Somatostatin

Generic Name
Somatostatin
Brand Names
-
Drug Type
Small Molecule
Chemical Formula
C76H104N18O19S2
CAS Number
38916-34-6
Unique Ingredient Identifier
6E20216Q0L
Background

Somatostatin, also known as growth hormone-inhibiting hormone, is a naturally-occurring peptide hormone of 14 or 28 amino acid residues that regulates the endocrine system. It is secreted by the D cells of the islets to inhibit the release of insulin and glucagon, and is also generated in the hypothalamus, where it inhibits the release of growth hormone and...

Indication

For the symptomatic treatment of acute bleeding from esophageal varices. Other treatment options for long-term management of the condition may be considered if necessary, once initial control has been established.

Associated Conditions
Acromegaly, Bleeding caused by Gastritis erosive, Diabetic Ketoacidosis, Duodenal ulcer haemorrhage, Fistula of small intestine, Fistula, Biliary, Gastric ulcer haemorrhage, Gastritis haemorrhagic, Oesophageal varices haemorrhage, Pancreatic Fistula, Postoperative Complications caused by Pancreatic Surgery
Associated Therapies
Restriction of Secretions

A Trial of Somatostatin With Endoscopic Variceal Ligation (EVL) in Control of Acute Variceal Bleeding

First Posted Date
2010-12-28
Last Posted Date
2010-12-28
Lead Sponsor
Govind Ballabh Pant Hospital
Target Recruit Count
61
Registration Number
NCT01267669
Locations
🇮🇳

Department of Gastroenterology, G B Pant Hospital, New Delhi, Delhi, India

Identifying the Effect of Somatostatin Treatment in Early Postoperative Simple Small Bowel Obstruction

First Posted Date
2010-03-08
Last Posted Date
2011-08-03
Lead Sponsor
Nanjing PLA General Hospital
Target Recruit Count
44
Registration Number
NCT01082627
Locations
🇨🇳

Nanjing PLAGH, Nanjing, Jiangsu, China

Peripheral Metabolic Effects of Somatostatin

Not Applicable
Completed
Conditions
Interventions
First Posted Date
2010-02-04
Last Posted Date
2013-01-21
Lead Sponsor
University of Aarhus
Target Recruit Count
8
Registration Number
NCT01062529
Locations
🇩🇰

Medical department M, Aarhus, Denmark

Efficacy of Administration of Somatostatin in the Prevention of Post-endoscopic Retrograde Cholangiopancreatography (ERCP) Pancreatitis

First Posted Date
2010-02-02
Last Posted Date
2011-06-22
Lead Sponsor
Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Target Recruit Count
510
Registration Number
NCT01060826
Locations
🇪🇸

Hospital de la Santa Creu i Sant Pau, Barcelona, Spain

🇪🇸

Endoscopy Unit Hospital de la Santa Creu i Sant Pau, Barcelona, Spain

New Chemotherapy Regimen in the Treatment of Advanced Gallbladder Carcinoma

First Posted Date
2010-01-21
Last Posted Date
2013-12-20
Lead Sponsor
Shanghai Jiao Tong University School of Medicine
Target Recruit Count
216
Registration Number
NCT01053390
Locations
🇨🇳

Xinhua hospital affiliated shanghai jiaotong, Shanghai, China

Comparison of Terlipressin, Somatostatin, and Octreotide for Control of Variceal Bleeding

First Posted Date
2009-08-26
Last Posted Date
2018-03-19
Lead Sponsor
Korea University
Target Recruit Count
1034
Registration Number
NCT00966355
Locations
🇰🇷

Korea University Anam Hospital, Seoul, Korea, Republic of

Measurement of Glucose Metabolism in Humans Using Magnetic Resonance at 4 Tesla. Substudy: Hypoglycemia Unawareness

First Posted Date
2008-11-19
Last Posted Date
2018-01-18
Lead Sponsor
University of Minnesota
Target Recruit Count
19
Registration Number
NCT00793741
Locations
🇺🇸

University of Minnesota, Minneapolis, Minnesota, United States

Measurement of Glucose/Glycogen Metabolism in Humans Using Magnetic Resonance at 4 or 7 Tesla

Phase 2
Completed
Conditions
Interventions
First Posted Date
2008-11-06
Last Posted Date
2019-12-18
Lead Sponsor
University of Minnesota
Target Recruit Count
10
Registration Number
NCT00786825
Locations
🇺🇸

University of Minnesota, Minneapolis, Minnesota, United States

Effect of Elevated Plasma-Free-Fatty-Acids on Renal Hemodynamic Parameters

First Posted Date
2007-02-06
Last Posted Date
2007-02-06
Lead Sponsor
Medical University of Vienna
Target Recruit Count
9
Registration Number
NCT00431665
Locations
🇦🇹

Department of Clinical Pharmacology, Medical University of Vienna, Vienna, Austria

© Copyright 2024. All Rights Reserved by MedPath