Misoprostol
- Generic Name
- Misoprostol
- Brand Names
- Arthrotec, Cytotec, Mifegymiso
- Drug Type
- Small Molecule
- Chemical Formula
- C22H38O5
- CAS Number
- 59122-46-2
- Unique Ingredient Identifier
- 0E43V0BB57
- Background
Misoprostol is a prostaglandin analog used to reduce the risk of NSAID related ulcers, manage miscarriages, prevent post partum hemorrhage, and also for first trimester abortions. The stimulation of prostaglandin receptors in the stomach reduces gastric acid secretion, while stimulating these receptors in the uterus and cervix can increase the strength and f...
- Indication
Misoprostol is indicated as a tablet to reduce the risk of NSAID induced gastric ulcers but not duodenal ulcers in high risk patients. Misoprostol is also formulated in combination with diclofenac to treat symptoms of osteoarthritis or rheumatoid arthritis in patients with a high risk of developing gastric ulcers. Misoprostol is used off label for the manage...
- Associated Conditions
- Gastric Ulcer, Incomplete Abortion, Missed Abortion, Postpartum Haemorrhage (PPH)
- Associated Therapies
- Induction of cervix ripening therapy, Medically induced abortion
Preoperative and Postoperative Sublingual Misoprostol for Prevention of Postpartum Blood Loss in Cesarean Section
- First Posted Date
- 2018-07-19
- Last Posted Date
- 2018-09-18
- Lead Sponsor
- Assiut University
- Target Recruit Count
- 500
- Registration Number
- NCT03591913
- Locations
- 🇪🇬
Ahmed Abbas, Assiut, Cairo, Egypt
Pain Relief During IUD Insertion in Women Delivered Only by Elective Cesarean Section
- Conditions
- Interventions
- First Posted Date
- 2018-07-16
- Last Posted Date
- 2018-07-16
- Lead Sponsor
- Assiut University
- Target Recruit Count
- 113
- Registration Number
- NCT03587077
CARBETOCIN VERSUS RECTAL MISOPROSTOL FOR MANAGEMENT OF THIRD STAGE OF LABOR IN WOMEN AT LOW RISK OF POSTPARTUM HEMORRHAGE
- First Posted Date
- 2018-06-14
- Last Posted Date
- 2019-10-11
- Lead Sponsor
- Cairo University
- Target Recruit Count
- 150
- Registration Number
- NCT03556852
- Locations
- 🇪🇬
Kasr Alainy medical school, Cairo, Egypt
Medical Abortion With Single Daily Dose of Misoprostol
- First Posted Date
- 2018-04-04
- Last Posted Date
- 2019-01-29
- Lead Sponsor
- Ain Shams University
- Target Recruit Count
- 200
- Registration Number
- NCT03487354
- Locations
- 🇪🇬
Ain Shams University Maternity Hospital, Cairo, Egypt
the Effect of Misoprostol on Intra-operative Blood Loss During Myomectomy Operation
- First Posted Date
- 2018-03-30
- Last Posted Date
- 2018-05-18
- Lead Sponsor
- ahmed nagy shaker ramadan
- Target Recruit Count
- 50
- Registration Number
- NCT03483142
- Locations
- 🇪🇬
Ain Shams Maternity Hospital, Cairo, Abbasia, Egypt
Estradiol Pretreatment With Misoprostol in Second Trimester Miscarriage
- Conditions
- Interventions
- First Posted Date
- 2018-03-27
- Last Posted Date
- 2019-01-29
- Lead Sponsor
- Ain Shams University
- Target Recruit Count
- 200
- Registration Number
- NCT03479879
- Locations
- 🇪🇬
Ain Shams University Maternity Hospital, Cairo, Egypt
Misoprosotol and Isosorbide Mononitrate for Induction of Second Trimester Abortion
- Conditions
- Interventions
- First Posted Date
- 2018-01-23
- Last Posted Date
- 2018-02-28
- Lead Sponsor
- Ain Shams University
- Target Recruit Count
- 60
- Registration Number
- NCT03407521
- Locations
- 🇪🇬
Faculty of Medicine Ain Shams University, Cairo, Egypt
Different Methods of Termination of Second Trimester Abortion
- Conditions
- Interventions
- First Posted Date
- 2018-01-17
- Last Posted Date
- 2018-01-25
- Lead Sponsor
- Cairo University
- Target Recruit Count
- 150
- Registration Number
- NCT03400683
- Locations
- 🇪🇬
Kasr Alainy medical school, Cairo, Egypt
A Trial for Peroperative Procedure and Postoperative Pain After Rectal Misoprostol or Rectal Hyoscine Administration
- Conditions
- Interventions
- First Posted Date
- 2017-12-02
- Last Posted Date
- 2018-12-27
- Lead Sponsor
- Bezmialem Vakif University
- Target Recruit Count
- 120
- Registration Number
- NCT03359655
- Locations
- 🇹🇷
Bezmialem Vakif University, Istanbul, Turkey
Mifepristone and Misoprostol for 2nd Trimester Termination of Pregnancy in Burkina Faso
- First Posted Date
- 2017-08-31
- Last Posted Date
- 2019-05-30
- Lead Sponsor
- Gynuity Health Projects
- Target Recruit Count
- 100
- Registration Number
- NCT03269279
- Locations
- 🇧🇫
CHUYO, Ouagadougou, Burkina Faso
🇧🇫CMA Boromo, Boromo, Burkina Faso
🇧🇫CHR Ouahigouya, Ouahigouya, Burkina Faso
Drug Development Updates
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