Methylene blue
- Generic Name
- Methylene blue
- Brand Names
- Hyophen, Phosphasal, Provayblue, Proveblue, Urelle, Uribel, Urimar Reformulated Oct 2013, Urin DS, Urogesic Blue Reformulated Apr 2012, Ustell, Utira, Lumeblue (previously known as Methylthioninium chloride Cosmo), Methylthioninium chloride Proveblue
- Drug Type
- Small Molecule
- Chemical Formula
- C16H18ClN3S
- CAS Number
- 61-73-4
- Unique Ingredient Identifier
- 8NAP7826UB
- Background
Methylene blue is an oxidation-reduction agent. The intravenous form of methylene blue is approved by the FDA for the treatment of pediatric and adult patients with acquired methemoglobinemia. Historically, it has been widely used in Africa to treat malaria, but now it disappeared when chloroquine (CQ) and other drugs entered the market. Its use as an urinar...
- Indication
Indicated for the treatment of pediatric and adult patients with acquired methemoglobinemia.
...
- Associated Conditions
- Cystitis, Methemoglobinemia, Nephritis, Urethritis, Urinary tract inflammation
- Associated Therapies
- Diuresis
Sentinel Lymph Node Biopsy in Breast Cancer Surgery Using ICG
- Conditions
- Interventions
- First Posted Date
- 2018-07-09
- Last Posted Date
- 2021-08-04
- Lead Sponsor
- Chinese Academy of Sciences
- Target Recruit Count
- 130
- Registration Number
- NCT03579979
- Locations
- 🇨🇳
Key Laboratory of Molecular Imaging, Chinese Academy of Sciences, Beijing, Beijing, China
Acquired Methemoglobinemia Observational Registry
- First Posted Date
- 2018-05-31
- Last Posted Date
- 2023-04-12
- Lead Sponsor
- Hospital Quality Foundation
- Target Recruit Count
- 24
- Registration Number
- NCT03542760
- Locations
- 🇺🇸
UT Southwestern, Dallas, Texas, United States
🇺🇸University of Pittsburgh, Pittsburgh, Pennsylvania, United States
🇺🇸University of Kansas Health System, Kansas City, Kansas, United States
MOM's PAIN (Methylene Blue for Oral Mucositis' PAIN)
- Conditions
- Interventions
- First Posted Date
- 2018-03-19
- Last Posted Date
- 2023-04-25
- Lead Sponsor
- M.D. Anderson Cancer Center
- Target Recruit Count
- 69
- Registration Number
- NCT03469284
- Locations
- 🇺🇸
M D Anderson Cancer Center, Houston, Texas, United States
Hemodynamic Effects of Methylene Blue vs Hydroxocobalamin in Patients at Risk of Vasoplegia During Cardiac Surgery
- Conditions
- Interventions
- First Posted Date
- 2018-02-27
- Last Posted Date
- 2020-03-02
- Lead Sponsor
- Dartmouth-Hitchcock Medical Center
- Registration Number
- NCT03446599
- Locations
- 🇺🇸
Dartmouth-Hitchcock, Lebanon, New Hampshire, United States
Pre-treatment With Methylene Blue Prevent Peri-operative Reduced Systemic Vascular Resistance
- First Posted Date
- 2018-01-23
- Last Posted Date
- 2018-01-23
- Lead Sponsor
- Southwest Hospital, China
- Target Recruit Count
- 70
- Registration Number
- NCT03406676
- Locations
- 🇨🇳
Southwest Hospital, Chongqing, Chongqing, China
MEthylene Blue In Patients With Acquired Methemoglobinemia
- First Posted Date
- 2018-01-10
- Last Posted Date
- 2023-04-10
- Lead Sponsor
- Provepharm SAS
- Target Recruit Count
- 7
- Registration Number
- NCT03395223
- Locations
- 🇫🇷
Hôpital Lariboisière, Paris, France
Dose Parameters for Photodynamic Therapy on Periodontal Disease
- Conditions
- Interventions
- First Posted Date
- 2017-08-25
- Last Posted Date
- 2017-08-25
- Lead Sponsor
- University of Nove de Julho
- Target Recruit Count
- 30
- Registration Number
- NCT03262077
Fluorescent Imaging & Methylene Blue: Ureter Study
- Conditions
- Interventions
- First Posted Date
- 2017-06-06
- Last Posted Date
- 2017-06-06
- Lead Sponsor
- University of Oxford
- Target Recruit Count
- 50
- Registration Number
- NCT03177070
- Locations
- 🇬🇧
Oxford University Hospitals NHS Foundation Trust, Oxford, Oxfordshire, United Kingdom
Evaluating in Cirrhotics With Refractory Vasoplegia the Effect of Methylene Blue
- Conditions
- Interventions
- First Posted Date
- 2017-04-19
- Last Posted Date
- 2018-01-30
- Lead Sponsor
- Institute of Liver and Biliary Sciences, India
- Target Recruit Count
- 111
- Registration Number
- NCT03120637
- Locations
- 🇮🇳
Liver Coma ICU, Institute of Liver and Biliary Sciences, New Delhi, Delhi, India
What Should be the Next Vasopressor for Severe Septic Shock? Methylene Blue or Terlipressin
- First Posted Date
- 2017-01-31
- Last Posted Date
- 2018-08-29
- Lead Sponsor
- Ramathibodi Hospital
- Target Recruit Count
- 60
- Registration Number
- NCT03038503
- Locations
- 🇹🇭
Ramathibodi hospital, Bangkok, Thailand
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.