Magnesium sulfate
- Generic Name
- Magnesium sulfate
- Brand Names
- Concept Ob, Suflave, Suprep Bowel Prep Kit, Tis-U-sol
- Drug Type
- Small Molecule
- Chemical Formula
- MgO4S
- CAS Number
- 7487-88-9
- Unique Ingredient Identifier
- ML30MJ2U7I
- Background
A small colorless crystal used as an anticonvulsant, a cathartic, and an electrolyte replenisher in the treatment of pre-eclampsia and eclampsia. It causes direct inhibition of action potentials in myometrial muscle cells. Excitation and contraction are uncoupled, which decreases the frequency and force of contractions. (From AMA Drug Evaluations Annual, 1992, p1083)
- Indication
Used for immediate control of life-threatening convulsions in the treatment of severe toxemias (pre-eclampsia and eclampsia) of pregnancy and in the treatment of acute nephritis in children. Also indicated for replacement therapy in magnesium deficiency, especially in acute hypomagnesemia accompanied by signs of tetany similar to those of hypocalcemia. Also used in uterine tetany as a myometriat relaxant.
- Associated Conditions
- Constipation, Convulsions, Hypomagnesemia, Torsades de Pointes, Barium poisoning, Severe Exacerbation of asthma
- Associated Therapies
- Bowel preparation therapy, Soaking aid for minor sprains and bruises
Comparative Study Between the Analgesic Effect of Dexmedetomidine and Magnesium Sulfate As Adjuvant to Bupivacaine Using Ultrasound-Guided Transversus Abdominis Plane Block in Abdominal Hysterectomy : a Randomized Double-blinded Study
- Conditions
- Hysterectomy
- Interventions
- First Posted Date
- 2024-12-06
- Last Posted Date
- 2024-12-06
- Lead Sponsor
- Assiut University
- Target Recruit Count
- 64
- Registration Number
- NCT06720337
Magnesium Sulfate and Postoperative Hypercoagulability in Laparoscopic Gynecological Surgeries
- Conditions
- Magnesium SulfateThromboelastometry
- Interventions
- Other: Placebo Drug
- First Posted Date
- 2024-12-05
- Last Posted Date
- 2024-12-05
- Lead Sponsor
- Marianna Mavromati
- Target Recruit Count
- 60
- Registration Number
- NCT06717490
- Locations
- 🇬🇷
Aretaieion University Hospital, Athens, Attica, Greece
Comparison Between Botox and Magnesium Sulfate Effect in Treatment of Myofascial Pain Trigger Points Within the Masseter Muscle
- Conditions
- Myofacial PainTrigger Points, Myofascial
- Interventions
- First Posted Date
- 2024-11-06
- Last Posted Date
- 2024-11-11
- Lead Sponsor
- Misr University for Science and Technology
- Target Recruit Count
- 60
- Registration Number
- NCT06676475
- Locations
- 🇪🇬
Misr university for science and technology, GIza, Egypt
Evaluation of the Role of Magnesium in Prevention of AF Post Cardiac Surgery
- Conditions
- Atrial Fibrillation (AF)Post Cardiac Surgery PatientsMagnesium Sulfate
- Interventions
- Drug: Placebo
- First Posted Date
- 2024-11-05
- Last Posted Date
- 2025-05-06
- Lead Sponsor
- Ain Shams University
- Target Recruit Count
- 130
- Registration Number
- NCT06675500
- Locations
- 🇪🇬
Faculty of Medicine ,Ain Shams University, Cairo, Egypt
Intravenous Tramadol and Magnesium Sulphate for Prevention of Shivering
- Conditions
- Lower Extremity Chronic Venous UlcersVaricose Veins LegHernia
- Interventions
- First Posted Date
- 2024-09-25
- Last Posted Date
- 2024-09-25
- Lead Sponsor
- Al-Azhar University
- Target Recruit Count
- 180
- Registration Number
- NCT06612996
Lidocaine Versus Magnesium Sulphate in Management of Myofascial Pain Dysfunction Syndrome
- Conditions
- Myofascial Pain Dysfunction Syndrome
- Interventions
- First Posted Date
- 2024-09-13
- Last Posted Date
- 2024-09-19
- Lead Sponsor
- Misr University for Science and Technology
- Target Recruit Count
- 75
- Registration Number
- NCT06595017
Efficacy of Iontophoresis in Treating Lateral Epicondylitis Patients
- Conditions
- Lateral Epicondylitis
- Interventions
- Other: conventional therapy
- First Posted Date
- 2024-08-29
- Last Posted Date
- 2024-08-29
- Lead Sponsor
- NOUR ALI ABO EL ELAA FRAGHLY
- Target Recruit Count
- 40
- Registration Number
- NCT06578000
- Locations
- 🇪🇬
Faculty of Physical Therapy, Cairo, Egypt
MgSO4 as Adjuvants to Bupivacaine vs Neostigmine in TAP Block in Cesarean Section
- Conditions
- Cesarean Section
- Interventions
- Procedure: transversus abdominis plane (TAP) block in cesarean section
- First Posted Date
- 2024-07-22
- Last Posted Date
- 2024-07-22
- Lead Sponsor
- Assiut University
- Target Recruit Count
- 68
- Registration Number
- NCT06513013
Magnesium Sulfate as an Adjunctive Analgesic in Prostate Surgery
- First Posted Date
- 2024-06-27
- Last Posted Date
- 2025-04-23
- Lead Sponsor
- NYU Langone Health
- Target Recruit Count
- 110
- Registration Number
- NCT06477133
- Locations
- 🇺🇸
NYU Langone Health, New York, New York, United States
Post-CA Neuroprotection With Magnesium
- Conditions
- Cardiac ArrestReturn of Spontaneous Circulation
- Interventions
- Drug: Saline
- First Posted Date
- 2024-06-12
- Last Posted Date
- 2025-05-22
- Lead Sponsor
- NYU Langone Health
- Target Recruit Count
- 178
- Registration Number
- NCT06455514
- Locations
- 🇺🇸
NYU Langone Health, New York, New York, United States
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.