Lidocaine

Generic Name: Lidocaine

Brand Names: Agoneaze, Akten, Alivio, Anestacon, Anodyne Lpt, Astero, Band-aid Hurt-free, Cathejell, Curacaine, Depo-medrol With Lidocaine, Dermacinrx Lido V Pak, Dermacinrx Phn Pak, Dermacinrx Prikaan, Diphen, Emla, Fortacin, Glydo, Instillagel, Kenalog, Lido Bdk, Lido-prilo Caine Pack, Lidocan, Lidodan, Lidoderm, Lidopac, Lidopril, Lidopro, Lidosol, Lidothol, Lidotral, Lignospan, Marcaine, Max-freeze, Medi-derm With Lidocaine, Neo-bex, Octocaine, Octocaine With Epinephrine, Oraqix, P-care, P-care X, Pliaglis, Prilolid, Prizotral, Procomycin, Readysharp Anesthetics Plus Ketorolac, Readysharp-A, Readysharp-p40, Readysharp-p80, Relador, Synera, Triple Antibiotic, Venipuncture Px1, Viadur, Xylocaine, Xylocaine With Epinephrine, Xylocard, Xylonor, Zingo, Ztlido

Drug Type: Small Molecule

Chemical Formula: C_₁₄H_₂₂N_₂O

CAS Number: 137-58-6

Unique Ingredient Identifier: 98PI200987

Background: Ever since its discovery and availability for sale and use in the late 1940s, lidocaine has become an exceptionally commonly used medication . In particular, lidocaine's principal mode of action in acting as a local anesthetic that numbs the sensations of tissues means the agent is indicated for facilitating local anesthesia for a large variety of surgical p...

Indication: Lidocaine is an anesthetic of the amide group indicated for production of local or regional anesthesia by infiltration techniques such as percutaneous injection and intravenous regional anesthesia by peripheral nerve block techniques such as brachial plexus and intercostal and by central neural techniques such as lumbar and caudal epidural blocks .

Associated Conditions: Acute Otitis Media (AOM), Anorectal discomfort, Arrhythmia, Back Pain Lower Back, Bacterial Vaginosis (BV), Burns, Cervical Syndrome, Earache, Fissure;Anal, Haemorrhoids, Infection, Inflammatory Reaction caused by ear infection-not otherwise specified, Insect Bites, Joint Pain, Mixed Vaginal Infections, Multiple Myeloma (MM), Myringitis, Neuritis, Osteolysis caused by Bone Tumors, Osteoporosis, Otitis Externa, Pain caused by ear infection-not otherwise specified, Pain, Inflammatory, Postherpetic Neuralgia, Primary Hyperparathyroidism (PHPT), Rheumatic Diseases, Rheumatic Joint Disease, Sciatica, Skin Irritation, Soft Tissue Inflammation, Sore Throat, Sunburn, Susceptible infections, Trichomonas Vaginitis, Ulcers, Leg, Urethral Strictures, Ventricular Arrhythmia, Vulvovaginal Candidiasis, Abrasions, Anal discomfort, Cutaneous lesions, Gum pain, Minor burns, Superficial Wounds, Susceptible Bacterial Infections, Ulceration of the mouth, Viral infections of the external ear canal

Associated Therapies: Local Anaesthesia therapy, Post Myocardial Infarction Treatment, Regional Anesthesia therapy

Clinical Trials

Analgetic Effect of Two Solutions of Intracameral Anesthesia During Cataract Surgery in Patients

Completed

Conditions: Cataract
Ophthalmological Disorder
Analgesia

Interventions: Drug: lignocaine
Procedure: Phacoemulsyfication
Procedure: Intraocular lens implantation
Behavioral: Visual Analog Scale for Pain
Behavioral: Brief Pain Inventory-short form
Diagnostic Test: Best corrected visual acuity measurment
Diagnostic Test: Slit-lamp biomicroscopy

First Posted Date: 2019-11-18

Last Posted Date: 2019-11-18

Lead Sponsor: Medical University of Lublin

Target Recruit Count: 62

Registration Number: NCT04166578

Locations: 🇵🇱
General Department of Ophthalmology in Lublin, Lublin, Poland

Comparison Of Dexmedetomidine, Fentanyl And Lignocaine In Attenuation Of Hemodynamic Response To Direct Laryngoscopy And Intubation In Patient Undergoing Laparoscopic Cholecystectomy

Not Applicable

Conditions: Laparoscopic Cholecystectomy

Interventions: Drug: fentanyl
Drug: lidocaine
Drug: dexmedetomidine

First Posted Date: 2019-10-24

Last Posted Date: 2020-02-07

Lead Sponsor: Sana Urooj

Target Recruit Count: 30

Registration Number: NCT04138472

Locations: 🇵🇰
DUHS, Civil hospital Karachi (CHK), Karachi, Sindh, Pakistan

Pharmacodynamic Study of BIIB095 and BIIB074 in Healthy Participants and Participants With Painful Diabetic Polyneuropathy

Phase 1

Withdrawn

Conditions: Healthy Volunteers
Diabetic Neuropathies

Interventions: Drug: BIIB095
Drug: Placebo
Drug: Lidocaine
Drug: BIIB074

First Posted Date: 2019-09-26

Last Posted Date: 2021-03-22

Lead Sponsor: Biogen

Registration Number: NCT04106050

Sphenopalatine Ganglion Block to Treat Shoulder Pain After Laparoscopic Surgery

Not Applicable

Conditions: Nerve Block

Interventions: Drug: Saline Solution
Drug: Lidocaine

First Posted Date: 2019-09-24

Last Posted Date: 2019-09-24

Lead Sponsor: Rabin Medical Center

Target Recruit Count: 76

Registration Number: NCT04101019

Locations: 🇮🇱
Beilinson hospital, Petach tikvah, Israel

Perioperative Lidocaine and Ketamine in Abdominal Surgery

Phase 3

Active, not recruiting

Conditions: Postoperative Pain

Interventions: Drug: Lidocaine and ketamine
Drug: Placebo
Drug: Lidocaine
Drug: Ketamine

First Posted Date: 2019-09-10

Last Posted Date: 2024-06-06

Lead Sponsor: The Cleveland Clinic

Target Recruit Count: 420

Registration Number: NCT04084548

Locations: 🇺🇸
Cleveland Clinic Florida, Weston, Florida, United States

Propofol and Magnesium Sulfate Intravenous Infusion During Endoscopic Sinus Surgery

Not Applicable

Conditions: Endoscopic Sinus Surgery

Interventions: Drug: Propofol infusion
Drug: Magnesium Sulfate infusion
Drug: Lidocaine
Drug: Fentanyl
Drug: Propofol
Drug: Atracurium
Procedure: Mechanical Ventilation

First Posted Date: 2019-09-06

Last Posted Date: 2019-09-06

Lead Sponsor: Mansoura University

Target Recruit Count: 50

Registration Number: NCT04078659

Locations: 🇪🇬
Nabil A Abd El-Mageed, Mansoura, DK, Egypt

IV Lidocaine Analgesia in Pediatric Scoliosis Surgery

Phase 3

Completed

Conditions: Scoliosis; Adolescence
Anesthesia Recovery Period

Interventions: Drug: Lidocaine
Drug: Saline Solution

First Posted Date: 2019-08-28

Last Posted Date: 2024-05-14

Lead Sponsor: University of British Columbia

Target Recruit Count: 48

Registration Number: NCT04069169

Locations: 🇨🇦
BC Children's Hospital - Department of Anesthesia, Vancouver, British Columbia, Canada

Effect of Perioperative Intravenous Lidocaine Infusion on Postoperative Recovery in Patients Undergoing Arthroscopic Rotator Cuff Repair Under General Anesthesia

Not Applicable

Completed

Conditions: Rotator Cuff Tears

Interventions: Drug: Normal saline
Drug: Lidocaine

First Posted Date: 2019-08-19

Last Posted Date: 2019-08-19

Lead Sponsor: Yonsei University

Target Recruit Count: 98

Registration Number: NCT04061057

Locations: 🇰🇷
Department of Anesthesiology and Pain Medicine, Anesthesia and Pain Research Institue, Yonsei Universiy College of Medicine, Seoul, Korea, Republic of