Glucose

Generic Name: Glucose

Brand Names: Bss Ophthalmic Solution, Citrasate, Clinimix 2.75/5, Clinimix E 2.75/5, Dextroject, Dianeal, H.E.L.P.bicel, Hemosate Ultra, Lactate 1-2-3, Leukotrap, Naturalyte, Nauzene, Normosol-R, Nxstage Pureflow, Olimel, Periolimel, Physioneal 40, Sag-M, Sclerodex, Selectbag One

Drug Type: Small Molecule

Unique Ingredient Identifier: IY9XDZ35W2

Background: Glucose is a simple sugar (monosaccharide) generated during phosynthesis involving water, carbon and sunlight in plants. It is produced in humans via hepatic gluconeogenesis and breakdown of polymeric glucose forms (glycogenolysis). It circulates in human circulation as blood glucose and acts as an essential energy source for many organisms through aerobic or anaerobic respiration and fermentation. It is primarily stored as starch in plants and glycogen in animals to be used in various metabolic processes in the cellular level. Its aldohexose stereoisomer, dextrose or D-glucose, is the most commonly occurring isomer of glucose in nature. L-glucose is a synthesized enantiomer that is used as a low-calorie sweetener and laxative. The unspecified form of glucose is commonly supplied as an injection for nutritional supplementation or metabolic disorders where glucose levels are improperly regulated. Glucose is listed on the World Health Organization's List of Essential Medicines.

Indication: Glucose pharmaceutical formulations (oral tablets, injections) are indicated for caloric supply and carbohydrate supplementation in case of nutrient deprivation. It is also used in metabolic disorders such as hypoglycemia.

Associated Conditions: Arrhythmia, Caloric Deficit, Edema of the cerebrum, Hypoglycemia, Metabolic Alkalosis

Associated Therapies: Blood Specimen Collection, Electrolyte replacement, Nutritional supplementation, Parenteral Nutrition, Parenteral rehydration therapy, Plasmapheresis, Positive cardiac inotropic effect, Total parenteral nutrition therapy, Urine alkalinization therapy, Fluid and electrolyte maintenance therapy

Clinical Trials

Lactate and Glycerol Contribution to Gluconeogenesis

Phase 1

Not yet recruiting

Conditions: Type 2 Diabetes
Obesity
Healthy

Interventions: Drug: Glycerol
Drug: Glucose
Drug: Lactate

First Posted Date: 2025-05-02

Last Posted Date: 2025-05-13

Lead Sponsor: Rutgers, The State University of New Jersey

Target Recruit Count: 48

Registration Number: NCT06955130

Preoperative Two Hours Carbohydrate Load On Pediatric Patient Undergoing Elective Surgery

Not Applicable

Completed

Conditions: Preoperative
Carbohydrate
Pediatric
Elective Surgery

Interventions: Other: Apple juice
Drug: Anhydrous glucose
Other: Water

First Posted Date: 2025-02-19

Last Posted Date: 2025-02-19

Lead Sponsor: Tanta University

Target Recruit Count: 90

Registration Number: NCT06833671

Locations: 🇪🇬
Tanta University, Tanta, El-Gharbia, Egypt

Effects of Dextrose Versus Saline Infusion on Intrathecal Morphine-Induced Postoperative Nausea and Vomiting During Gynecological Abdominal Surgeries: Randomized Controlled Double-blind Study

Phase 4

Not yet recruiting

Conditions: Gynecological Abdominal Surgeries

Interventions: Drug: 0.9% saline
Drug: dextrose 5%
Drug: Dextrose 10%

First Posted Date: 2024-12-10

Last Posted Date: 2024-12-10

Lead Sponsor: Assiut University

Target Recruit Count: 63

Registration Number: NCT06726980

Ceftriaxone Pulse Dose for Post-Treatment Lyme Disease

Early Phase 1

Recruiting

Conditions: Post-Treatment Lyme Disease

Interventions: Drug: Dextrose 5% (D5W)
Drug: Ceftriaxone (Rocephin®)

First Posted Date: 2024-09-24

Last Posted Date: 2025-02-14

Lead Sponsor: State University of New York - Upstate Medical University

Target Recruit Count: 44

Registration Number: NCT06611111

Locations: 🇺🇸
SUNY Upstate Medical University, Upstate Global Health Institute, East Syracuse, New York, United States

Evaluate the Efficacy and Safety of Amino Acid (15) Peritoneal Dialysis Solution in Peritoneal Dialysis Patients with Malnutrition.

Phase 4

Recruiting

Conditions: End Stage Renal Disease (ESRD)

Interventions: Drug: amino acid (15) peritoneal dialysis solution
Drug: glucose peritoneal dialysis solution

First Posted Date: 2024-09-19

Last Posted Date: 2024-12-30

Lead Sponsor: Chengdu Qingshan Likang Pharmaceutical Co., Ltd

Target Recruit Count: 400

Registration Number: NCT06597201

Locations: 🇨🇳
The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China
🇨🇳
Peking University People&'s Hospital, Beijing, Beijing, China
🇨🇳
Wuhan NO.1 Hospital, Wuhan, Hubei, China

and more 18 locations

Assessing Brain Metabolism Using MRS With Deuterated Glucose

Active, not recruiting

Conditions: Glioma

Interventions: Drug: Deuterated Glucose
Procedure: Magnetic Resonance Imaging (MRI)
Procedure: Blood Sample
Procedure: MR spectroscopy (MRS)

First Posted Date: 2024-09-13

Last Posted Date: 2024-09-13

Lead Sponsor: University of California, San Francisco

Target Recruit Count: 80

Registration Number: NCT06594315

Locations: 🇺🇸
University of California, San Francisco, San Francisco, California, United States

A DDI Study to Investigate PK and Safety of Cefiderocol in Combination With Xeruborbactam in Healthy Adult Participants

Phase 1

Recruiting

Conditions: Bacterial Infections

Interventions: Drug: Dextrose 5% in water
Drug: Xeruborbactam
Drug: Cefiderocol
Drug: Xeruborbactam/Cefiderocol

First Posted Date: 2024-08-09

Last Posted Date: 2025-02-25

Lead Sponsor: Qpex Biopharma, Inc.

Target Recruit Count: 40

Registration Number: NCT06547554

Locations: 🇺🇸
Minneapolis Clinic, Minneapolis, Minnesota, United States

Fascia Iliaca Block for Postoperative Pain Control After Elective Hip Arthroplasty

Not Applicable

Not yet recruiting

Conditions: Hip Osteoarthritis

Interventions: Drug: Naropin, 0.2% Injectable Solution in Sodium chloride
Drug: Naropin, 0.2% Injectable Solution in dextrose 5%
Drug: Dextrose 10 % in Water

First Posted Date: 2024-08-02

Last Posted Date: 2024-08-02

Lead Sponsor: Foisor Orthopedics Clinical Hospital

Target Recruit Count: 210

Registration Number: NCT06534697

Comparing the Gastric Emptying Times of Underweight and Healthy-weight School-aged Children

Not Applicable

Recruiting

Conditions: Preoperative Fasting

Interventions: Drug: %5 Dextrose

First Posted Date: 2024-07-26

Last Posted Date: 2024-07-31

Lead Sponsor: Karaman Training and Research Hospital

Target Recruit Count: 60

Registration Number: NCT06522204

Locations: 🇹🇷
Karaman Training and Research Hospital, Karaman, Turkey

Observational Study of the Use of Extraneal in Peritoneal Dialysis in Patients

Recruiting

Conditions: Chronic Renal Failure

Interventions: Drug: Icodextrin Peritoneal Dialysis Solution
Drug: Glucose Peritoneal Dialysis Solution

First Posted Date: 2024-07-09

Last Posted Date: 2025-03-18

Lead Sponsor: Vantive Health LLC

Target Recruit Count: 889

Registration Number: NCT06492031

Locations: 🇨🇳
Beijing Haidian Hospital, Beijing, China
🇨🇳
Hangzhou Hospital Of Traditional Chinese Medicine, Hangzhou, China
🇨🇳
The Affiliated Hospital of Inner Mongolia Medical University, Hohhot, China

and more 7 locations

Drug Development Updates

Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.

Home Terms & Conditions Privacy Policy