Magnesium sulfate
- Generic Name
- Magnesium sulfate
- Brand Names
- Concept Ob, Suflave, Suprep Bowel Prep Kit, Tis-U-sol
- Drug Type
- Small Molecule
- Chemical Formula
- MgO4S
- CAS Number
- 7487-88-9
- Unique Ingredient Identifier
- ML30MJ2U7I
- Background
A small colorless crystal used as an anticonvulsant, a cathartic, and an electrolyte replenisher in the treatment of pre-eclampsia and eclampsia. It causes direct inhibition of action potentials in myometrial muscle cells. Excitation and contraction are uncoupled, which decreases the frequency and force of contractions. (From AMA Drug Evaluations Annual, 199...
- Indication
Used for immediate control of life-threatening convulsions in the treatment of severe toxemias (pre-eclampsia and eclampsia) of pregnancy and in the treatment of acute nephritis in children. Also indicated for replacement therapy in magnesium deficiency, especially in acute hypomagnesemia accompanied by signs of tetany similar to those of hypocalcemia. Also ...
- Associated Conditions
- Constipation, Convulsions, Hypomagnesemia, Torsades de Pointes, Barium poisoning, Severe Exacerbation of asthma
- Associated Therapies
- Bowel preparation therapy, Soaking aid for minor sprains and bruises
MgSO4 vs Metoclopramide for Headache in Pregnant Women
- First Posted Date
- 2008-03-11
- Last Posted Date
- 2012-12-25
- Lead Sponsor
- Women and Infants Hospital of Rhode Island
- Registration Number
- NCT00632606
- Locations
- 🇺🇸
Women and Infants Hospital of Rhode Island, Providence, Rhode Island, United States
Magnesium Sulphate in Perinatal Asphyxia
- Conditions
- Interventions
- First Posted Date
- 2007-11-04
- Last Posted Date
- 2016-10-14
- Lead Sponsor
- Sheri Kashmir Institute of Medical Sciences
- Target Recruit Count
- 40
- Registration Number
- NCT00553072
- Locations
- 🇮🇳
Sheri-Kashmir Institute of Medical Scienceds, Srinagar, Jammu and Kashmir, India
Magnesium Sulfate Versus Placebo for Tocolysis in PPROM
- Conditions
- Interventions
- First Posted Date
- 2007-04-20
- Last Posted Date
- 2016-08-19
- Lead Sponsor
- Regional Obstetrical Consultants
- Target Recruit Count
- 4
- Registration Number
- NCT00463736
- Locations
- 🇺🇸
Regional Obstetrical Consultants, Chattanooga, Tennessee, United States
The Effect of Magnesium Sulphate on the Time Course of Rocuronium Induced Neuromuscular Block
- Conditions
- Interventions
- First Posted Date
- 2006-12-04
- Last Posted Date
- 2011-09-19
- Lead Sponsor
- University Hospital, Geneva
- Target Recruit Count
- 80
- Registration Number
- NCT00405977
- Locations
- 🇨🇭
University Hospital of Geneva, Anesthesia Department, Geneva, Canton of Geneva, Switzerland
Calcium Gluconate and Magnesium Sulfate in Preventing Neurotoxicity Caused By Oxaliplatin in Patients Receiving Combination Chemotherapy for Stage II, Stage III, or Stage IV Colorectal Cancer That Has Been Completely Removed By Surgery
- Conditions
- Interventions
- First Posted Date
- 2006-04-21
- Last Posted Date
- 2016-08-11
- Lead Sponsor
- Alliance for Clinical Trials in Oncology
- Target Recruit Count
- 104
- Registration Number
- NCT00316914
- Locations
- 🇺🇸
Medical Oncology and Hematology Associates at John Stoddard Cancer Center, Des Moines, Iowa, United States
🇺🇸Mercy Cancer Center at Mercy Medical Center - Des Moines, Des Moines, Iowa, United States
🇺🇸Avera Cancer Institute, Sioux Falls, South Dakota, United States
MAST - Magnesium for Sickle Cell Acute Crisis in Children
- Conditions
- Interventions
- First Posted Date
- 2006-04-12
- Last Posted Date
- 2013-08-13
- Lead Sponsor
- The Hospital for Sick Children
- Target Recruit Count
- 120
- Registration Number
- NCT00313963
- Locations
- 🇨🇦
The Hospital for Sick Children, Toronto, Ontario, Canada
Trial of Magnesium Sulfate Tocolysis Versus Nifedipine Tocolysis in Women With Preterm Labor
- Conditions
- Interventions
- First Posted Date
- 2006-03-23
- Last Posted Date
- 2009-11-09
- Lead Sponsor
- University of Cincinnati
- Target Recruit Count
- 33
- Registration Number
- NCT00306462
- Locations
- 🇺🇸
University Hospital, Cincinnati, Ohio, United States
Magnesium Sulfate Versus Nifedipine for the Acute Tocolysis of Preterm Labor: A Prospective, Randomized Trial
- Conditions
- Interventions
- First Posted Date
- 2005-09-16
- Last Posted Date
- 2018-11-19
- Lead Sponsor
- Stanford University
- Target Recruit Count
- 192
- Registration Number
- NCT00185900
- Locations
- 🇺🇸
Stanford University School of Medicine, Stanford, California, United States
Magnesium Sulfate vs Placebo for Placental Abruption
- Conditions
- Interventions
- First Posted Date
- 2005-09-16
- Last Posted Date
- 2018-01-02
- Lead Sponsor
- Stanford University
- Target Recruit Count
- 30
- Registration Number
- NCT00186069
- Locations
- 🇺🇸
Stanford University School of Medicine, Stanford, California, United States
🇺🇸Santa Clara Valley Medical Center, San Jose, California, United States
Magnesium Sulfate Versus Indomethacin for Preterm Labor
- Conditions
- First Posted Date
- 2005-06-30
- Last Posted Date
- 2016-08-15
- Lead Sponsor
- University of Pennsylvania
- Registration Number
- NCT00116623
- Locations
- 🇺🇸
University of Pennsylvania, Philadelphia, Pennsylvania, United States
Drug Development Updates
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