Glucose

Generic Name: Glucose

Brand Names: Bss Ophthalmic Solution, Citrasate, Clinimix 2.75/5, Clinimix E 2.75/5, Dextroject, Dianeal, H.E.L.P.bicel, Hemosate Ultra, Lactate 1-2-3, Leukotrap, Naturalyte, Nauzene, Normosol-R, Nxstage Pureflow, Olimel, Periolimel, Physioneal 40, Sag-M, Sclerodex, Selectbag One

Drug Type: Small Molecule

Unique Ingredient Identifier: IY9XDZ35W2

Background: Glucose is a simple sugar (monosaccharide) generated during phosynthesis involving water, carbon and sunlight in plants. It is produced in humans via hepatic gluconeogenesis and breakdown of polymeric glucose forms (glycogenolysis). It circulates in human circulation as blood glucose and acts as an essential energy source for many organisms through aerobic or anaerobic respiration and fermentation. It is primarily stored as starch in plants and glycogen in animals to be used in various metabolic processes in the cellular level. Its aldohexose stereoisomer, dextrose or D-glucose, is the most commonly occurring isomer of glucose in nature. L-glucose is a synthesized enantiomer that is used as a low-calorie sweetener and laxative. The unspecified form of glucose is commonly supplied as an injection for nutritional supplementation or metabolic disorders where glucose levels are improperly regulated. Glucose is listed on the World Health Organization's List of Essential Medicines.

Indication: Glucose pharmaceutical formulations (oral tablets, injections) are indicated for caloric supply and carbohydrate supplementation in case of nutrient deprivation. It is also used in metabolic disorders such as hypoglycemia.

Associated Conditions: Arrhythmia, Caloric Deficit, Edema of the cerebrum, Hypoglycemia, Metabolic Alkalosis

Associated Therapies: Blood Specimen Collection, Electrolyte replacement, Nutritional supplementation, Parenteral Nutrition, Parenteral rehydration therapy, Plasmapheresis, Positive cardiac inotropic effect, Total parenteral nutrition therapy, Urine alkalinization therapy, Fluid and electrolyte maintenance therapy

Clinical Trials

Pre-emptive Analgesia Effect in Different Psycho-emotional Status Patients During Lower Third Molar Surgical Extractions

Not Applicable

Completed

Conditions: Pre-emptive Analgesia in Different Psycho-emotional Status Patients

Interventions: Other: No drug
Drug: Ibuprofen 400 mg and Acetaminophen 500 mg
Drug: Glucose

First Posted Date: 2019-12-17

Last Posted Date: 2019-12-17

Lead Sponsor: Lithuanian University of Health Sciences

Target Recruit Count: 45

Registration Number: NCT04202224

Locations: 🇱🇹
Lithuanian university of health sciences, Kaunas, Lithuania

High Protein Formula on Enteral Feeding in Clinical Improvement and Malnutrition at Intensive Care Unit Patients

Not Applicable

Completed

Conditions: Critically Ill
Intensive Care Unit

Interventions: Other: High Protein Polymeric Formula
Other: Oligomeric Formula
Drug: 5% Dextrose

First Posted Date: 2019-11-05

Last Posted Date: 2019-11-05

Lead Sponsor: Hasanuddin University

Target Recruit Count: 60

Registration Number: NCT04150978

Locations: 🇮🇩
Wahidin Sudirohusodo General Hospital, Makassar, South Sulawesi, Indonesia

Effect of GLP-1 on Microvascular Insulin Responses in Type 1 Diabetes

Early Phase 1

Withdrawn

Conditions: Type 1 Diabetes
Insulin Sensitivity/Resistance

Interventions: Drug: GLP-1
Drug: Insulin
Drug: Dextrose 20 % in Water

First Posted Date: 2019-10-21

Last Posted Date: 2022-03-22

Lead Sponsor: University of Virginia

Registration Number: NCT04133922

Locations: 🇺🇸
University of Virginia, Charlottesville, Virginia, United States

Dynamic Connectivity Under Metabolic Constraints

Phase 4

Conditions: Diet Modification
Aging
Insulin Resistance
Healthy

Interventions: Drug: Ketones
Drug: Glucose

First Posted Date: 2019-09-27

Last Posted Date: 2019-09-27

Lead Sponsor: Stony Brook University

Target Recruit Count: 80

Registration Number: NCT04106882

Locations: 🇺🇸
Bioengineering Building , Stony Brook University, Stony Brook, New York, United States
🇺🇸
Martinos Center for Biomedical Research, Building 149, Charlestown, Massachusetts, United States