Clonidine
- Generic Name
- Clonidine
- Brand Names
- Catapres, Catapres-TTS, Catapres-tts-1, Duraclon, Kapvay, Nexiclon XR
- Drug Type
- Small Molecule
- Chemical Formula
- C9H9Cl2N3
- CAS Number
- 4205-90-7
- Unique Ingredient Identifier
- MN3L5RMN02
- Background
Clonidine is an imidazole derivate that acts as an agonist of alpha-2 adrenoceptors. This activity is useful for the treatment of hypertension, severe pain, and ADHD.
Clonidine was granted FDA approval on 3 September 1974.
- Indication
Clonidine tablets and transdermal systems are indicated for the treatment of hypertension alone or in combination with other medications. A clonidine injection is indicated for use with opiates in the treatment of severe cancer pain where opiates alone are insufficient. An extended release tablet of clonidine is indicated for the treatment of ADHD either alo...
- Associated Conditions
- Attention Deficit Hyperactivity Disorder (ADHD), Defiant Disorder, Oppositional, Gilles de la Tourette's Syndrome, Hot Flashes, Human Growth Hormone Deficiency, Hypertension, Opioid Withdrawal (Disorder), Pheochromocytoma, Postherpetic Neuralgia, Sialorrhea caused by clozapine, Diabetic diarrhea, Methadone withdrawal, Severe Cancer pain
- Associated Therapies
- Smoking, Cessation
Dexamethasone or Clonidine as Adjuncts to Ropivacaine for Caudal Analgesia on Analgesia Duration in Children
- Conditions
- Interventions
- First Posted Date
- 2016-05-16
- Last Posted Date
- 2016-05-16
- Target Recruit Count
- 155
- Registration Number
- NCT02773602
- Locations
- 🇺🇸
Memorial Hermann Hospital, Houston, Texas, United States
Evaluate Use of Caudal Nerve Blocks in Adult Penile Prosthesis
- First Posted Date
- 2016-04-15
- Last Posted Date
- 2022-01-24
- Lead Sponsor
- M.D. Anderson Cancer Center
- Target Recruit Count
- 52
- Registration Number
- NCT02740127
- Locations
- 🇺🇸
University of Texas MD Anderson Cancer Center, Houston, Texas, United States
Clonidine Added Lidocaine in Intraocular Pressure and Hemodynamics Ocular in Sub-Tenon's and Peribulbar Anesthesia
- First Posted Date
- 2016-04-11
- Last Posted Date
- 2020-08-25
- Lead Sponsor
- Federal University of Minas Gerais
- Target Recruit Count
- 80
- Registration Number
- NCT02733757
Effectiveness of Ultrasound Guided Adductor Canal Block on Chronic Pain in Knee Osteoarthritis
- First Posted Date
- 2016-03-01
- Last Posted Date
- 2016-11-08
- Lead Sponsor
- Mensur Salihovic
- Target Recruit Count
- 77
- Registration Number
- NCT02695654
- Locations
- 🇸🇮
University Medical Centre, Ljubljana, Slovenia
Double-blind Study to Assess effectIveness of Pectoral Nerves Block After Breast Surgery on Piritramide Consumption
- Conditions
- Interventions
- First Posted Date
- 2016-01-14
- Last Posted Date
- 2021-01-27
- Lead Sponsor
- Jules Bordet Institute
- Target Recruit Count
- 54
- Registration Number
- NCT02655965
- Locations
- 🇧🇪
Institut Jules Bordet, Bruxelles, Belgium
Utility of Olanzapine in the Treatment of Opioid Withdrawal in the ED
- Conditions
- Interventions
- First Posted Date
- 2015-12-31
- Last Posted Date
- 2019-07-10
- Lead Sponsor
- Hennepin Healthcare Research Institute
- Target Recruit Count
- 70
- Registration Number
- NCT02643355
- Locations
- 🇺🇸
Hennepin County Medical Center, Minneapolis, Minnesota, United States
A Study of Colesevelam in Fecal Incontinence
- Conditions
- Interventions
- First Posted Date
- 2015-12-11
- Last Posted Date
- 2023-06-22
- Lead Sponsor
- Mayo Clinic
- Target Recruit Count
- 88
- Registration Number
- NCT02628626
- Locations
- 🇺🇸
Mayo Clinic Rochester, Rochester, Minnesota, United States
Postoperative Pain Control After Periarticular Injection During Total Knee Arthroplasty
- Conditions
- Interventions
- First Posted Date
- 2015-10-07
- Last Posted Date
- 2022-03-04
- Lead Sponsor
- Virginia Commonwealth University
- Target Recruit Count
- 64
- Registration Number
- NCT02570503
- Locations
- 🇺🇸
Virginia Commonwealth University, Richmond, Virginia, United States
Programmed Intermittent Epidural Bolus Versus Continuous Epidural Infusion for Third Trimester Medical Termination of Pregnancy Analgesia : a Randomized Study. (PCEA-IMG)
- First Posted Date
- 2015-09-30
- Last Posted Date
- 2019-01-22
- Lead Sponsor
- University Hospital, Limoges
- Target Recruit Count
- 37
- Registration Number
- NCT02563821
- Locations
- 🇫🇷
Universiy hospital, Limoges, France
Improving Treatment Outcomes for Prescription Opioid Dependence
- Conditions
- Interventions
- First Posted Date
- 2015-09-07
- Last Posted Date
- 2022-07-28
- Lead Sponsor
- University of Arkansas
- Target Recruit Count
- 117
- Registration Number
- NCT02543944
- Locations
- 🇺🇸
University of Arkansas for Medical Sciences, Little Rock, Arkansas, United States
Drug Development Updates
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