Magnesium sulfate
- Generic Name
- Magnesium sulfate
- Brand Names
- Concept Ob, Suflave, Suprep Bowel Prep Kit, Tis-U-sol
- Drug Type
- Small Molecule
- Chemical Formula
- MgO4S
- CAS Number
- 7487-88-9
- Unique Ingredient Identifier
- ML30MJ2U7I
- Background
A small colorless crystal used as an anticonvulsant, a cathartic, and an electrolyte replenisher in the treatment of pre-eclampsia and eclampsia. It causes direct inhibition of action potentials in myometrial muscle cells. Excitation and contraction are uncoupled, which decreases the frequency and force of contractions. (From AMA Drug Evaluations Annual, 1992, p1083)
- Indication
Used for immediate control of life-threatening convulsions in the treatment of severe toxemias (pre-eclampsia and eclampsia) of pregnancy and in the treatment of acute nephritis in children. Also indicated for replacement therapy in magnesium deficiency, especially in acute hypomagnesemia accompanied by signs of tetany similar to those of hypocalcemia. Also used in uterine tetany as a myometriat relaxant.
- Associated Conditions
- Constipation, Convulsions, Hypomagnesemia, Torsades de Pointes, Barium poisoning, Severe Exacerbation of asthma
- Associated Therapies
- Bowel preparation therapy, Soaking aid for minor sprains and bruises
Magnesium Sulfate Combined With Intraarticular Cocktail Injection for Analgesia After Simultaneous Bilateral Total Knee Arthroplasty
- First Posted Date
- 2024-06-06
- Last Posted Date
- 2024-06-06
- Lead Sponsor
- Chang Gung Memorial Hospital
- Target Recruit Count
- 80
- Registration Number
- NCT06445829
The Effect of Outpatient Ketamine Infusion on Chronic Neuropathic Pain and PTSD
- Conditions
- Neuropathic PainPTSD
- Interventions
- First Posted Date
- 2024-05-16
- Last Posted Date
- 2025-02-25
- Lead Sponsor
- Margaux M. Salas, PhD
- Target Recruit Count
- 30
- Registration Number
- NCT06414356
- Locations
- 🇺🇸
Brooke Army Medical Center, San Antonio, Texas, United States
Epsom Salt Compresses to Relieve Perineal for Postpartum Care: a Clinical Trial
- First Posted Date
- 2024-05-01
- Last Posted Date
- 2024-12-19
- Lead Sponsor
- Antoine Roger
- Target Recruit Count
- 90
- Registration Number
- NCT06393608
- Locations
- 🇨🇦
Hôpital de Chicoutimi, Chicoutimi, Quebec, Canada
🇨🇦Hôpital Brome-Missisquoi-Perkins, Cowansville, Quebec, Canada
🇨🇦Hôpital Charles Lemoyne, Greenfield Park, Quebec, Canada
Effect of Intrathecal Magnesium Sulfate Versus Intravenous Magnesium Sulfate on Postoperative Pain After Abdominal Hysterectomy
- First Posted Date
- 2024-04-16
- Last Posted Date
- 2024-05-29
- Lead Sponsor
- Assiut University
- Target Recruit Count
- 90
- Registration Number
- NCT06367595
Magnesium Sulfate in Neonatal HIE"
- Conditions
- Neonates With HIE
- Interventions
- Other: placebo or standard treatment)
- First Posted Date
- 2024-04-02
- Last Posted Date
- 2024-04-02
- Lead Sponsor
- Sindh Institute of Child Health and Neonatology
- Target Recruit Count
- 102
- Registration Number
- NCT06342362
- Locations
- 🇵🇰
SICHN, Karachi, Sindh, Pakistan
Magnesium Sulfate as an Adjuvant to Propofol During Consious Sedation in Colonoscopy
- Conditions
- Intraoperative AnalgesiaMagnesium
- Interventions
- First Posted Date
- 2023-11-14
- Last Posted Date
- 2023-12-18
- Lead Sponsor
- Assiut University
- Target Recruit Count
- 60
- Registration Number
- NCT06131905
Intra-operative Magnesium Sulphate for Post-operative Pain in Patients Undergoing Total Abdominal Hysterectomy Under General Anesthesia
- Conditions
- Post-operative Pain
- Interventions
- Drug: Normal Saline
- First Posted Date
- 2023-09-07
- Last Posted Date
- 2024-12-31
- Lead Sponsor
- Tribhuvan University Teaching Hospital, Institute Of Medicine.
- Target Recruit Count
- 42
- Registration Number
- NCT06026527
- Locations
- 🇳🇵
Tribhuvan University Teaching Hospital, Kathmandu, Bagmati, Nepal
Magnesium Versus Prochlorperazine Versus Metoclopramide for Migraines
- Conditions
- MigraineHeadache
- Interventions
- First Posted Date
- 2023-08-01
- Last Posted Date
- 2024-10-07
- Lead Sponsor
- Wake Forest University Health Sciences
- Target Recruit Count
- 157
- Registration Number
- NCT05967442
- Locations
- 🇺🇸
Advocate Christ Medical Center, Oak Lawn, Illinois, United States
Nebulized Versus Intravenous Magnesium Sulfate in Treatment of Asthma Exacerbation
- First Posted Date
- 2023-06-18
- Last Posted Date
- 2023-06-18
- Lead Sponsor
- Beni-Suef University
- Target Recruit Count
- 123
- Registration Number
- NCT05908864
- Locations
- 🇪🇬
Faculty of Medicine Beni-suef university, Banī Suwayf, Egypt
Magnesium Sulfate on Postoperative Pain
- Conditions
- Postoperative Pain
- Interventions
- Drug: normal saline isotonic solution
- First Posted Date
- 2023-05-30
- Last Posted Date
- 2023-05-30
- Lead Sponsor
- Pamukkale University
- Target Recruit Count
- 68
- Registration Number
- NCT05880732
- Locations
- 🇹🇷
Pamukkale Univercity Medical School, Denizli, Turkey
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.