Magnesium sulfate
- Generic Name
- Magnesium sulfate
- Brand Names
- Concept Ob, Suflave, Suprep Bowel Prep Kit, Tis-U-sol
- Drug Type
- Small Molecule
- Chemical Formula
- MgO4S
- CAS Number
- 7487-88-9
- Unique Ingredient Identifier
- ML30MJ2U7I
- Background
A small colorless crystal used as an anticonvulsant, a cathartic, and an electrolyte replenisher in the treatment of pre-eclampsia and eclampsia. It causes direct inhibition of action potentials in myometrial muscle cells. Excitation and contraction are uncoupled, which decreases the frequency and force of contractions. (From AMA Drug Evaluations Annual, 1992, p1083)
- Indication
Used for immediate control of life-threatening convulsions in the treatment of severe toxemias (pre-eclampsia and eclampsia) of pregnancy and in the treatment of acute nephritis in children. Also indicated for replacement therapy in magnesium deficiency, especially in acute hypomagnesemia accompanied by signs of tetany similar to those of hypocalcemia. Also used in uterine tetany as a myometriat relaxant.
- Associated Conditions
- Constipation, Convulsions, Hypomagnesemia, Torsades de Pointes, Barium poisoning, Severe Exacerbation of asthma
- Associated Therapies
- Bowel preparation therapy, Soaking aid for minor sprains and bruises
Comparisons Between Dexmedetomidine and Magnesium Sulfate in Controlled Hypotension During Rhinoplasty Surgeries
- First Posted Date
- 2023-05-30
- Last Posted Date
- 2023-05-31
- Lead Sponsor
- mohamed
- Target Recruit Count
- 56
- Registration Number
- NCT05880693
- Locations
- 🇪🇬
Mohamed gawad Abdel aboelsuod, Cairo, Egypt
Magnesium Sulphate and Extubation Quality
- Conditions
- Perioperative Complication
- Interventions
- Drug: Saline
- First Posted Date
- 2023-05-15
- Last Posted Date
- 2024-01-17
- Lead Sponsor
- Cukurova University
- Target Recruit Count
- 98
- Registration Number
- NCT05858957
- Locations
- 🇹🇷
Cukurova University, Adana, Turkey
Ketamine and Magnesium in Erector Spinae Plane Block
- Conditions
- Postoperative Analgesia
- Interventions
- First Posted Date
- 2023-05-11
- Last Posted Date
- 2023-11-03
- Lead Sponsor
- Cukurova University
- Target Recruit Count
- 60
- Registration Number
- NCT05855798
- Locations
- 🇹🇷
Cukurova University, Adana, Turkey
Efficacy of Esmolol Versus Magnesium Sulphate on Quality of Recovery in Patients Undergoing Laparoscopic Cholecystectomy: Randomized Controlled Study
- First Posted Date
- 2023-05-09
- Last Posted Date
- 2023-05-09
- Lead Sponsor
- Alexandria University
- Target Recruit Count
- 60
- Registration Number
- NCT05850832
- Locations
- 🇪🇬
Alexandria University Faculty of Medicin, Alexandria, Egypt
Dexmedetomidine, Ketamine and Magnesium Sulphate in Caudal Block for Hypospadias Repair
- Conditions
- DexmedetomidineKetamineHypospadiasPediatricsPreemptive AnalgesiaMagnesium Sulphate
- Interventions
- First Posted Date
- 2023-05-01
- Last Posted Date
- 2023-06-13
- Lead Sponsor
- Kafrelsheikh University
- Target Recruit Count
- 75
- Registration Number
- NCT05837000
- Locations
- 🇪🇬
Karelsheikh University Hospital, Kafr Ash Shaykh, Karelsheikh, Egypt
Magnesium Prophylaxis for the Prevention of New-Onset Atrial Fibrillation in Critically Ill Patients
- Conditions
- Critical IllnessNew Onset Atrial Fibrillation
- Interventions
- Drug: Placebo
- First Posted Date
- 2023-04-25
- Last Posted Date
- 2024-11-14
- Lead Sponsor
- Dr. Stephanie Sibley
- Target Recruit Count
- 140
- Registration Number
- NCT05829317
- Locations
- 🇨🇦
Kingston Health Sciences Centre, Kingston, Ontario, Canada
HUMAN CHORIONIC GONADOTROPIN (HcG) VS MAGNESIUM SULPHATE (MgSo4) AS A TOCOLYTIC AGENT- A RANDOMIZED CONTROLLED TRIAL
- Conditions
- Preterm Labor
- Interventions
- Drug: human chorionic gonadotropin (hCG)
- First Posted Date
- 2023-04-25
- Last Posted Date
- 2024-06-07
- Lead Sponsor
- Shaheed Zulfiqar Ali Bhutto Medical University
- Target Recruit Count
- 70
- Registration Number
- NCT05828966
- Locations
- 🇵🇰
Mother and Child Care Hospital, Shaheed Zulfiqar Ali Bhutto Medical University, Islamabad, Pakistan
Effect of MgSO4 Pretreatment on Muscle Relaxation
- First Posted Date
- 2023-03-07
- Last Posted Date
- 2024-07-01
- Lead Sponsor
- Assiut University
- Target Recruit Count
- 100
- Registration Number
- NCT05757999
- Locations
- 🇪🇬
Assiut university main hospital, ENT operative theatre, Asyut, Asyut Governorate, Egypt
The Effect of Peripartum Magnesium Sulfate Use on the Occurrence of Postpartum Depression
- First Posted Date
- 2023-03-02
- Last Posted Date
- 2023-03-02
- Lead Sponsor
- Seoul National University Bundang Hospital
- Target Recruit Count
- 108
- Registration Number
- NCT05751746
- Locations
- 🇰🇷
Seoul National University Bundang Hospital, Seongnam-si, Gyeonguido, Korea, Republic of
Dexmedetomidine Versus Magnesium Sulphate in Patients Undergoing Craniotomy for Deeply Settled Intracranial Tumours
- Conditions
- Brain Tumor
- Interventions
- First Posted Date
- 2023-02-24
- Last Posted Date
- 2023-02-24
- Lead Sponsor
- Assiut University
- Target Recruit Count
- 150
- Registration Number
- NCT05743725
- Locations
- 🇪🇬
Faculty of Medicine, Assiut University, Assiut, Egypt
Drug Development Updates
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