Methylprednisolone hemisuccinate

Generic Name
Methylprednisolone hemisuccinate
Brand Names
Solu-medrol
Drug Type
Small Molecule
Chemical Formula
C26H34O8
CAS Number
2921-57-5
Unique Ingredient Identifier
5GMR90S4KN
Background

A water-soluble ester of methylprednisolone used for cardiac, allergic, and hypoxic emergencies.

Associated Conditions
Acute Gouty Arthritis, Ankylosing Spondylitis (AS), Berylliosis, Congenital Adrenal Hyperplasia (CAH), Congenital Hypoplastic Anemia, Dermatitis bullous, Dermatomyositis (DM), Edema of the cerebrum, Hypercalcemia of Malignancy, Immune Thrombocytopenia (ITP), Leukemias, Lymphoma, Multiple sclerosis exacerbation, Mycosis Fungoides (MF), Ophthalmia, Sympathetic, Pemphigus, Polymyositis, Primary adrenocortical insufficiency, Psoriatic Arthritis, Pure Red Cell Aplasia, Refractory Uveitis, Regional Enteritis, Rheumatoid Arthritis, Secondary adrenocortical insufficiency, Secondary thrombocytopenia, Stevens-Johnson Syndrome, Systemic Lupus Erythematosus, Temporal Arteritis, Trichinosis, Tuberculous Meningitis, Ulcerative Colitis, Acquired immune hemolytic anemia, Acute rheumatic carditis, Disseminated Pulmonary Tuberculosis (TB), Exfoliative erythroderma, Fulminating Pulmonary Tuberculosis, Idiopathic eosinophilic pneumonias, Non-suppurative Thyroiditis, Severe Allergic Reactions, Symptomatic Sarcoidosis
Associated Therapies
Palliative Treatment
Clinical Trials
Related News

Cytosine Arabinoside and Mitoxantrone for Patients With Juvenile Myelomonocytic Leukemia Receiving Repeat Stem Cell Transplantation

First Posted Date
2008-02-07
Last Posted Date
2017-12-28
Lead Sponsor
Masonic Cancer Center, University of Minnesota
Target Recruit Count
1
Registration Number
NCT00609739
Locations
🇺🇸

Masonic Cancer Center at University of Minnesota, Minneapolis, Minnesota, United States

Photopheresis for the Treatment of Acute Graft Versus Host Disease

First Posted Date
2008-02-07
Last Posted Date
2018-06-04
Lead Sponsor
M.D. Anderson Cancer Center
Target Recruit Count
81
Registration Number
NCT00609609
Locations
🇺🇸

University of Texas MD Anderson Cancer Center, Houston, Texas, United States

Treatment of Single or Double Umbilical Cord Trans + Graft-versus-host Disease (GVHD) Prophylaxis w/ Tacrolimus & Mycophenolate Mofetil

First Posted Date
2008-02-06
Last Posted Date
2014-05-20
Lead Sponsor
Vanderbilt-Ingram Cancer Center
Target Recruit Count
6
Registration Number
NCT00608517
Locations
🇺🇸

Vanderbilt-Ingram Cancer Center, Nashville, Tennessee, United States

🇺🇸

Veterans Affairs Medical Center - Nashville, Nashville, Tennessee, United States

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Vanderbilt-Ingram Cancer Center at Franklin, Nashville, Tennessee, United States

and more 1 locations

Trial of Rituximab for Graves' Ophthalmopathy

First Posted Date
2008-01-16
Last Posted Date
2016-01-01
Lead Sponsor
Rebecca Bahn
Target Recruit Count
25
Registration Number
NCT00595335
Locations
🇺🇸

Mayo Clinic, Rochester, Minnesota, United States

A Study of Rituximab (MabThera®/Rituxan®) in Patients With Rheumatoid Arthritis and Inadequate Response to Methotrexate

First Posted Date
2007-12-21
Last Posted Date
2015-04-10
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
185
Registration Number
NCT00578305

Steroids in Patients With Early ARDS

First Posted Date
2007-11-22
Last Posted Date
2007-11-22
Lead Sponsor
Catholic University of the Sacred Heart
Target Recruit Count
400
Registration Number
NCT00562835
Locations
🇮🇹

UCSC, Policlinico Universitario A. Gemelli, ICU, Rome, Italy

Evaluation of Tolerability and Efficacy of Erythropoietin (EPO) Treatment in Spinal Shock: Comparative Study Versus Methylprednisolone (MP)

First Posted Date
2007-11-20
Last Posted Date
2019-03-14
Lead Sponsor
Niguarda Hospital
Target Recruit Count
10
Registration Number
NCT00561067
Locations
🇮🇹

A.O. Ospedale Ca' Granda, Milan, Italy

Combination Chemotherapy With or Without Lestaurtinib in Treating Younger Patients With Newly Diagnosed Acute Lymphoblastic Leukemia

First Posted Date
2007-11-12
Last Posted Date
2024-07-15
Lead Sponsor
Children's Oncology Group
Target Recruit Count
218
Registration Number
NCT00557193
Locations
🇺🇸

Children's Hospital of Pittsburgh of UPMC, Pittsburgh, Pennsylvania, United States

🇺🇸

Connecticut Children's Medical Center, Hartford, Connecticut, United States

🇺🇸

MedStar Georgetown University Hospital, Washington, District of Columbia, United States

and more 167 locations

Donor Stem Cell Transplant in Treating Young Patients With Acute Myeloid Leukemia With Monosomy 7, -5/5q-, High FLT3-ITD AR, or Refractory or Relapsed Acute Myelogenous Leukemia

First Posted Date
2007-11-04
Last Posted Date
2020-04-16
Lead Sponsor
Children's Oncology Group
Target Recruit Count
158
Registration Number
NCT00553202
Locations
🇺🇸

AFLAC Cancer Center and Blood Disorders Service of Children's Healthcare of Atlanta - Egleston Campus, Atlanta, Georgia, United States

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Alvin and Lois Lapidus Cancer Institute at Sinai Hospital, Baltimore, Maryland, United States

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Nationwide Children's Hospital, Columbus, Ohio, United States

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A Study to Evaluate Two Doses of Ocrelizumab in Patients With Active Systemic Lupus Erythematosus (BEGIN)

First Posted Date
2007-10-05
Last Posted Date
2020-09-17
Lead Sponsor
Genentech, Inc.
Target Recruit Count
33
Registration Number
NCT00539838
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