Nalbuphine

Generic Name
Nalbuphine
Brand Names
-
Drug Type
Small Molecule
Chemical Formula
C21H27NO4
CAS Number
20594-83-6
Unique Ingredient Identifier
L2T84IQI2K
Background

A narcotic used as a pain medication. It appears to be an agonist at kappa opioid receptors and an antagonist or partial agonist at mu opioid receptors. Nalbuphine is the only opioid analgesic that is not a controlled substance in the United States.

Indication

For the relief of moderate to severe pain.

Associated Conditions
Severe Pain, Moderate Pain, Obstetrical analgesia therapy
Associated Therapies
Perioperative analgesia, Obstetric analgesia
Clinical Trials
Related News

Effect of Caudal Nalbuphine on Postoperative Emergence Agitation in Pediatrics Undergoing Infra-umbilical Surgeries

First Posted Date
2022-02-18
Last Posted Date
2022-02-18
Lead Sponsor
Assiut University
Target Recruit Count
80
Registration Number
NCT05245721

Nalbuphine Versus Morphine for Perioperative Tumor Ablation

First Posted Date
2021-10-11
Last Posted Date
2022-12-29
Lead Sponsor
Zhongda Hospital
Target Recruit Count
316
Registration Number
NCT05073744
Locations
🇨🇳

The Second Hospital of Anhui Medical University, Hefei, Anhui, China

🇨🇳

The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China

🇨🇳

Anhui Province Cancer Hospital, Hefei, Anhui, China

and more 17 locations

Epidural Nalbuphine Versus Dexmedetomidine as Adjuvants to Bupivacaine in Lower Limb Surgeries

First Posted Date
2021-09-13
Last Posted Date
2023-05-12
Lead Sponsor
Zagazig University
Target Recruit Count
23
Registration Number
NCT05041270
Locations
🇪🇬

faculty of medicine, Zagazig university, Zagazig, Elsharqya, Egypt

Intrathecal Midazolam, Fentanyl and Nalbuphine as Adjuvants to Bupivacaine in Spinal Anesthesia for Cesarean Section

First Posted Date
2021-06-18
Last Posted Date
2022-04-05
Lead Sponsor
Benha University
Target Recruit Count
100
Registration Number
NCT04932083
Locations
🇪🇬

Samar Rafik Amin, Banhā, Qalubia, Egypt

A Single Bolus of Dexmedetomidine Versus Nalbuphine in Postoperative Agitation

First Posted Date
2021-06-16
Last Posted Date
2024-05-17
Lead Sponsor
Assiut University
Target Recruit Count
90
Registration Number
NCT04928391
Locations
🇪🇬

Omar Soliman, Assiut, Assuit, Egypt

🇪🇬

Assiut university hospital, Assiut, Egypt

The Effect of Analgesic Drugs on Respiratory Center

First Posted Date
2020-05-04
Last Posted Date
2020-05-04
Lead Sponsor
Chun Pan
Target Recruit Count
50
Registration Number
NCT04372342
Locations
🇨🇳

Zhongda Hospital, Southeast University, Nanjing, Jiangsu, China

Dexmedetomidine Versus Nalbuphine in Prevention of Emergence Agitation Following Adenotonsillectomy in Pediatrics

First Posted Date
2019-08-16
Last Posted Date
2019-08-20
Lead Sponsor
Ain Shams University
Target Recruit Count
120
Registration Number
NCT04058899
Locations
🇪🇬

Ain Shams University, Cairo, Egypt

Conscious Sedation for Cataract Operations Under Topical Anaesthesia

First Posted Date
2019-05-01
Last Posted Date
2021-01-08
Lead Sponsor
Menoufia University
Target Recruit Count
100
Registration Number
NCT03933280
Locations
🇪🇬

Faculty of Medicine, Cairo, Shebin El-kom, Egypt

Intrathecal Nalbuphine Versus Midazolam in Cesarean Section

First Posted Date
2019-04-17
Last Posted Date
2019-12-24
Lead Sponsor
Zagazig University
Target Recruit Count
90
Registration Number
NCT03918187
Locations
🇪🇬

Olfat Abd Elmoniem Ibrahem Amin, Zagazig, Eygpt/zagazig, Egypt

Pharmacokinetics of Nalbuphine Injection

Phase 4
Completed
Conditions
Pain, Postoperative
Interventions
Drug: Nalbuphine
First Posted Date
2019-02-01
Last Posted Date
2019-02-01
Lead Sponsor
Yung Shin Pharm. Ind. Co., Ltd.
Target Recruit Count
14
Registration Number
NCT03826316
Locations
🇨🇳

Taichung Veterans General Hospital, Taichung, Taiwan

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