Lithium carbonate
- Generic Name
- Lithium carbonate
- Brand Names
- Carbolith, Lithane, Lithmax, Lithobid
- Drug Type
- Small Molecule
- Chemical Formula
- CLi2O3
- CAS Number
- 554-13-2
- Unique Ingredient Identifier
- 2BMD2GNA4V
- Background
Lithium has been used to treat manic episodes since the 19th century. Though it is widely used, its mechanism of action is still unknown. Lithium carbonate has a narrow therapeutic range and so careful monitoring is required to avoid adverse effects.
- Indication
Lithium carbonate is indicated as a monotherapy for the treatment of acute manic and mixed episodes associated with bipolar 1 disorder in patients ≥7 years of age. It is also indicated as a maintenance treatment for bipolar 1 disorder in patients ≥7 years of age.
- Associated Conditions
- Bipolar 1 Disorder, Mixed manic depressive episode, Acute Manic episode
- Associated Therapies
- -
Safety and Pharmacokinetics Study of Oral Lithium in Patients With Chronic Spinal Cord Injury
- Conditions
- First Posted Date
- 2007-02-05
- Last Posted Date
- 2012-01-16
- Lead Sponsor
- The University of Hong Kong
- Target Recruit Count
- 20
- Registration Number
- NCT00431171
- Locations
- 🇨🇳
MacLehose Medical Rehabilitation Centre, Pokfulam, Hong Kong SAR, China
Lithium Carbonate in Treating Patients With Acute Intestinal Graft-Versus-Host-Disease (GVHD) After Donor Stem Cell Transplant
- Conditions
- Noncontiguous Stage II Mantle Cell LymphomaNoncontiguous Stage II Marginal Zone LymphomaNoncontiguous Stage II Small Lymphocytic LymphomaPreviously Treated Childhood RhabdomyosarcomaPrimary MyelofibrosisRecurrent Adult Acute Myeloid LeukemiaRecurrent Adult Burkitt LymphomaRecurrent Adult Diffuse Mixed Cell LymphomaRecurrent Adult Hodgkin LymphomaRecurrent Adult Immunoblastic Large Cell Lymphoma
- Interventions
- First Posted Date
- 2006-12-07
- Last Posted Date
- 2017-03-07
- Lead Sponsor
- Fred Hutchinson Cancer Center
- Target Recruit Count
- 20
- Registration Number
- NCT00408681
- Locations
- 🇺🇸
Fred Hutchinson Cancer Research Center/University of Washington Cancer Consortium, Seattle, Washington, United States
Bipolar II Depression: Lithium, SSRI, or the Combination
- Conditions
- Interventions
- First Posted Date
- 2006-01-13
- Last Posted Date
- 2013-05-10
- Lead Sponsor
- Lindner Center of HOPE
- Target Recruit Count
- 139
- Registration Number
- NCT00276965
- Locations
- 🇺🇸
UCLA, Los Angeles, California, United States
🇺🇸Stanford University - Bipolar Research Program, Palo Alto, California, United States
🇺🇸Lindner Center of HOPE, affliated with University of Cincinnati Medical Center, Mason, Ohio, United States
Effect of Lithium Carbonate on Low-Dose Radioiodine Therapy in Early Thyroid Cancer
- Conditions
- Interventions
- First Posted Date
- 2005-11-09
- Last Posted Date
- 2013-02-04
- Target Recruit Count
- 34
- Registration Number
- NCT00251316
- Locations
- 🇺🇸
National Institutes of Health Clinical Center, 9000 Rockville Pike, Bethesda, Maryland, United States
Valproate Efficacy in Cocaine-Bipolar Comorbidity
- Conditions
- Interventions
- First Posted Date
- 2005-10-17
- Last Posted Date
- 2016-10-17
- Lead Sponsor
- University of Miami
- Target Recruit Count
- 152
- Registration Number
- NCT00240110
- Locations
- 🇺🇸
University of Miami Miller School of Medicine, Miami, Florida, United States
🇺🇸University of Miami Miller School of Medicine, Department of Psychiatry, Miami, Florida, United States
Indicated Prevention of Psychotic Disorders With Low-dose Lithium
- Conditions
- First Posted Date
- 2005-09-20
- Last Posted Date
- 2013-05-30
- Lead Sponsor
- Melbourne Health
- Target Recruit Count
- 30
- Registration Number
- NCT00202306
- Locations
- 🇦🇺
ORYGEN Youth Health, PACE Clinic, Parkville, Victoria, Australia
Treatment of Geriatric Bipolar Mood Disorders: A Pilot Study
- Conditions
- First Posted Date
- 2005-09-15
- Last Posted Date
- 2005-09-15
- Lead Sponsor
- University of Pittsburgh
- Target Recruit Count
- 60
- Registration Number
- NCT00177567
- Locations
- 🇺🇸
University of Pittsubrgh Medical Center, Pittsburgh, Pennsylvania, United States
🇺🇸University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, United States
Lithium Cannabis Withdrawal Study
- Conditions
- First Posted Date
- 2005-06-15
- Last Posted Date
- 2007-09-27
- Lead Sponsor
- Sydney South West Area Health Service
- Target Recruit Count
- 25
- Registration Number
- NCT00114439
- Locations
- 🇦🇺
Corella Drug Treatment Service, Fairfield, New South Wales, Australia
Study of Outcome and Safety of Lithium, Divalproex and Risperidone for Mania in Children and Adolescents
- Conditions
- Interventions
- First Posted Date
- 2003-04-08
- Last Posted Date
- 2013-04-04
- Lead Sponsor
- Washington University School of Medicine
- Target Recruit Count
- 379
- Registration Number
- NCT00057681
- Locations
- 🇺🇸
University of Pittsburgh/WPIC, Pittsburgh, Pennsylvania, United States
🇺🇸Johns Hopkins Medical Center, Baltimore, Maryland, United States
🇺🇸Children's National Medical Center, Washington, District of Columbia, United States
Maintenance Therapies in Bipolar Disorders
- Conditions
- First Posted Date
- 1999-11-03
- Last Posted Date
- 2013-06-25
- Lead Sponsor
- University of Pittsburgh
- Registration Number
- NCT00000369
Drug Development Updates
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