Glucose
- Generic Name
- Glucose
- Brand Names
- Bss Ophthalmic Solution, Citrasate, Clinimix 2.75/5, Clinimix E 2.75/5, Dextroject, Dianeal, H.E.L.P.bicel, Hemosate Ultra, Lactate 1-2-3, Leukotrap, Naturalyte, Nauzene, Normosol-R, Nxstage Pureflow, Olimel, Periolimel, Physioneal 40, Sag-M, Sclerodex, Selectbag One
- Drug Type
- Small Molecule
- Unique Ingredient Identifier
- IY9XDZ35W2
- Background
Glucose is a simple sugar (monosaccharide) generated during phosynthesis involving water, carbon and sunlight in plants. It is produced in humans via hepatic gluconeogenesis and breakdown of polymeric glucose forms (glycogenolysis). It circulates in human circulation as blood glucose and acts as an essential energy source for many organisms through aerobic or anaerobic respiration and fermentation. It is primarily stored as starch in plants and glycogen in animals to be used in various metabolic processes in the cellular level. Its aldohexose stereoisomer, dextrose or D-glucose, is the most commonly occurring isomer of glucose in nature. L-glucose is a synthesized enantiomer that is used as a low-calorie sweetener and laxative. The unspecified form of glucose is commonly supplied as an injection for nutritional supplementation or metabolic disorders where glucose levels are improperly regulated. Glucose is listed on the World Health Organization's List of Essential Medicines.
- Indication
Glucose pharmaceutical formulations (oral tablets, injections) are indicated for caloric supply and carbohydrate supplementation in case of nutrient deprivation. It is also used in metabolic disorders such as hypoglycemia.
- Associated Conditions
- Arrhythmia, Caloric Deficit, Edema of the cerebrum, Hypoglycemia, Metabolic Alkalosis
- Associated Therapies
- Blood Specimen Collection, Electrolyte replacement, Nutritional supplementation, Parenteral Nutrition, Parenteral rehydration therapy, Plasmapheresis, Positive cardiac inotropic effect, Total parenteral nutrition therapy, Urine alkalinization therapy, Fluid and electrolyte maintenance therapy
The Impact of a Preoperative Nerve Block on the Consumption of Sevoflurane in Total Shoulder Arthroplasty
- Conditions
- Rotator Cuff InjuriesAnesthesia; Functional
- Interventions
- First Posted Date
- 2019-07-16
- Last Posted Date
- 2024-06-06
- Lead Sponsor
- University of Alberta
- Target Recruit Count
- 17
- Registration Number
- NCT04020601
- Locations
- 🇨🇦
University of Alberta Hospital, Edmonton, Alberta, Canada
The Impact of an Epidural Anesthetic on the Consumption of Sevoflurane in Major Abdominal Surgery
- Conditions
- Liver DiseasesBowel DiseaseAnesthesia; FunctionalPancreas Disease
- Interventions
- Drug: Ropivacaine-SufentanilDrug: Dextrose 5
- First Posted Date
- 2019-07-16
- Last Posted Date
- 2022-05-27
- Lead Sponsor
- University of Alberta
- Registration Number
- NCT04021264
- Locations
- 🇨🇦
University of Alberta Hospital, Edmonton, Alberta, Canada
Dextrose, Corticosteroids and Surgical Release in Carpal Tunnel Syndrome
- Conditions
- Peripheral Nervous System DiseasesNerve Compression SyndromesCarpal Tunnel Syndrome
- Interventions
- Drug: Corticosteroid vs. DextroseProcedure: Corticosteroid or Dextrose vs. Surgery
- First Posted Date
- 2019-07-10
- Last Posted Date
- 2021-03-11
- Lead Sponsor
- University Medical Centre Ljubljana
- Target Recruit Count
- 100
- Registration Number
- NCT04014244
- Locations
- 🇸🇮
University Medical Center Ljubljana, Department of Neurology, Institute of Clinical Neurophysiology, Ljubljana, Slovenia
Intravenous N-acetylcysteine and Oseltamivir Versus Oseltamivir in Adults Hospitalized With Influenza and Pneumonia
- First Posted Date
- 2019-04-03
- Last Posted Date
- 2023-11-27
- Lead Sponsor
- Chinese University of Hong Kong
- Target Recruit Count
- 160
- Registration Number
- NCT03900988
- Locations
- 🇭🇰
Prince of Wales Hospital, Hong Kong, Hong Kong
Effects of Oral Glucose and Teduglutide on Plasma Lipoproteins
- Conditions
- Hyperlipidemias
- Interventions
- Drug: TED + glucose
- First Posted Date
- 2019-03-04
- Last Posted Date
- 2021-04-29
- Lead Sponsor
- University Health Network, Toronto
- Target Recruit Count
- 15
- Registration Number
- NCT03860688
- Locations
- 🇨🇦
Tornto General Hospital, UHN, Toronto, Ontario, Canada
Effect of Different Intravenous Fluids on Post-operative Chronic Subdural Hematoma Size and Recurrence
- Conditions
- Chronic Subdural Hematoma
- Interventions
- Drug: Dextrose 5% W/ Sodium Chloride 0.225%
- First Posted Date
- 2019-02-06
- Last Posted Date
- 2020-10-08
- Lead Sponsor
- Carilion Clinic
- Target Recruit Count
- 35
- Registration Number
- NCT03831997
- Locations
- 🇺🇸
Carilion Roanoke Memorial Hospital, Roanoke, Virginia, United States
Vitamin C Infusion for TReatment in Sepsis and Alcoholic Hepatitis
- Conditions
- Alcoholic HepatitisSepsis
- Interventions
- Drug: Dextrose 5% in water
- First Posted Date
- 2019-02-04
- Last Posted Date
- 2023-08-28
- Lead Sponsor
- Virginia Commonwealth University
- Target Recruit Count
- 20
- Registration Number
- NCT03829683
- Locations
- 🇺🇸
Virginia Commonwealth University, Richmond, Virginia, United States
Individual Differences in Drug Response
- Conditions
- Differential Female Response to Δ9-tetrahydrocannabinol (THC)
- Interventions
- First Posted Date
- 2019-01-18
- Last Posted Date
- 2024-07-03
- Lead Sponsor
- University of Chicago
- Target Recruit Count
- 60
- Registration Number
- NCT03809546
- Locations
- 🇺🇸
University of Chicago, Chicago, Illinois, United States
DIA_CENTRAL:T2D Treatment Pattern in Central Europe
- Conditions
- Diabetes Mellitus, Type 2
- Interventions
- Drug: Sodium Glucose Transporter 2 inhibitorDrug: Dipeptidyl-peptidase 4 inhibitor
- First Posted Date
- 2019-01-17
- Last Posted Date
- 2023-12-01
- Lead Sponsor
- Boehringer Ingelheim
- Target Recruit Count
- 4083
- Registration Number
- NCT03807440
- Locations
- 🇷🇺
Penza regional clinical hospital named after N.N. Burdenko, Center Nr.: 70095, Penza, Russian Federation
🇧🇬MC "Diamedical 2013" OOD, Center Nr.: 35902, Dimitrovgrad, Bulgaria
🇧🇬"Medical Center-Razgrad"OOD, Center Nr.: 35910, Razgrad, Bulgaria
Betamethasone (Betapred®) as Premedication for Reducing Postoperative Vomiting and Pain After Tonsillectomy
- Conditions
- TonsillectomyPainPONVBleeding
- Interventions
- Drug: 10% glucose solution
- First Posted Date
- 2018-12-20
- Last Posted Date
- 2024-05-14
- Lead Sponsor
- Umeå University
- Target Recruit Count
- 100
- Registration Number
- NCT03783182
- Locations
- 🇸🇪
Sunderby sjukhus, Luleå, Sweden
Drug Development Updates
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