Misoprostol
- Generic Name
- Misoprostol
- Brand Names
- Arthrotec, Cytotec, Mifegymiso
- Drug Type
- Small Molecule
- Chemical Formula
- C22H38O5
- CAS Number
- 59122-46-2
- Unique Ingredient Identifier
- 0E43V0BB57
- Background
Misoprostol is a prostaglandin analog used to reduce the risk of NSAID related ulcers, manage miscarriages, prevent post partum hemorrhage, and also for first trimester abortions. The stimulation of prostaglandin receptors in the stomach reduces gastric acid secretion, while stimulating these receptors in the uterus and cervix can increase the strength and f...
- Indication
Misoprostol is indicated as a tablet to reduce the risk of NSAID induced gastric ulcers but not duodenal ulcers in high risk patients. Misoprostol is also formulated in combination with diclofenac to treat symptoms of osteoarthritis or rheumatoid arthritis in patients with a high risk of developing gastric ulcers. Misoprostol is used off label for the manage...
- Associated Conditions
- Gastric Ulcer, Incomplete Abortion, Missed Abortion, Postpartum Haemorrhage (PPH)
- Associated Therapies
- Induction of cervix ripening therapy, Medically induced abortion
Misoprostol Before Elective Caesarean Section for Decreasing the Neonatal Respiratory Morbidity
- Conditions
- Interventions
- First Posted Date
- 2017-01-25
- Last Posted Date
- 2018-05-29
- Lead Sponsor
- Ain Shams University
- Target Recruit Count
- 170
- Registration Number
- NCT03031353
- Locations
- 🇪🇬
Faculty of Medicine, Ain Shams University, Cairo, Al Qahirah, Egypt
Vaginal Misoprostol and Foley Catheter for Late Second Trimester Termination of Pregnancy
- Conditions
- Interventions
- First Posted Date
- 2016-12-12
- Last Posted Date
- 2018-02-07
- Lead Sponsor
- Zagazig University
- Target Recruit Count
- 97
- Registration Number
- NCT02989324
- Locations
- 🇪🇬
Zagazig University, Zagazig, Egypt
Acceptability and Feasibility of Medical Abortion in Singapore
- First Posted Date
- 2016-12-07
- Last Posted Date
- 2018-04-06
- Lead Sponsor
- Gynuity Health Projects
- Target Recruit Count
- 130
- Registration Number
- NCT02985229
- Locations
- 🇸🇬
KK Women's and Children's Hospital, Singapore, Singapore
🇸🇬National University Hospital, Singapore, Singapore
Acceptability and Feasibility of a Simplified Medical Abortion Service Delivery in Western Ukraine
- First Posted Date
- 2016-12-02
- Last Posted Date
- 2018-06-18
- Lead Sponsor
- Gynuity Health Projects
- Target Recruit Count
- 102
- Registration Number
- NCT02981030
- Locations
- 🇺🇦
Vinnitsa Regional Clinical Hospital, Vinnitsa, Ukraine
🇺🇦Lviv Municipal Women's Consultation No. 2, L'viv, Ukraine
Vaginal Misoprostol and Foley Catheter for Induction of Labor
- Conditions
- Interventions
- First Posted Date
- 2016-11-02
- Last Posted Date
- 2017-06-16
- Lead Sponsor
- Zagazig University
- Target Recruit Count
- 160
- Registration Number
- NCT02952807
- Locations
- 🇪🇬
Zagazig University, Zagazig, Egypt
Vaginal Misodel® in Comparison With Orally Administrated Misoprostol (Cytotec®) at Induction of Labour
- First Posted Date
- 2016-09-28
- Last Posted Date
- 2016-09-28
- Lead Sponsor
- Karolinska Institutet
- Target Recruit Count
- 320
- Registration Number
- NCT02918110
- Locations
- 🇸🇪
Eva Wiberg-Itzel, Stockholm, Sweden
Misoprostol as First Aid Measure to Address Excessive Postpartum Bleeding
- Conditions
- First Posted Date
- 2016-08-03
- Last Posted Date
- 2016-08-03
- Lead Sponsor
- Gynuity Health Projects
- Target Recruit Count
- 4330
- Registration Number
- NCT02853552
Effectiveness of Tranexamic Acid When Used as an Adjunct to Misoprostol for the Treatment of Postpartum Hemorrhage
- Conditions
- Interventions
- First Posted Date
- 2016-06-20
- Last Posted Date
- 2018-02-19
- Lead Sponsor
- Gynuity Health Projects
- Target Recruit Count
- 260
- Registration Number
- NCT02805426
- Locations
- 🇻🇳
Hung Vuong Hospital, Ho Chi Minh City, Vietnam
🇸🇳Centre hospitalier Régional de Thiès, Ahmadou Sakhir Ndiéguène, Thiès, Senegal
🇻🇳National OB-GYN Hospital, Hanoi, Vietnam
Effect of Maternal Obesity on Labour Induction in Postdate Pregnancy
- First Posted Date
- 2016-06-02
- Last Posted Date
- 2017-10-16
- Lead Sponsor
- Kasr El Aini Hospital
- Target Recruit Count
- 288
- Registration Number
- NCT02788305
- Locations
- 🇪🇬
Kasr wl aini hospitals, Cairo, Greater Cairo, Egypt
Misoprostol+Oxytocin vs. Carbetocin in CS
- Conditions
- Interventions
- First Posted Date
- 2016-06-01
- Last Posted Date
- 2020-07-08
- Lead Sponsor
- Ain Shams University
- Target Recruit Count
- 600
- Registration Number
- NCT02786992
- Locations
- 🇪🇬
Ain Shams University Maternity Hospital, Cairo, Egypt
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.