MedPath

Glucose

Generic Name
Glucose
Brand Names
Bss Ophthalmic Solution, Citrasate, Clinimix 2.75/5, Clinimix E 2.75/5, Dextroject, Dianeal, H.E.L.P.bicel, Hemosate Ultra, Lactate 1-2-3, Leukotrap, Naturalyte, Nauzene, Normosol-R, Nxstage Pureflow, Olimel, Periolimel, Physioneal 40, Sag-M, Sclerodex, Selectbag One
Drug Type
Small Molecule
Unique Ingredient Identifier
IY9XDZ35W2
Background

Glucose is a simple sugar (monosaccharide) generated during phosynthesis involving water, carbon and sunlight in plants. It is produced in humans via hepatic gluconeogenesis and breakdown of polymeric glucose forms (glycogenolysis). It circulates in human circulation as blood glucose and acts as an essential energy source for many organisms through aerobic or anaerobic respiration and fermentation. It is primarily stored as starch in plants and glycogen in animals to be used in various metabolic processes in the cellular level. Its aldohexose stereoisomer, dextrose or D-glucose, is the most commonly occurring isomer of glucose in nature. L-glucose is a synthesized enantiomer that is used as a low-calorie sweetener and laxative. The unspecified form of glucose is commonly supplied as an injection for nutritional supplementation or metabolic disorders where glucose levels are improperly regulated. Glucose is listed on the World Health Organization's List of Essential Medicines.

Indication

Glucose pharmaceutical formulations (oral tablets, injections) are indicated for caloric supply and carbohydrate supplementation in case of nutrient deprivation. It is also used in metabolic disorders such as hypoglycemia.

Associated Conditions
Arrhythmia, Caloric Deficit, Edema of the cerebrum, Hypoglycemia, Metabolic Alkalosis
Associated Therapies
Blood Specimen Collection, Electrolyte replacement, Nutritional supplementation, Parenteral Nutrition, Parenteral rehydration therapy, Plasmapheresis, Positive cardiac inotropic effect, Total parenteral nutrition therapy, Urine alkalinization therapy, Fluid and electrolyte maintenance therapy

Evolution of the Initial Distribution Volume of Glucose in the Severe Burned Adults

Phase 2
Recruiting
Conditions
Burns
Intensive Care
Emergencies
Interventions
Drug: Glucose 30% Intravenous Solution
First Posted Date
2024-06-24
Last Posted Date
2025-05-14
Lead Sponsor
Centre Hospitalier Régional Metz-Thionville
Target Recruit Count
15
Registration Number
NCT06469970
Locations
🇫🇷

CHR Metz-Thionville/Hopital de Mercy, Metz, France

Low-Dose IL-2 For The Reduction Of Vascular Inflammation In ACS -Clinical Outcomes & Follow-up Study

Recruiting
Conditions
Acute Coronary Syndromes
Interventions
Drug: Dextrose 5% in water
First Posted Date
2024-05-24
Last Posted Date
2024-06-10
Lead Sponsor
Cambridge University Hospitals NHS Foundation Trust
Target Recruit Count
60
Registration Number
NCT06427694
Locations
🇬🇧

Addenbrooke's Hospital, Cambridge, Cambridgeshire, United Kingdom

Intranasal Dexmedetomidine Versus Oral Midazolam Premedication for Postoperative Negative Behavior Changes in Children

Phase 4
Recruiting
Conditions
Behavior Problem
Interventions
Drug: normal Saline
Drug: Glucose solution
First Posted Date
2024-05-16
Last Posted Date
2024-08-16
Lead Sponsor
Fujian Provincial Hospital
Target Recruit Count
324
Registration Number
NCT06417125
Locations
🇨🇳

Fujian Provincial Hospital, Fuzhou, Fujian, China

Dextrose, Steroid, PRP: Choosing the Right Injection for CRS Relief; a RCT

Phase 4
Completed
Conditions
Carpal Tunnel Syndrome
Interventions
Drug: injection Dextrose water
Device: USG machine
First Posted Date
2024-04-05
Last Posted Date
2024-04-05
Lead Sponsor
Sheikh Zayed Medical College
Target Recruit Count
60
Registration Number
NCT06349824
Locations
🇵🇰

Sheikh Zayed Medical College, Rahim yar khan, Punjab, Pakistan

Comparison of Ultrasound-Guided Perimeniscal Steroid and 5% Dextrose Injections in Knee Osteoarthritis

Phase 4
Completed
Conditions
Meniscus; Degeneration
Gonarthrosis
Pain, Chronic
Interventions
Drug: Dextrose 5% in water
First Posted Date
2024-03-13
Last Posted Date
2024-03-13
Lead Sponsor
Kastamonu University
Target Recruit Count
31
Registration Number
NCT06308887
Locations
🇹🇷

Gamze Gül Güleç, Kastamonu, Turkey

Dextrose Prolotherapy on Articular Cartilage

Not Applicable
Recruiting
Conditions
Arthritis Knee
Interventions
Drug: Dextrose prolotherapy
First Posted Date
2024-03-08
Last Posted Date
2024-03-08
Lead Sponsor
Chang Gung Memorial Hospital
Target Recruit Count
60
Registration Number
NCT06301958
Locations
🇨🇳

Chang Gung Memorial Hospital, Chiayi, Chiayi City, 嘉義市, Taiwan

Pleurodesis Using Hypertonic Glucose

Phase 2
Not yet recruiting
Conditions
Air Leak From Lung
Interventions
Drug: Dextrose 50
Other: Standard of Care - No Dextrose 50
First Posted Date
2024-03-05
Last Posted Date
2024-03-05
Lead Sponsor
Lawson Health Research Institute
Target Recruit Count
40
Registration Number
NCT06293885
Locations
🇨🇦

London Health Sciences Centre, London, Ontario, Canada

Hypertonic Dextrose Injection and Physical Therapy for Frozen Shoulder

Not Applicable
Not yet recruiting
Conditions
Frozen Shoulder
Interventions
Drug: 15% hypertonic dextrose
Drug: Normal saline
Other: physical therapy
First Posted Date
2023-12-12
Last Posted Date
2023-12-12
Lead Sponsor
Tri-Service General Hospital
Target Recruit Count
60
Registration Number
NCT06165926

Nonpharmacological Pain Management in Neonates

Not Applicable
Not yet recruiting
Conditions
Pain Management
Neonates Pain Management
Interventions
Behavioral: no intervention
Drug: nonnutritive suckling
Drug: oral glucose 25%
Behavioral: facilitated tuckling
First Posted Date
2023-12-04
Last Posted Date
2023-12-04
Lead Sponsor
Assiut University
Target Recruit Count
164
Registration Number
NCT06155825

Nafamostat Mesilate in the Treatment of Severe Infection-associated Coagulopathy

Phase 4
Not yet recruiting
Conditions
Sepsis-induced Coagulopathy
Nafamostat Mesilate
Sepsis
Interventions
First Posted Date
2023-10-12
Last Posted Date
2023-10-12
Lead Sponsor
Xu Li
Target Recruit Count
778
Registration Number
NCT06078839
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