Neomycin
- Generic Name
- Neomycin
- Brand Names
- Casporyn HC, Cortisporin, Cortisporin-TC, Dioptrol, Diosporin, Diphen, Maxitrol, Neo-polycin, Neo-polycin HC, Neo-synalar, Neosporin Ointment, Neosporin Plus Maximum Strength, Neosporin Plus Maximum Strength Cream, Neosporin Solution, Procomycin, Statrol, Triple Antibiotic, Viaderm Kc
- Drug Type
- Small Molecule
- Chemical Formula
- -
- CAS Number
- 1404-04-2
- Unique Ingredient Identifier
- I16QD7X297
- Background
Neomycin is a broad-spectrum aminoglycoside antibiotic drug that is derived from the metabolic products of Streptomyces fradiae. Neomycin is a complex comprised of three components, neomycin A, B, and C. Neomycin B, also known as framycetin, is the most active component of the complex and neomycin C is the isomer of neomycin B, making these two stereoisomers...
- Indication
Oral neomycin sulfate is indicated as an adjunctive therapy in hepatic coma (portal-system encephalopathy) by reducing ammonia-forming bacteria in the intestinal tract. It is strongly recommended that oral neomycin is only used in infections that are proven or strongly suspected to be caused by susceptible bacteria to reduce the risk of the development of dr...
- Associated Conditions
- Allergic Contact Dermatitis, Allergic Skin Reaction, Atopic Dermatitis, Atopic Dermatitis (AD) of the external ear canal, Bacterial diarrhoea, Burns, Carbuncle, Contact Dermatitis, Cradle Cap, Dermatitis, Diarrhea, Discoid Lupus Erythematosus (DLE), Ear infection bacterial, Ear infection bacterial caused by susceptible bacteria, Gastrointestinal Tract Infections, Hepatic coma, Hidradenitis Suppurativa (HS), Hot Water Burns (Scalds), Impetigo, Impetigo contagious, Infantile Eczema, Infected skin ulcer, Infection of the outer ear caused by susceptible bacteria, Infectious diarrhea, Inflammatory Reaction caused by Acne, Intertrigo, Itching caused by Infection, Lichen Planus (LP), Localized Infection caused by susceptible bacteria, Nail infection, Neurodermatitis, Otitis Externa, Postoperative Wound Infection, Psoriasis Vulgaris (Plaque Psoriasis), Pustular Dermatosis, Pustular acne, Radiodermatitis, Secondarily Infected Eczema, Secondary Bacterial Infection, Skin Burn, Skin Infections, Skin Irritation, Skin Ulcer, Solar erythema, Wound Infections, Abrasions, Bacterial skin infections, Blistering caused by Staphylococcus, Erythematous eruptions, Intertriginous erythema of the anogenital, Ocular bacterial infections caused by susceptible bacteria, Resistant to other corticosteroids Dermatosis, Susceptible Bacterial Infections
- Associated Therapies
- -
Decolonization of Carbapenem-resistant Enterobacterales (CRE) in Patients With Faecal Carriage of CRE With Neomycin
- First Posted Date
- 2022-10-25
- Last Posted Date
- 2022-11-30
- Lead Sponsor
- Mahidol University
- Target Recruit Count
- 60
- Registration Number
- NCT05593601
- Locations
- 🇹🇭
Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand
Fecal Microbiota Transplant and Re-introduction of Anti-PD-1 Therapy (Pembrolizumab or Nivolumab) for the Treatment of Metastatic Colorectal Cancer in Anti-PD-1 Non-responders
- Conditions
- Interventions
- First Posted Date
- 2021-01-28
- Last Posted Date
- 2024-12-12
- Lead Sponsor
- M.D. Anderson Cancer Center
- Target Recruit Count
- 15
- Registration Number
- NCT04729322
- Locations
- 🇺🇸
M D Anderson Cancer Center, Houston, Texas, United States
Bowel Preparation in Elective Pediatric Colorectal Surgery
- Conditions
- Interventions
- First Posted Date
- 2018-07-20
- Last Posted Date
- 2021-12-09
- Lead Sponsor
- McMaster University
- Target Recruit Count
- 81
- Registration Number
- NCT03593252
Pilot Study of Fundamental Modification of the Gut Microbiota in the Treatment of Refractory Crohn's Disease
- Conditions
- Interventions
- First Posted Date
- 2018-03-26
- Last Posted Date
- 2022-02-09
- Lead Sponsor
- Children's Hospital of Philadelphia
- Target Recruit Count
- 10
- Registration Number
- NCT03476317
- Locations
- 🇺🇸
Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, United States
Neomycin and Metronidazole Hydrochloride With or Without Polyethylene Glycol in Reducing Infection in Patients Undergoing Elective Colorectal Surgery
- First Posted Date
- 2017-02-03
- Last Posted Date
- 2018-08-22
- Lead Sponsor
- Thomas Jefferson University
- Target Recruit Count
- 224
- Registration Number
- NCT03042091
- Locations
- 🇺🇸
Thomas Jefferson University, Philadelphia, Pennsylvania, United States
Fundamental Modification of the Gut Microbiota in the Treatment of Refractory Crohn's Disease
- Conditions
- Interventions
- First Posted Date
- 2016-05-06
- Last Posted Date
- 2024-02-06
- Lead Sponsor
- University of Pennsylvania
- Target Recruit Count
- 8
- Registration Number
- NCT02765256
- Locations
- 🇺🇸
University of Pennsylvania, Philadelphia, Pennsylvania, United States
Interventional Bioremediation of Microbiota in Metabolic Syndrome
- Conditions
- Interventions
- First Posted Date
- 2016-04-07
- Last Posted Date
- 2023-02-22
- Lead Sponsor
- University of Minnesota
- Target Recruit Count
- 12
- Registration Number
- NCT02730962
- Locations
- 🇺🇸
University of Minnesota Medical Center, Minneapolis, Minnesota, United States
Efficacy of Intestinal Decontamination in Patients Colonized by Carbapenem-resistant Klebsiella Pneumoniae and Colistin
- Conditions
- Interventions
- First Posted Date
- 2015-11-13
- Last Posted Date
- 2015-11-13
- Target Recruit Count
- 44
- Registration Number
- NCT02604849
Eradication of Antibiotic-resistant Bacteria Through Antibiotics and Fecal Bacteriotherapy
- First Posted Date
- 2015-06-16
- Last Posted Date
- 2017-12-07
- Lead Sponsor
- Stephen Harbarth
- Target Recruit Count
- 39
- Registration Number
- NCT02472600
- Locations
- 🇫🇷
Assistance Publique-Hôpitaux de Paris, Hôpital Beaujon, Clichy, France
🇳🇱Universitair Medisch Centrum Utrecht,, Utrecht, Netherlands
🇨🇭Geneva University Hospitals, Geneva, Switzerland
Systems Biology of Flu Vaccine in Healthy Adults With and Without the Use of Antibiotics
- Conditions
- Interventions
- First Posted Date
- 2014-06-03
- Last Posted Date
- 2018-08-15
- Lead Sponsor
- Emory University
- Target Recruit Count
- 33
- Registration Number
- NCT02154061
- Locations
- 🇺🇸
Emory Vaccine Center, Atlanta, Georgia, United States
Drug Development Updates
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