Nalbuphine

Generic Name
Nalbuphine
Brand Names
-
Drug Type
Small Molecule
Chemical Formula
C21H27NO4
CAS Number
20594-83-6
Unique Ingredient Identifier
L2T84IQI2K
Background

A narcotic used as a pain medication. It appears to be an agonist at kappa opioid receptors and an antagonist or partial agonist at mu opioid receptors. Nalbuphine is the only opioid analgesic that is not a controlled substance in the United States.

Indication

For the relief of moderate to severe pain.

Associated Conditions
Severe Pain, Moderate Pain, Obstetrical analgesia therapy
Associated Therapies
Perioperative analgesia, Obstetric analgesia
Clinical Trials
Related News

Nalbuphine Versus Morphine for Mucositis Pain in Pediatric Cancer Patients

First Posted Date
2019-01-31
Last Posted Date
2021-08-02
Lead Sponsor
Children's Cancer Hospital Egypt 57357
Target Recruit Count
80
Registration Number
NCT03825887
Locations
🇪🇬

CCHE, Cairo, Egypt

Erector Spinae Plane Block Versus Opioid Based General Anesthesia During Laparoscopic Bariatric Surgery

First Posted Date
2019-01-10
Last Posted Date
2020-01-14
Lead Sponsor
Cairo University
Target Recruit Count
28
Registration Number
NCT03798522
Locations
🇪🇬

Hany Mohammed El-Hadi Shoukat Mohammed, Giza, Egypt

The 90% Effective Dose of Nalbuphine in Mechanical Ventilated Patients in the ICU

Phase 4
Conditions
Pain
Interventions
Drug: Nalbuphine
First Posted Date
2018-12-26
Last Posted Date
2018-12-26
Lead Sponsor
Hua-Qing Shu
Target Recruit Count
60
Registration Number
NCT03786887
Locations
🇨🇳

Department of Critical Care Medicine, Union Hospital, Wuhan, Wuhan, China

Postoperative Pain and Discomfort After Orbital Decompression

First Posted Date
2018-06-19
Last Posted Date
2018-12-26
Lead Sponsor
Sun Yat-sen University
Target Recruit Count
63
Registration Number
NCT03562611
Locations
🇨🇳

Sun Yat-sen University, Guangzhou, Guangdong, China

Nalbuphine Plus Caudal Bupivacaine in Hypospadius Repair

Not Applicable
Completed
Conditions
Post Operative Pain
Interventions
Drug: Nalbuphine
First Posted Date
2018-03-26
Last Posted Date
2021-03-24
Lead Sponsor
Assiut University
Target Recruit Count
60
Registration Number
NCT03476772
Locations
🇪🇬

Faculty of Medicine, Assiut, Egypt

Nalbuphine as an Adjuvant to Local Anaesthetic Mixture in Peribulbar Cataract Surgery

First Posted Date
2018-02-19
Last Posted Date
2018-05-30
Lead Sponsor
Cairo University
Target Recruit Count
40
Registration Number
NCT03436836
Locations
🇪🇬

Ahmed Abdalla Mohamed, Cairo, Egypt

🇪🇬

Ahmed Abdalla, Cairo, Egypt

Nalbuphine and Flurbiprofen for Oculoplastic Surgery

First Posted Date
2018-02-06
Last Posted Date
2021-02-01
Lead Sponsor
Sun Yat-sen University
Target Recruit Count
330
Registration Number
NCT03422887
Locations
🇨🇳

Sun Yat-sen University, Guangzhou, Guangdong, China

Intraperitoneal Bupivacaine With Magnesium or Nalbuphine for Postoperative Pain Control in Laparoscopic Hysterectomy

First Posted Date
2018-01-08
Last Posted Date
2019-07-16
Lead Sponsor
Ain Shams University
Target Recruit Count
80
Registration Number
NCT03393572
Locations
🇪🇬

Marwa Elbeialy, Cairo, Egypt

Analgesia Comparison of Nalbuphine and Morphine for Laparoscopic Myomectomy

First Posted Date
2017-09-20
Last Posted Date
2017-11-06
Lead Sponsor
Peking University First Hospital
Target Recruit Count
80
Registration Number
NCT03288428
Locations
🇨🇳

First hospital Peking University, Beijing, Beijing, China

Pharmacokinetics of Nalbuphine After Intravenous and Intranasal Administration in Infants

Phase 1
Terminated
Conditions
Pharmacokinetic
Interventions
Drug: Nalbuphine
First Posted Date
2017-02-23
Last Posted Date
2021-12-14
Lead Sponsor
University Children's Hospital, Zurich
Target Recruit Count
51
Registration Number
NCT03059511
Locations
🇨🇭

Childens Hospital Zurich, Zurich, Switzerland

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