Glucose

Generic Name: Glucose

Brand Names: Bss Ophthalmic Solution, Citrasate, Clinimix 2.75/5, Clinimix E 2.75/5, Dextroject, Dianeal, H.E.L.P.bicel, Hemosate Ultra, Lactate 1-2-3, Leukotrap, Naturalyte, Nauzene, Normosol-R, Nxstage Pureflow, Olimel, Periolimel, Physioneal 40, Sag-M, Sclerodex, Selectbag One

Drug Type: Small Molecule

Unique Ingredient Identifier: IY9XDZ35W2

Background: Glucose is a simple sugar (monosaccharide) generated during phosynthesis involving water, carbon and sunlight in plants. It is produced in humans via hepatic gluconeogenesis and breakdown of polymeric glucose forms (glycogenolysis). It circulates in human circulation as blood glucose and acts as an essential energy source for many organisms through aerobic or anaerobic respiration and fermentation. It is primarily stored as starch in plants and glycogen in animals to be used in various metabolic processes in the cellular level. Its aldohexose stereoisomer, dextrose or D-glucose, is the most commonly occurring isomer of glucose in nature. L-glucose is a synthesized enantiomer that is used as a low-calorie sweetener and laxative. The unspecified form of glucose is commonly supplied as an injection for nutritional supplementation or metabolic disorders where glucose levels are improperly regulated. Glucose is listed on the World Health Organization's List of Essential Medicines.

Indication: Glucose pharmaceutical formulations (oral tablets, injections) are indicated for caloric supply and carbohydrate supplementation in case of nutrient deprivation. It is also used in metabolic disorders such as hypoglycemia.

Associated Conditions: Arrhythmia, Caloric Deficit, Edema of the cerebrum, Hypoglycemia, Metabolic Alkalosis

Associated Therapies: Blood Specimen Collection, Electrolyte replacement, Nutritional supplementation, Parenteral Nutrition, Parenteral rehydration therapy, Plasmapheresis, Positive cardiac inotropic effect, Total parenteral nutrition therapy, Urine alkalinization therapy, Fluid and electrolyte maintenance therapy

Clinical Trials

Ketone Ester Intervention in Alcohol Use Disorder

Phase 2

Recruiting

Conditions: Alcohol Use Disorder
Alcohol Drinking

Interventions: Drug: Isocaloric dextrose placebo
Dietary Supplement: Ketone Ester "(R)-3-hydroxybutyl (R)-3-hydroxybutyrate"
Other: Alcohol drinks

First Posted Date: 2020-11-05

Last Posted Date: 2024-10-29

Lead Sponsor: University of Pennsylvania

Target Recruit Count: 20

Registration Number: NCT04616781

Locations: 🇺🇸
University of Pennsylvania Center for Studies of Addiction, Philadelphia, Pennsylvania, United States

Corticosteroid and Repeated Dextrose Hydro-dissection for Carpal Tunnel Syndrome Patients

Not Applicable

Conditions: Carpal Tunnel Syndrome

Interventions: Drug: Dextrose 5% in water
Drug: Triamcinolone Acetonide

First Posted Date: 2020-10-08

Last Posted Date: 2021-12-15

Lead Sponsor: National Taiwan University Hospital

Target Recruit Count: 60

Registration Number: NCT04579783

Locations: 🇨🇳
National Taiwan University Hospital, Bei-Hu Branch, Taipei, Wanhua District, Taiwan

Role of Liquid Phase Concentrated Growth Factors vs. Hypertonic Dextrose Prolotherapy for Management of Patients With Disc Displacement Without Reduction

Phase 2

Completed

Conditions: Temporomandibular Joint Disorders
Temporomandibular Disorder

Interventions: Biological: Liquid Phase Concentrated Growth Factor (LPCGFs)
Drug: Hypertonic Dextrose Solution

First Posted Date: 2020-09-22

Last Posted Date: 2023-12-04

Lead Sponsor: Nourhan M.Aly

Target Recruit Count: 24

Registration Number: NCT04557878

Locations: 🇪🇬
Faculty of Dentistry, Alexandria University, Alexandria, Egypt

Effect of Glucose 5% on Labor Length

Not Applicable

Conditions: Induction of Labor Affected Fetus / Newborn

Interventions: Drug: Dextrose 5%/Nacl 0.3% Inj_#3
Drug: Saline

First Posted Date: 2020-07-30

Last Posted Date: 2020-07-30

Lead Sponsor: Suez Canal University

Target Recruit Count: 476

Registration Number: NCT04492150

Locations: 🇪🇬
Suez canal University, Ismailia, Egypt

Randomized Evaluation of Shenfu Injection to Reduce Myocardial Injury

Phase 4

Conditions: Myocardial Infarction

Interventions: Drug: 5% Glucose Injection
Drug: Shenfu Injection

First Posted Date: 2020-07-30

Last Posted Date: 2021-09-10

Lead Sponsor: Beijing Anzhen Hospital

Target Recruit Count: 326

Registration Number: NCT04493840

Locations: 🇨🇳
Beijing Anzhen Hospital, Capital Medical University, Beijing, China

The Use of Sedation Drugs in the Procedure of Administering Surfactant Without Intubation (LISA/MIST)

Phase 1

Conditions: Gestational Age Conditions
Neonatal Respiratory Distress Syndrome

Interventions: Drug: Ketamine
Drug: Glucose

First Posted Date: 2020-06-01

Last Posted Date: 2022-01-19

Lead Sponsor: Medical University of Warsaw

Target Recruit Count: 60

Registration Number: NCT04409665

Locations: 🇵🇱
Uniwersyteckie Centrum Zdrowia Kobiety Noworodka, Warsaw, Mazowieckie, Poland

Age-Related Effects of THC

Early Phase 1

Completed

Conditions: Tolerance
Adolescent Behavior
THC

Interventions: Drug: Dextrose
Drug: Dronabinol

First Posted Date: 2020-03-04

Last Posted Date: 2023-11-09

Lead Sponsor: University of Chicago

Target Recruit Count: 24

Registration Number: NCT04294966

Locations: 🇺🇸
University of Chicago Hospital, Chicago, Illinois, United States
🇺🇸
University of Chicago, Chicago, Illinois, United States

Acetaminophen and Ascorbate in Sepsis: Targeted Therapy to Enhance Recovery

Phase 2

Completed

Conditions: Critical Illness
Acute Respiratory Distress Syndrome
Respiratory Failure
Sepsis

Interventions: Drug: 5% Dextrose (room temperature)
Drug: 5% Dextrose refrigerated
Drug: Intravenous Acetaminophen (room temperature)
Drug: Intravenous Vitamin C (refrigerated)

First Posted Date: 2020-03-02

Last Posted Date: 2023-10-17

Lead Sponsor: Massachusetts General Hospital

Target Recruit Count: 488

Registration Number: NCT04291508

Locations: 🇺🇸
Massachusetts General Hospital, Boston, Massachusetts, United States
🇺🇸
University of Texas Health Science Center, Houston, Texas, United States
🇺🇸
Hennepin County Medical Center, Minneapolis, Minnesota, United States

and more 38 locations

Platelet-rich Plasma Injection for Ulnar Neuropathy at Elbow

Not Applicable

Completed

Conditions: Ulnar Neuropathy at Elbow

Interventions: Drug: platelet-rich plasma
Drug: 5% dextrose

First Posted Date: 2020-02-11

Last Posted Date: 2024-04-10

Lead Sponsor: Yung-Tsan Wu

Target Recruit Count: 30

Registration Number: NCT04264000

Locations: 🇨🇳
Yung-Tsan Wu, Taipei, Neihu District, Taiwan

Oral Dextrose Formula in Performance of Soccer Athlete

Not Applicable

Completed

Conditions: Athletes

Interventions: Drug: 10% Dextrose
Drug: Natrium Dextrose

First Posted Date: 2019-12-20

Last Posted Date: 2019-12-20

Lead Sponsor: Hasanuddin University

Target Recruit Count: 30

Registration Number: NCT04206579

Locations: 🇮🇩
Makassar State University, Makasar, South Sulawesi, Indonesia

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