Ibuprofen

Generic Name: Ibuprofen

Brand Names: Addaprin, Advil, Advil Cold and Sinus, Advil Congestion Relief, Advil PM, Advil Sinus Congestion and Pain, Alivio, Caldolor, Cedaprin, Children's Ibuprofen, Diphen, Duexis, Ibu, Ibutab, Junior Strength Motrin, Motrin, Motrin PM, Neoprofen, Nuprin, Pedea, Proprinal, Reprexain, Sudafed PE Head Congestion Plus Pain, Vicoprofen, Wal-profen Congestion Relief and Pain, Ibuprofen Gen.Orph

Drug Type: Small Molecule

Chemical Formula: C_₁₃H_₁₈O_₂

CAS Number: 15687-27-1

Unique Ingredient Identifier: WK2XYI10QM

Background: Ibuprofen is a non-steroidal anti-inflammatory drug (NSAID) derived from propionic acid and it is considered the first of the propionics. The formula of ibuprofen is 2-(4-isobutylphenyl) propionic acid and its initial development was in 1960 while researching for a safer alternative for aspirin. Ibuprofen was finally patented in 1961 and this drug was first ...

Indication: Ibuprofen is the most commonly used and prescribed NSAID. It is a very common over-the-counter medication widely used as an analgesic, anti-inflammatory and antipyretic.
...

Associated Conditions: Acute Pain, Ankylosing Spondylitis (AS), Common Cold, Cystic Fibrosis (CF), Fever, Gastric Ulcer, Gout, Headache, Insomnia, Juvenile Idiopathic Arthritis (JIA), Menstrual Distress (Dysmenorrhea), Migraine, Mild pain, Nasal Congestion, Osteoarthritis (OA), Pain, Pain, Inflammatory, Patent Ductus Arteriosus (PDA), Pericarditis, Primary Dysmenorrhoea, Rheumatoid Arthritis, Severe Pain, Sinus pressure, Mild to moderate pain, Minor aches and pains, Moderate Pain

Associated Therapies: -

Clinical Trials

Ibuprofen Alone and in Combination With Acetaminophen for Treatment of Fever

Phase 4

Completed

Conditions: Fever

Interventions: Drug: Acetaminophen
Drug: Ibuprofen

First Posted Date: 2005-12-20

Last Posted Date: 2012-05-09

Lead Sponsor: Penn State University

Target Recruit Count: 60

Registration Number: NCT00267293

Locations: 🇺🇸
Penn State Milton S. Hershey Medical Center, Hershey, Pennsylvania, United States

Effects of Pretreatment With Ibuprofen in Post-Electroconvulsive Therapy (ECT) Headache

Not Applicable

Withdrawn

Conditions: Mental Disorders

First Posted Date: 2005-11-28

Last Posted Date: 2012-09-25

Lead Sponsor: Norwegian University of Science and Technology

Registration Number: NCT00258791

Use of Ibuprofen to Prevent IUD Site Effects

Phase 3

Completed

Conditions: IUD Removal

First Posted Date: 2005-10-25

Last Posted Date: 2006-10-17

Lead Sponsor: FHI 360

Target Recruit Count: 2019

Registration Number: NCT00243815

Locations: 🇨🇱
43 Ministry of Health facilities, Santiago, Chile

An Effectiveness and Safety Study of Acetaminophen 1000 mg and Ibuprofen 400 mg in Postoperative Dental Pain.

Phase 4

Completed

Conditions: Pain

Interventions: Drug: Acetaminophen
Drug: Ibuprofen
Drug: Placebo

First Posted Date: 2005-10-18

Last Posted Date: 2015-06-19

Lead Sponsor: Johnson & Johnson Consumer and Personal Products Worldwide

Target Recruit Count: 222

Registration Number: NCT00240825

An Effectiveness and Safety Study of Acetaminophen 1000 mg and Ibuprofen 400 mg in Postoperative Dental Pain

Phase 4

Completed

Conditions: Pain

Interventions: Drug: placebo
Drug: acetaminophen
Drug: ibuprofen

First Posted Date: 2005-10-18

Last Posted Date: 2015-06-19

Lead Sponsor: Johnson & Johnson Consumer and Personal Products Worldwide

Target Recruit Count: 224

Registration Number: NCT00240864

BONSAI: Biomarkers of Nonsteroidal Anti-Inflammatories

Phase 1

Conditions: Alzheimer's Disease

Interventions: Drug: Placebo
Drug: Ibuprofen

First Posted Date: 2005-10-17

Last Posted Date: 2009-04-29

Lead Sponsor: National Institute on Aging (NIA)

Target Recruit Count: 40

Registration Number: NCT00239746

Locations: 🇺🇸
Layton Aging & Alzheimer's Disease Center, Portland, Oregon, United States

A Study of Caldolor in Hospitalized Febrile Pediatric Patients

Phase 3

Completed

Conditions: Fever

First Posted Date: 2005-09-26

Last Posted Date: 2010-04-12

Lead Sponsor: Cumberland Pharmaceuticals

Registration Number: NCT00225706

Locations: 🇿🇦
Unitas Hospital, Lyttleton, Pretoria, South Africa
🇺🇸
Vanderbilt University Children's Hospital, Nashville, Tennessee, United States
🇵🇦
Hospital Cecilio Castillero, Chitre, Herrera, Panama

Ibuprofen and Renal Function in Premature Infants

Phase 4

Completed

Conditions: Premature Infants
Patent Ductus Arteriosus

First Posted Date: 2005-09-22

Last Posted Date: 2006-09-19

Lead Sponsor: Maternite Regionale Universitaire

Target Recruit Count: 120

Registration Number: NCT00217191

Locations: 🇫🇷
CHU, Dijon, France
🇫🇷
AP-HM (Néonatologie), Marseille, France
🇫🇷
Maternite Regionale Universitaire, Nancy, France

Treatment of Orthostatic Hypotension in Autonomic Failure

First Posted Date: 2005-09-22

Last Posted Date: 2017-01-18

Lead Sponsor: Vanderbilt University

Target Recruit Count: 389

Registration Number: NCT00223691

Locations: 🇺🇸
Vanderbilt University, Nashville, Tennessee, United States

Assessment of Inflammatory Mediators (AIM)

Not Applicable

Completed

Conditions: Cystic Fibrosis

First Posted Date: 2005-09-22

Last Posted Date: 2007-12-25

Lead Sponsor: Ramsey, Bonnie, MD

Target Recruit Count: 120

Registration Number: NCT00219895

Locations: 🇺🇸
Washington University - St. Louis Children's Hospital, St. Louis, Missouri, United States
🇺🇸
University of Alabama at Birmingham, Birmingham, Alabama, United States
🇺🇸
University of California - San Diego, San Diego, California, United States

and more 13 locations

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