Clonazepam
- Generic Name
- Clonazepam
- Brand Names
- Clonapam, Klonopin, Rivotril
- Drug Type
- Small Molecule
- Chemical Formula
- C15H10ClN3O3
- CAS Number
- 1622-61-3
- Unique Ingredient Identifier
- 5PE9FDE8GB
- Background
A benzodiazepine used to treat various seizures, including myotonic or atonic seizures, photosensitive epilepsy, and absence seizures, although tolerance may develop. The agent has also been indicated for treating panic disorder. The mechanism of action appears to involve the enhancement of gamma-aminobutyric acid receptor responses.
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- Indication
Clonazepam is indicated as monotherapy or as an adjunct in the treatment of Lennox-Gastaut syndrome (petit mal variant), akinetic, and myoclonic seizures. Furthermore, clonazepam may also be of some value in patients with absence spells (petit mal) who have failed to respond to succinimides. Additionally, clonazepam is also indicated for the treatment of pan...
- Associated Conditions
- Akinetic seizures, Burning Mouth Syndrome, Essential Tremor, Gilles de la Tourette's Syndrome, Lennox-Gastaut Syndrome, Mixed manic depressive episode, Panic Disorder, Rapid Eye Movement Sleep Disorder, Restless Legs Syndrome (RLS), Tardive Dyskinesia (TD), Acute Manic episode, Myoclonic seizures, Refractory absence Seizures
- Associated Therapies
- -
Improving Treatment Outcomes in Pharmacotherapy of Generalized Social Anxiety Disorder
- Conditions
- Interventions
- First Posted Date
- 2006-01-27
- Last Posted Date
- 2013-10-14
- Lead Sponsor
- Massachusetts General Hospital
- Target Recruit Count
- 397
- Registration Number
- NCT00282828
- Locations
- 🇺🇸
University of California San Diego, La Jolla, California, United States
🇨🇦McMaster University Medical Centre Anxiety Disorders Clinic, Hamilton, Ontario, Canada
🇺🇸Center for Anxiety and Traumatic Stress Disorders, Boston, Massachusetts, United States
Therapies for Treatment-Resistant Panic Disorder Symptoms
- Conditions
- Interventions
- First Posted Date
- 2005-07-11
- Last Posted Date
- 2014-06-11
- Lead Sponsor
- Massachusetts General Hospital
- Target Recruit Count
- 46
- Registration Number
- NCT00118417
- Locations
- 🇺🇸
Massachusetts General Hospital, Boston, Massachusetts, United States
Drug Development Updates
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