Hospital, Rud, Norway
Intrathecal Ketorolac in Patients With Intrathecal Morphine Dose Escalation
- Conditions
- First Posted Date
- 2006-07-07
- Last Posted Date
- 2017-11-06
- Lead Sponsor
- Wake Forest University Health Sciences
- Registration Number
- NCT00349401
Trial Comparing Morphine to Hydromorphone in Elderly Patients With Severe Pain
- First Posted Date
- 2006-03-21
- Last Posted Date
- 2018-08-20
- Lead Sponsor
- Montefiore Medical Center
- Target Recruit Count
- 194
- Registration Number
- NCT00305058
- Locations
- 🇺🇸
Montefiore Medical Center, Bronx, New York, United States
Drug Development Updates
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