Glucose

Generic Name: Glucose

Brand Names: Bss Ophthalmic Solution, Citrasate, Clinimix 2.75/5, Clinimix E 2.75/5, Dextroject, Dianeal, H.E.L.P.bicel, Hemosate Ultra, Lactate 1-2-3, Leukotrap, Naturalyte, Nauzene, Normosol-R, Nxstage Pureflow, Olimel, Periolimel, Physioneal 40, Sag-M, Sclerodex, Selectbag One

Drug Type: Small Molecule

Chemical Formula: -

CAS Number: -

Unique Ingredient Identifier: IY9XDZ35W2

Background: Glucose is a simple sugar (monosaccharide) generated during phosynthesis involving water, carbon and sunlight in plants. It is produced in humans via hepatic gluconeogenesis and breakdown of polymeric glucose forms (glycogenolysis). It circulates in human circulation as blood glucose and acts as an essential energy source for many organisms through aerobic or anaerobic respiration and fermentation. It is primarily stored as starch in plants and glycogen in animals to be used in various metabolic processes in the cellular level. Its aldohexose stereoisomer, dextrose or D-glucose, is the most commonly occurring isomer of glucose in nature. L-glucose is a synthesized enantiomer that is used as a low-calorie sweetener and laxative. The unspecified form of glucose is commonly supplied as an injection for nutritional supplementation or metabolic disorders where glucose levels are improperly regulated. Glucose is listed on the World Health Organization's List of Essential Medicines.

Indication: Glucose pharmaceutical formulations (oral tablets, injections) are indicated for caloric supply and carbohydrate supplementation in case of nutrient deprivation. It is also used in metabolic disorders such as hypoglycemia.

Associated Conditions: Arrhythmia, Caloric Deficit, Edema of the cerebrum, Hypoglycemia, Metabolic Alkalosis

Associated Therapies: Blood Specimen Collection, Electrolyte replacement, Nutritional supplementation, Parenteral Nutrition, Parenteral rehydration therapy, Plasmapheresis, Positive cardiac inotropic effect, Total parenteral nutrition therapy, Urine alkalinization therapy, Fluid and electrolyte maintenance therapy

Clinical Trials

Analgesic Effect of Oral 25% Glucose Versus Oral 24% Sucrose for Pain Relief During Heel Lance in Preterm Neonates

Not Applicable

Completed

Conditions: Pain

Interventions: Drug: Sucrose
Drug: Glucose

First Posted Date: 2013-08-29

Last Posted Date: 2016-06-27

Lead Sponsor: Lady Hardinge Medical College

Target Recruit Count: 94

Registration Number: NCT01931020

Locations: 🇮🇳
Lady Hardinge Medical College, New Delhi, Delhi1, India

Intracellular Counter-regulatory Mechanisms Following Low Blood Glucose

Not Applicable

Completed

Conditions: Diabetes Mellitus Type I
Hypoglycemia

Interventions: Other: Saline
Drug: Insulin (Insuman Rapid)
Drug: Glucose

First Posted Date: 2013-08-09

Last Posted Date: 2019-09-27

Lead Sponsor: University of Aarhus

Target Recruit Count: 9

Registration Number: NCT01919788

Locations: 🇩🇰
Institute of Clinical Medicine, Aarhus, Aarhus C, Denmark

Caudal Epidural Injection of Dextrose For Low Back Pain

Phase 2

Completed

Conditions: Back Pain Lower Back Chronic

Interventions: Drug: Saline
Drug: Dextrose

First Posted Date: 2012-03-07

Last Posted Date: 2018-04-30

Lead Sponsor: Smigel, Liza, M.D.

Target Recruit Count: 35

Registration Number: NCT01547364

Locations: 🇺🇸
Liza Smigel, M.D., Hilo, Hawaii, United States

Beta Cell Function in (Pre)Type 1 Diabetes

Not Applicable

Conditions: Type 1 Diabetes

Interventions: Drug: Glucose
Device: Continuous glucose monitoring

First Posted Date: 2011-07-26

Last Posted Date: 2013-12-30

Lead Sponsor: AZ-VUB

Target Recruit Count: 100

Registration Number: NCT01402037

Locations: 🇧🇪
UZ Antwerpen, Edegem, Belgium
🇧🇪
UZ Gent, Gent, Belgium
🇧🇪
UZ Brussels, Brussels, Belgium

Lactate to Treat Hypoglycemia

Phase 4

Withdrawn

Conditions: Hypoglycemia

Interventions: Drug: Lactate
Drug: Glucose

First Posted Date: 2011-07-04

Last Posted Date: 2020-07-31

Lead Sponsor: Institut d'Anesthesiologie des Alpes Maritimes

Registration Number: NCT01387477

Locations: 🇫🇷
Réanimation médico-chirurgicale, Nice, France

Efficacy of Clarithromycin Treatment in Prevention of Chronic Lung Disease in Premature Infants

Phase 4

Completed

Conditions: Chronic Lung Disease

Interventions: Drug: Clarithromycin
Drug: Dextrose

First Posted Date: 2011-03-31

Last Posted Date: 2011-03-31

Lead Sponsor: Zekai Tahir Burak Women's Health Research and Education Hospital

Target Recruit Count: 273

Registration Number: NCT01326611

Locations: 🇹🇷
Zekai Tahir Burak Maternity Teaching Hospital Neonatology department, Ankara, Turkey

Effect of LY2189265 on Insulin Secretion in Response to Intravenous Glucose

Phase 1

Completed

Conditions: Diabetes Mellitus, Type 2

Interventions: Biological: LY2189265
Drug: Placebo
Drug: Insulin
Drug: Glucose
Drug: Glucagon

First Posted Date: 2011-02-21

Last Posted Date: 2014-10-07

Lead Sponsor: Eli Lilly and Company

Target Recruit Count: 32

Registration Number: NCT01300260

Locations: 🇩🇪
For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician., Neuss, Germany