Ibuprofen
- Generic Name
- Ibuprofen
- Brand Names
- Addaprin, Advil, Advil Cold and Sinus, Advil Congestion Relief, Advil PM, Advil Sinus Congestion and Pain, Alivio, Caldolor, Cedaprin, Children's Ibuprofen, Diphen, Duexis, Ibu, Ibutab, Junior Strength Motrin, Motrin, Motrin PM, Neoprofen, Nuprin, Pedea, Proprinal, Reprexain, Sudafed PE Head Congestion Plus Pain, Vicoprofen, Wal-profen Congestion Relief and Pain, Ibuprofen Gen.Orph
- Drug Type
- Small Molecule
- Chemical Formula
- C13H18O2
- CAS Number
- 15687-27-1
- Unique Ingredient Identifier
- WK2XYI10QM
- Background
Ibuprofen is a non-steroidal anti-inflammatory drug (NSAID) derived from propionic acid and it is considered the first of the propionics. The formula of ibuprofen is 2-(4-isobutylphenyl) propionic acid and its initial development was in 1960 while researching for a safer alternative for aspirin. Ibuprofen was finally patented in 1961 and this drug was first ...
- Indication
Ibuprofen is the most commonly used and prescribed NSAID. It is a very common over-the-counter medication widely used as an analgesic, anti-inflammatory and antipyretic.
...
- Associated Conditions
- Acute Pain, Ankylosing Spondylitis (AS), Common Cold, Cystic Fibrosis (CF), Fever, Gastric Ulcer, Gout, Headache, Insomnia, Juvenile Idiopathic Arthritis (JIA), Menstrual Distress (Dysmenorrhea), Migraine, Mild pain, Nasal Congestion, Osteoarthritis (OA), Pain, Pain, Inflammatory, Patent Ductus Arteriosus (PDA), Pericarditis, Primary Dysmenorrhoea, Rheumatoid Arthritis, Severe Pain, Sinus pressure, Mild to moderate pain, Minor aches and pains, Moderate Pain
- Associated Therapies
- -
Efficacy and Safety Study of Caldolor (Intravenous Ibuprofen) in Hospitalized Adult and Pediatric Burn Patients
- First Posted Date
- 2008-02-04
- Last Posted Date
- 2011-08-11
- Lead Sponsor
- Cumberland Pharmaceuticals
- Target Recruit Count
- 61
- Registration Number
- NCT00606489
- Locations
- 🇺🇸
Orlando Regional Medical Center, Orlando, Florida, United States
🇮🇳Surya Hospitals Pvt. Ltd, Pune, India
🇮🇳Naik's Hospital, Baroda, Kothi, India
Comparison of the Efficacy of Topical Ibuprofen to Oral Ibuprofen in Adolescent Athletes
- First Posted Date
- 2007-12-05
- Last Posted Date
- 2015-01-14
- Lead Sponsor
- Akron Children's Hospital
- Target Recruit Count
- 60
- Registration Number
- NCT00567528
- Locations
- 🇺🇸
Sports Medicine Department at Akron Children's Hospital, Akron, Ohio, United States
Celecoxib, Ibuprofen and the Antiplatelet Effect of Aspirin
- Conditions
- Interventions
- First Posted Date
- 2007-11-30
- Last Posted Date
- 2007-11-30
- Lead Sponsor
- University of Chieti
- Target Recruit Count
- 24
- Registration Number
- NCT00565500
- Locations
- 🇮🇹
Ce.S.I., Center of Excellence on Aging, G. d'Annunzio University, Chieti, CH, Italy
Tolerability and Efficacy of Ibuprofen 800 mg in a Walking Model of Osteoarthritis Pain (0000-057)
- First Posted Date
- 2007-11-29
- Last Posted Date
- 2015-04-10
- Lead Sponsor
- Merck Sharp & Dohme LLC
- Target Recruit Count
- 33
- Registration Number
- NCT00565084
Pilot Mouthwash Study of Pioglitazone and Simvastatin in Healthy Volunteers
- Conditions
- Interventions
- First Posted Date
- 2007-09-19
- Last Posted Date
- 2017-10-05
- Lead Sponsor
- University Hospitals Cleveland Medical Center
- Target Recruit Count
- 25
- Registration Number
- NCT00531882
- Locations
- 🇺🇸
Rainbow Babies and Children's Hospital, Cleveland, Ohio, United States
🇺🇸University Hospitals of Cleveland, Cleveland, Ohio, United States
Cost-effectiveness of Two Painkillers for Treating Pain After Limb Injuries
- Conditions
- Interventions
- First Posted Date
- 2007-09-12
- Last Posted Date
- 2021-06-08
- Lead Sponsor
- Chinese University of Hong Kong
- Target Recruit Count
- 782
- Registration Number
- NCT00528658
- Locations
- 🇭🇰
Prince of Wales Hospital, Sha Tin, NT, Hong Kong
Acute Pediatric Fracture Analgesia Study
- First Posted Date
- 2007-08-24
- Last Posted Date
- 2008-03-07
- Lead Sponsor
- Medical College of Wisconsin
- Target Recruit Count
- 335
- Registration Number
- NCT00520442
- Locations
- 🇺🇸
Children's Hospital of Wisconsin, Milwaukee, Wisconsin, United States
Ibuprofen vs. Continuous Indomethacin in the Treatment of PDA
- Conditions
- First Posted Date
- 2007-06-12
- Last Posted Date
- 2011-07-21
- Lead Sponsor
- Shaare Zedek Medical Center
- Target Recruit Count
- 70
- Registration Number
- NCT00485160
- Locations
- 🇮🇱
Shaare Zedek Medical Center, Jerusalem, Israel
Acetaminophen Versus Ibuprofen for the Control of Immediate and Delayed Pain Following Orthodontic Separator Placement
- Conditions
- Interventions
- First Posted Date
- 2007-06-11
- Last Posted Date
- 2020-08-20
- Lead Sponsor
- University of Missouri, Kansas City
- Target Recruit Count
- 35
- Registration Number
- NCT00484744
- Locations
- 🇺🇸
Orthodontic office of Drs. Dan Blackwell, Beth Blackwell-Nill, Scott Francois, Lee's Summit, Missouri, United States
🇺🇸Orthodontic office of Dr. James Osborne, Lee's Summit, Missouri, United States
Comparison of Acetaminophen With Codeine and Ibuprofen for Children With Injuries
- Conditions
- First Posted Date
- 2007-05-17
- Last Posted Date
- 2007-05-17
- Lead Sponsor
- University of California, San Diego
- Target Recruit Count
- 68
- Registration Number
- NCT00474721
- Locations
- 🇺🇸
Rady Children's Hospital, San Diego, California, United States
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.