Ibuprofen
- Generic Name
- Ibuprofen
- Brand Names
- Addaprin, Advil, Advil Cold and Sinus, Advil Congestion Relief, Advil PM, Advil Sinus Congestion and Pain, Alivio, Caldolor, Cedaprin, Children's Ibuprofen, Diphen, Duexis, Ibu, Ibutab, Junior Strength Motrin, Motrin, Motrin PM, Neoprofen, Nuprin, Pedea, Proprinal, Reprexain, Sudafed PE Head Congestion Plus Pain, Vicoprofen, Wal-profen Congestion Relief and Pain, Ibuprofen Gen.Orph
- Drug Type
- Small Molecule
- Chemical Formula
- C13H18O2
- CAS Number
- 15687-27-1
- Unique Ingredient Identifier
- WK2XYI10QM
- Background
Ibuprofen is a non-steroidal anti-inflammatory drug (NSAID) derived from propionic acid and it is considered the first of the propionics. The formula of ibuprofen is 2-(4-isobutylphenyl) propionic acid and its initial development was in 1960 while researching for a safer alternative for aspirin. Ibuprofen was finally patented in 1961 and this drug was first ...
- Indication
Ibuprofen is the most commonly used and prescribed NSAID. It is a very common over-the-counter medication widely used as an analgesic, anti-inflammatory and antipyretic.
...
- Associated Conditions
- Acute Pain, Ankylosing Spondylitis (AS), Common Cold, Cystic Fibrosis (CF), Fever, Gastric Ulcer, Gout, Headache, Insomnia, Juvenile Idiopathic Arthritis (JIA), Menstrual Distress (Dysmenorrhea), Migraine, Mild pain, Nasal Congestion, Osteoarthritis (OA), Pain, Pain, Inflammatory, Patent Ductus Arteriosus (PDA), Pericarditis, Primary Dysmenorrhoea, Rheumatoid Arthritis, Severe Pain, Sinus pressure, Mild to moderate pain, Minor aches and pains, Moderate Pain
- Associated Therapies
- -
Comparing Ibuprofen And Indomethacin For The Treatment Of The Patent Ductus Arteriosus in Very Premature Babies
- Conditions
- Interventions
- First Posted Date
- 2007-05-08
- Last Posted Date
- 2015-09-02
- Lead Sponsor
- KK Women's and Children's Hospital
- Registration Number
- NCT00470743
- Locations
- 🇸🇬
KK Women's and Children's Hospital / National University Hospital, Singapore, Singapore
Efficacy and Safety Study of Caldolor (IV Ibuprofen) in Hospitalized Adult Orthopedic Patients
- First Posted Date
- 2007-05-08
- Last Posted Date
- 2015-08-21
- Lead Sponsor
- Cumberland Pharmaceuticals
- Target Recruit Count
- 185
- Registration Number
- NCT00470600
- Locations
- 🇺🇸
Research Concepts, Inc., Houston, Texas, United States
🇺🇸Southeastern Center for Clinical Trials, Atlanta, Georgia, United States
🇺🇸Clinical Management Services, Inc., Arcadia, California, United States
Myogenic and Osteogenic Responses to eXercise and Ibuprofen
- Conditions
- Interventions
- First Posted Date
- 2007-04-19
- Last Posted Date
- 2015-11-01
- Lead Sponsor
- University of Colorado, Denver
- Target Recruit Count
- 159
- Registration Number
- NCT00462722
- Locations
- 🇺🇸
University of Colorado Denver, Aurora, Colorado, United States
Efficacy and Safety Study of HZT-501 in Subjects Requiring Nonsteroidal Anti-Inflammatory Drug (NSAID) Treatment
- First Posted Date
- 2007-03-22
- Last Posted Date
- 2024-12-16
- Lead Sponsor
- Amgen
- Target Recruit Count
- 906
- Registration Number
- NCT00450216
Efficacy and Safety Study of HZT-501 in Reducing the Risk of Ibuprofen-associated Ulcers
- First Posted Date
- 2007-03-22
- Last Posted Date
- 2024-12-16
- Lead Sponsor
- Amgen
- Target Recruit Count
- 627
- Registration Number
- NCT00450658
Study To Determine The Effects Of Doses Of Relacatib On The Metabolism Of Acetaminophen, Ibuprofen And Atorvastatin
- Conditions
- Interventions
- First Posted Date
- 2006-12-13
- Last Posted Date
- 2017-10-04
- Lead Sponsor
- GlaxoSmithKline
- Target Recruit Count
- 32
- Registration Number
- NCT00411190
- Locations
- 🇧🇪
GSK Investigational Site, Liège, Belgium
Study to Determine if Taking OTC Non-Steroidal Anti-Inflammatory Affects Eye Pressure in Patients Using Glaucoma Drops
- Conditions
- Interventions
- First Posted Date
- 2006-11-22
- Last Posted Date
- 2018-04-04
- Lead Sponsor
- Philadelphia Eye Associates
- Target Recruit Count
- 51
- Registration Number
- NCT00402493
- Locations
- 🇺🇸
Philadelphia Eye Associates, Philadelphia, Pennsylvania, United States
Effectiveness Of Single Doses Of Ibuprofen In Patients With Osteoarthritis Of The Knee
- Conditions
- First Posted Date
- 2006-09-07
- Last Posted Date
- 2008-10-16
- Lead Sponsor
- GlaxoSmithKline
- Target Recruit Count
- 36
- Registration Number
- NCT00372801
- Locations
- 🇦🇺
GSK Investigational Site, Randwick, Sydney, New South Wales, Australia
Prospective Randomized Evaluation Of Celecoxib Integrated Safety Vs Ibuprofen Or Naproxen
- Conditions
- Interventions
- First Posted Date
- 2006-06-29
- Last Posted Date
- 2021-03-03
- Target Recruit Count
- 24081
- Registration Number
- NCT00346216
- Locations
- 🇺🇸
Orange County Research Center, Tustin, California, United States
🇺🇸AnMed Health, Anderson, South Carolina, United States
🇺🇸Wagdy W. Kades, MD, Inc., Los Angeles, California, United States
Drotaverine in Dysmenorrhoea Treatment
- Conditions
- Interventions
- First Posted Date
- 2006-02-16
- Last Posted Date
- 2017-08-08
- Lead Sponsor
- Sanofi
- Target Recruit Count
- 480
- Registration Number
- NCT00292747
- Locations
- 🇭🇺
Sanofi-Aventis, Budapest, Hungary
Drug Development Updates
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