Methylprednisolone hemisuccinate
- Generic Name
- Methylprednisolone hemisuccinate
- Brand Names
- Solu-medrol
- Drug Type
- Small Molecule
- Chemical Formula
- C26H34O8
- CAS Number
- 2921-57-5
- Unique Ingredient Identifier
- 5GMR90S4KN
- Background
A water-soluble ester of methylprednisolone used for cardiac, allergic, and hypoxic emergencies.
- Associated Conditions
- Acute Gouty Arthritis, Ankylosing Spondylitis (AS), Berylliosis, Congenital Adrenal Hyperplasia (CAH), Congenital Hypoplastic Anemia, Dermatitis bullous, Dermatomyositis (DM), Edema of the cerebrum, Hypercalcemia of Malignancy, Immune Thrombocytopenia (ITP), Leukemias, Lymphoma, Multiple sclerosis exacerbation, Mycosis Fungoides (MF), Ophthalmia, Sympathetic, Pemphigus, Polymyositis, Primary adrenocortical insufficiency, Psoriatic Arthritis, Pure Red Cell Aplasia, Refractory Uveitis, Regional Enteritis, Rheumatoid Arthritis, Secondary adrenocortical insufficiency, Secondary thrombocytopenia, Stevens-Johnson Syndrome, Systemic Lupus Erythematosus, Temporal Arteritis, Trichinosis, Tuberculous Meningitis, Ulcerative Colitis, Acquired immune hemolytic anemia, Acute rheumatic carditis, Disseminated Pulmonary Tuberculosis (TB), Exfoliative erythroderma, Fulminating Pulmonary Tuberculosis, Idiopathic eosinophilic pneumonias, Non-suppurative Thyroiditis, Severe Allergic Reactions, Symptomatic Sarcoidosis
- Associated Therapies
- Palliative Treatment
Sequential Therapy With Tacrolimus and Rituximab in Primary Membranous Nephropathy
- Conditions
- Interventions
- First Posted Date
- 2013-10-07
- Last Posted Date
- 2020-01-18
- Lead Sponsor
- Hospital Universitario 12 de Octubre
- Target Recruit Count
- 86
- Registration Number
- NCT01955187
- Locations
- 🇪🇸
Hospital 12 de Octubre, Madrid, Spain
Evaluation of Inhaled Treatment in Sinusitis
- First Posted Date
- 2013-07-24
- Last Posted Date
- 2014-01-27
- Target Recruit Count
- 50
- Registration Number
- NCT01907204
Phase 1 PK Interaction Study Between VX-509 and Prednisone or Methylprednisolone in Healthy Male Subjects
- Conditions
- Interventions
- First Posted Date
- 2013-06-25
- Last Posted Date
- 2013-08-14
- Lead Sponsor
- Vertex Pharmaceuticals Incorporated
- Target Recruit Count
- 28
- Registration Number
- NCT01886209
- Locations
- 🇺🇸
Vertex Investigational Site, Lenexa, Kansas, United States
Immunosuppression in Amyotrophic Lateral Sclerosis (ALS)
- Conditions
- Interventions
- First Posted Date
- 2013-06-24
- Last Posted Date
- 2017-11-06
- Lead Sponsor
- Emory University
- Target Recruit Count
- 31
- Registration Number
- NCT01884571
- Locations
- 🇺🇸
Emory University, Atlanta, Georgia, United States
🇺🇸University of Massachusetts Medical School, Worcester, Massachusetts, United States
🇺🇸Massachusetts General Hospital, Boston, Massachusetts, United States
Donor Lymphocyte Infusion (DLI) of T-cells Genetically Modified With iCasp9 Suicide Gene
- Conditions
- Interventions
- First Posted Date
- 2013-06-11
- Last Posted Date
- 2019-07-16
- Lead Sponsor
- M.D. Anderson Cancer Center
- Target Recruit Count
- 3
- Registration Number
- NCT01875237
- Locations
- 🇺🇸
University of Texas MD Anderson Cancer Center, Houston, Texas, United States
Open-Label Phase 2 Trial of a Steroid-Free, CNI-Free, Belatacept-Based Immunosuppressive Regimen
- First Posted Date
- 2013-05-17
- Last Posted Date
- 2020-12-17
- Target Recruit Count
- 71
- Registration Number
- NCT01856257
- Locations
- 🇺🇸
Emory University, Atlanta, Georgia, United States
🇺🇸University of Alabama at Birmingham, Birmingham, Alabama, United States
🇺🇸University of California, San Francisco, San Francisco, California, United States
Safety and Efficacy of Nonsteroidal Antiinflammatory (NSAI)Drug and Glucocorticoids in Acute Sciatica
- Conditions
- Interventions
- First Posted Date
- 2013-03-22
- Last Posted Date
- 2016-03-24
- Lead Sponsor
- University Hospital, Grenoble
- Target Recruit Count
- 50
- Registration Number
- NCT01816334
- Locations
- 🇫🇷
CH d'Uriage, Uriage, France
🇫🇷CHU Hôpital Sud, Echirolles, France
Efficacy Study of Anakinra, Pentoxifylline, and Zinc Compared to Methylprednisolone in Severe Acute Alcoholic Hepatitis
- Conditions
- Interventions
- First Posted Date
- 2013-03-12
- Last Posted Date
- 2021-11-01
- Lead Sponsor
- Mack Mitchell
- Target Recruit Count
- 104
- Registration Number
- NCT01809132
- Locations
- 🇺🇸
University of Louisville, Louisville, Kentucky, United States
🇺🇸University of Texas Southwestern Medical Center, Dallas, Texas, United States
🇺🇸Cleveland Clinic, Cleveland, Ohio, United States
Single Dose of Etomidate and Adrenal Cortex
- Conditions
- Interventions
- First Posted Date
- 2013-02-15
- Last Posted Date
- 2013-08-26
- Lead Sponsor
- Istanbul University
- Target Recruit Count
- 90
- Registration Number
- NCT01792037
- Locations
- 🇹🇷
Cerrahpasa Medical Faculty Anesthesiology and Reanimation Department, Istanbul, Fatih, Turkey
Optimization of NULOJIX® Usage Towards Minimizing CNI Exposure in Simultaneous Pancreas and Kidney Transplantation
- First Posted Date
- 2013-02-13
- Last Posted Date
- 2021-07-20
- Target Recruit Count
- 46
- Registration Number
- NCT01790594
- Locations
- 🇺🇸
Emory University, Atlanta, Georgia, United States
🇺🇸University of Wisconsin, Madison, Wisconsin, United States
🇺🇸Indiana University Hospital, Indianapolis, Indiana, United States
Drug Development Updates
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