Glucose is a simple sugar (monosaccharide) generated during phosynthesis involving water, carbon and sunlight in plants. It is produced in humans via hepatic gluconeogenesis and breakdown of polymeric glucose forms (glycogenolysis). It circulates in human circulation as blood glucose and acts as an essential energy source for many organisms through aerobic or anaerobic respiration and fermentation. It is primarily stored as starch in plants and glycogen in animals to be used in various metabolic processes in the cellular level. Its aldohexose stereoisomer, dextrose or D-glucose, is the most commonly occurring isomer of glucose in nature. L-glucose is a synthesized enantiomer that is used as a low-calorie sweetener and laxative. The unspecified form of glucose is commonly supplied as an injection for nutritional supplementation or metabolic disorders where glucose levels are improperly regulated. Glucose is listed on the World Health Organization's List of Essential Medicines.
Glucose pharmaceutical formulations (oral tablets, injections) are indicated for caloric supply and carbohydrate supplementation in case of nutrient deprivation. It is also used in metabolic disorders such as hypoglycemia.
Kochi Medical School, Kohasu-Okocho, Nankoku, Japan
Butler Hospital, Providence, Rhode Island, United States
Environmental and Occupational Medicine, National Taiwan University Hospital, Taipei, Taiwan
Department of Clinical Pharmacology, Medical University of Vienna, Vienna, Austria
University Hospital of Rouen, Rouen, France
University Hospital and Medical Center, Stony Brook, New York, United States
University of Utah School of Medicine, Salt Lake City, Utah, United States
Baylor College of Medicine, Houston, Texas, United States
University of Virginia, Charlottesville, Virginia, United States
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