Somatostatin

Generic Name
Somatostatin
Brand Names
-
Drug Type
Small Molecule
Chemical Formula
C76H104N18O19S2
CAS Number
38916-34-6
Unique Ingredient Identifier
6E20216Q0L
Background

Somatostatin, also known as growth hormone-inhibiting hormone, is a naturally-occurring peptide hormone of 14 or 28 amino acid residues that regulates the endocrine system. It is secreted by the D cells of the islets to inhibit the release of insulin and glucagon, and is also generated in the hypothalamus, where it inhibits the release of growth hormone and...

Indication

For the symptomatic treatment of acute bleeding from esophageal varices. Other treatment options for long-term management of the condition may be considered if necessary, once initial control has been established.

Associated Conditions
Acromegaly, Bleeding caused by Gastritis erosive, Diabetic Ketoacidosis, Duodenal ulcer haemorrhage, Fistula of small intestine, Fistula, Biliary, Gastric ulcer haemorrhage, Gastritis haemorrhagic, Oesophageal varices haemorrhage, Pancreatic Fistula, Postoperative Complications caused by Pancreatic Surgery
Associated Therapies
Restriction of Secretions

The Effect of Somatostatin for Treatment of Post Hepatectomy Liver Failure (PHLF)

Phase 3
Conditions
Interventions
First Posted Date
2016-08-29
Last Posted Date
2016-09-12
Lead Sponsor
Korea University Anam Hospital
Target Recruit Count
20
Registration Number
NCT02882347
Locations
🇰🇷

Korea university Anam hospital, Seoul, Korea, Republic of

Metabolic Consequences of Gastrointestinal Surgery

First Posted Date
2016-07-19
Last Posted Date
2019-04-02
Lead Sponsor
Cambridge University Hospitals NHS Foundation Trust
Target Recruit Count
81
Registration Number
NCT02836353
Locations
🇬🇧

Cambridge University Hospitals NHS Foundation Trust, Cambridge, Cambridgeshire, United Kingdom

Vasoactive Drugs in Real World Practice

First Posted Date
2016-05-02
Last Posted Date
2016-05-03
Lead Sponsor
Kaohsiung Veterans General Hospital.
Target Recruit Count
150
Registration Number
NCT02757703
Locations
🇨🇳

Division of Gastroenterology, Department of Internal Medicine, Kaohsiung, Taiwan

In Vivo Assessment of Cellular Metabolism in Humans

Phase 1
Completed
Conditions
Interventions
First Posted Date
2016-04-22
Last Posted Date
2022-08-03
Lead Sponsor
K. Sreekumaran Nair
Target Recruit Count
17
Registration Number
NCT02748369
Locations
🇺🇸

Mayo Clinic in Rochester, Rochester, Minnesota, United States

Treatment With Sandostatin in Patients With Castrate Resistance Prostate Cancer Showing Uptake of 68Ga-DOTATET

Phase 1
Conditions
Interventions
First Posted Date
2015-12-16
Last Posted Date
2015-12-16
Lead Sponsor
Hadassah Medical Organization
Target Recruit Count
30
Registration Number
NCT02631616

Impact of Endogenous E2 on SSI and GH Rebound

First Posted Date
2014-01-03
Last Posted Date
2016-03-16
Lead Sponsor
Mayo Clinic
Target Recruit Count
62
Registration Number
NCT02026973
Locations
🇺🇸

Mayo Clinic in Rochester, Rochester, Minnesota, United States

Multi-center Clinical Study of Early Antibios of Severe Acute Pancreatitis

First Posted Date
2013-11-25
Last Posted Date
2013-11-25
Lead Sponsor
Erzhen Chen
Target Recruit Count
60
Registration Number
NCT01992198
Locations
🇨🇳

Depatrment of EICU,Ruijin Hospital, Shanghai, Shanghai, China

Application of Somatostatin for Advanced Gastric Cancer After D2 Lymph Node Dissection

First Posted Date
2013-08-02
Last Posted Date
2013-08-02
Lead Sponsor
First Affiliated Hospital, Sun Yat-Sen University
Target Recruit Count
2
Registration Number
NCT01914692

Effects of Canagliflozin on C-peptide Clearance in Healthy Volunteers

First Posted Date
2012-08-15
Last Posted Date
2013-06-07
Lead Sponsor
Janssen-Cilag International NV
Target Recruit Count
10
Registration Number
NCT01665638

Effects of Somatostatin on Post-endoscopic Portal Hemodynamic in Cirrhotic Patients With Esophageal Gastric Varices

First Posted Date
2011-08-31
Last Posted Date
2011-09-02
Lead Sponsor
Yunsheng Yang
Target Recruit Count
126
Registration Number
NCT01426087
Locations
🇨🇳

Site, Beijing, China

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