Ibuprofen
- Generic Name
- Ibuprofen
- Brand Names
- Addaprin, Advil, Advil Cold and Sinus, Advil Congestion Relief, Advil PM, Advil Sinus Congestion and Pain, Alivio, Caldolor, Cedaprin, Children's Ibuprofen, Diphen, Duexis, Ibu, Ibutab, Junior Strength Motrin, Motrin, Motrin PM, Neoprofen, Nuprin, Pedea, Proprinal, Reprexain, Sudafed PE Head Congestion Plus Pain, Vicoprofen, Wal-profen Congestion Relief and Pain, Ibuprofen Gen.Orph
- Drug Type
- Small Molecule
- Chemical Formula
- C13H18O2
- CAS Number
- 15687-27-1
- Unique Ingredient Identifier
- WK2XYI10QM
- Background
Ibuprofen is a non-steroidal anti-inflammatory drug (NSAID) derived from propionic acid and it is considered the first of the propionics. The formula of ibuprofen is 2-(4-isobutylphenyl) propionic acid and its initial development was in 1960 while researching for a safer alternative for aspirin. Ibuprofen was finally patented in 1961 and this drug was first ...
- Indication
Ibuprofen is the most commonly used and prescribed NSAID. It is a very common over-the-counter medication widely used as an analgesic, anti-inflammatory and antipyretic.
...
- Associated Conditions
- Acute Pain, Ankylosing Spondylitis (AS), Common Cold, Cystic Fibrosis (CF), Fever, Gastric Ulcer, Gout, Headache, Insomnia, Juvenile Idiopathic Arthritis (JIA), Menstrual Distress (Dysmenorrhea), Migraine, Mild pain, Nasal Congestion, Osteoarthritis (OA), Pain, Pain, Inflammatory, Patent Ductus Arteriosus (PDA), Pericarditis, Primary Dysmenorrhoea, Rheumatoid Arthritis, Severe Pain, Sinus pressure, Mild to moderate pain, Minor aches and pains, Moderate Pain
- Associated Therapies
- -
Comparison of Ibuprofen, Cyclobenzaprine, or Both for Acute Cervical Strain: A Randomized Clinical Trial
- Conditions
- Interventions
- First Posted Date
- 2008-11-13
- Last Posted Date
- 2012-11-21
- Lead Sponsor
- Stony Brook University
- Target Recruit Count
- 61
- Registration Number
- NCT00790270
- Locations
- 🇺🇸
Stony Brook University, Stony Brook, New York, United States
Study of the Effect of Dipyrone, Ibuprofen, Paracetamol and Parecoxib on the Platelet Aggregation in Analgetic Dosages
- Conditions
- Interventions
- First Posted Date
- 2008-10-01
- Last Posted Date
- 2008-10-01
- Lead Sponsor
- Ruhr University of Bochum
- Target Recruit Count
- 80
- Registration Number
- NCT00763997
- Locations
- 🇩🇪
BG University Hospital Bergmannsheil GmbH, Bochum, Germany
A Study to Test the Safety and Effectiveness of MK-0974 (Telcagepant) Co-administered With Ibuprofen or Acetaminophen in Patients With Migraines With or Without Aura (MK-0974-046)
- Conditions
- Interventions
- First Posted Date
- 2008-09-25
- Last Posted Date
- 2018-10-22
- Lead Sponsor
- Merck Sharp & Dohme LLC
- Target Recruit Count
- 683
- Registration Number
- NCT00758836
Ibuprofen or Morphine in Treating Pain in Patients Undergoing Pleurodesis for Malignant Pleural Effusion
- Conditions
- First Posted Date
- 2008-03-26
- Last Posted Date
- 2009-07-08
- Lead Sponsor
- Oxford University Hospitals NHS Trust
- Target Recruit Count
- 320
- Registration Number
- NCT00644319
- Locations
- 🇬🇧
Oxford Radcliffe Hospital, Oxford, England, United Kingdom
Efficacy and Safety of Celecoxib Versus Ibuprofen in the Treatment of Osteoarthritis of the Knee (Europe)
- Conditions
- Interventions
- First Posted Date
- 2008-03-07
- Last Posted Date
- 2021-02-21
- Target Recruit Count
- 388
- Registration Number
- NCT00630929
- Locations
- 🇬🇧
Pfizer Investigational Site, Wigan, United Kingdom
Interaction Between Antihypertensives and Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)
- Conditions
- Interventions
- First Posted Date
- 2008-03-07
- Last Posted Date
- 2008-03-10
- Lead Sponsor
- University Hospital of Split
- Target Recruit Count
- 88
- Registration Number
- NCT00631514
- Locations
- 🇭🇷
Split University School of Medicine. Family Practice Department, Split, Croatia
Multimodal Treatment Strategy for Cancer Cachexia
- Conditions
- Interventions
- First Posted Date
- 2008-02-28
- Last Posted Date
- 2016-02-12
- Lead Sponsor
- M.D. Anderson Cancer Center
- Target Recruit Count
- 15
- Registration Number
- NCT00625742
- Locations
- 🇺🇸
UT MD Anderson Cancer Center, Houston, Texas, United States
Ascorbic Acid and Ibuprofen in Infants With Hypoxic Ischemic Encephalopathy
- Conditions
- Interventions
- First Posted Date
- 2008-02-28
- Last Posted Date
- 2008-02-28
- Lead Sponsor
- Al-Azhar University
- Target Recruit Count
- 60
- Registration Number
- NCT00624871
- Locations
- 🇪🇬
Bab El-Shariya Hospital, Cairo, Egypt
Efficacy and Safety of Celecoxib Versus Ibuprofen in the Treatment of Osteoarthritis of the Knee (United States)
- Conditions
- Interventions
- First Posted Date
- 2008-02-22
- Last Posted Date
- 2021-02-21
- Target Recruit Count
- 393
- Registration Number
- NCT00620867
- Locations
- 🇺🇸
Pfizer Investigational Site, Danville, Virginia, United States
Double-Blind Follow-on Safety Study of HZT-501 (Ibuprofen 800 mg/Famotidine 26.6 mg) in Subjects Who Have Completed Participation in HZ-CA-301 (NCT00450658) or HZ-CA-303 (NCT00450216)
- Conditions
- Interventions
- First Posted Date
- 2008-02-12
- Last Posted Date
- 2024-12-17
- Lead Sponsor
- Amgen
- Target Recruit Count
- 179
- Registration Number
- NCT00613106
- Locations
- 🇺🇸
PRA International, San Diego, California, United States
Drug Development Updates
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