Methylprednisolone hemisuccinate

Generic Name
Methylprednisolone hemisuccinate
Brand Names
Solu-medrol
Drug Type
Small Molecule
Chemical Formula
C26H34O8
CAS Number
2921-57-5
Unique Ingredient Identifier
5GMR90S4KN
Background

A water-soluble ester of methylprednisolone used for cardiac, allergic, and hypoxic emergencies.

Associated Conditions
Acute Gouty Arthritis, Ankylosing Spondylitis (AS), Berylliosis, Congenital Adrenal Hyperplasia (CAH), Congenital Hypoplastic Anemia, Dermatitis bullous, Dermatomyositis (DM), Edema of the cerebrum, Hypercalcemia of Malignancy, Immune Thrombocytopenia (ITP), Leukemias, Lymphoma, Multiple sclerosis exacerbation, Mycosis Fungoides (MF), Ophthalmia, Sympathetic, Pemphigus, Polymyositis, Primary adrenocortical insufficiency, Psoriatic Arthritis, Pure Red Cell Aplasia, Refractory Uveitis, Regional Enteritis, Rheumatoid Arthritis, Secondary adrenocortical insufficiency, Secondary thrombocytopenia, Stevens-Johnson Syndrome, Systemic Lupus Erythematosus, Temporal Arteritis, Trichinosis, Tuberculous Meningitis, Ulcerative Colitis, Acquired immune hemolytic anemia, Acute rheumatic carditis, Disseminated Pulmonary Tuberculosis (TB), Exfoliative erythroderma, Fulminating Pulmonary Tuberculosis, Idiopathic eosinophilic pneumonias, Non-suppurative Thyroiditis, Severe Allergic Reactions, Symptomatic Sarcoidosis
Associated Therapies
Palliative Treatment
Clinical Trials
Related News

Clofarabine or High-Dose Cytarabine and Pegaspargase in Children with ALL

First Posted Date
2010-10-26
Last Posted Date
2024-12-11
Lead Sponsor
Universitätsklinikum Hamburg-Eppendorf
Target Recruit Count
745
Registration Number
NCT01228331
Locations
🇩🇪

Universitaetsklinikum Duesseldorf, Duesseldorf, Germany

🇩🇪

University Medical Center Hamburg - Eppendorf, Hamburg, Germany

🇩🇪

Johannes Gutenberg University, Mainz, Germany

and more 11 locations

A Study of Glucocorticoid Use to Evaluate Systematic Methylprednisolone Reduction in Patients With Rheumatoid Arthritis on Background RoActemra/Actemra (Tocilizumab) (ACT-ALONE)

First Posted Date
2010-10-13
Last Posted Date
2015-01-19
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
68
Registration Number
NCT01219933

Methylprednisolone Pulse Macrolide Therapy for Refractory Mycoplasma Pneumoniae Pneumonia in Children

First Posted Date
2010-10-08
Last Posted Date
2010-10-08
Lead Sponsor
Chongqing Medical University
Target Recruit Count
47
Registration Number
NCT01217099

Seronegative Oligoarthritis of the Knee Study (SOKS)

Phase 2
Terminated
Conditions
Spondylarthropathies
Interventions
Drug: methylprednisolone
Drug: Infliximab
First Posted Date
2010-10-07
Last Posted Date
2016-05-13
Lead Sponsor
University of Leeds
Target Recruit Count
1
Registration Number
NCT01216631
Locations
🇬🇧

Leeds Teaching Hospitals NHS Trust, Leeds, West Yorkshire, United Kingdom

Corticosteroids for Immune Reconstitution Inflammatory Syndrome (IRIS)

First Posted Date
2010-09-29
Last Posted Date
2014-09-05
Lead Sponsor
Biogen
Target Recruit Count
3
Registration Number
NCT01211665
Locations
🇩🇪

Research Site, Wurzburg, Germany

Systemic Methylprednisolone in Chronic Rhinosinusitis

Phase 4
Completed
Conditions
Chronic Rhinosinusitis
Children
Interventions
Drug: methylprednisolone
First Posted Date
2010-09-21
Last Posted Date
2010-09-21
Lead Sponsor
Ondokuz Mayıs University
Target Recruit Count
48
Registration Number
NCT01205984
Locations
🇹🇷

Gazi University Faculty of Medicine, Ankara, Turkey

Penostatin, Rituximab and Ontak and Allogeneic Natural Killer (NK) Cells for Refractory Lymphoid Malignancies

First Posted Date
2010-08-13
Last Posted Date
2018-02-06
Lead Sponsor
Masonic Cancer Center, University of Minnesota
Target Recruit Count
16
Registration Number
NCT01181258
Locations
🇺🇸

Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota, United States

High-Dose Busulfan and High-Dose Cyclophosphamide Followed By Donor Bone Marrow Transplant in Treating Patients With Leukemia, Myelodysplastic Syndrome, Multiple Myeloma, or Recurrent Hodgkin or Non-Hodgkin Lymphoma

First Posted Date
2010-08-09
Last Posted Date
2010-08-09
Lead Sponsor
Case Comprehensive Cancer Center
Target Recruit Count
13
Registration Number
NCT01177371
Locations
🇺🇸

Ireland Cancer Center at University Hospitals Case Medical Center, Case Comprehensive Cancer Center, Cleveland, Ohio, United States

Combination Chemotherapy in Treating Young Adult Patients With Acute Lymphoblastic Leukemia

Not Applicable
Completed
Conditions
Leukemia
First Posted Date
2010-07-05
Last Posted Date
2021-09-13
Lead Sponsor
Gruppo Italiano Malattie EMatologiche dell'Adulto
Target Recruit Count
76
Registration Number
NCT01156883
Locations
🇮🇹

Azienda Ospedaliera - Nuovo Ospedale "Torrette", Ancona, Italy

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USL 8 - Ospedale S.Donato, Arezzo, Italy

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UO Ematologia con trapianto- AOU Policlinico Consorziale di Bari, Bari, Italy

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A Safety and Tolerability Study of Otelixizumab in Thyroid Eye Disease

First Posted Date
2010-05-03
Last Posted Date
2020-10-30
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
2
Registration Number
NCT01114503
Locations
🇬🇧

GSK Investigational Site, Newcastle upon Tyne, United Kingdom

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