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Zinc

Generic Name
Zinc
Brand Names
Vitafol-one, Wilzin
Drug Type
Small Molecule
Chemical Formula
Zn
CAS Number
7440-66-6
Unique Ingredient Identifier
J41CSQ7QDS
Background

A metallic element of atomic number 30 and atomic weight 65.38. It is a necessary trace element in the diet, forming an essential part of many enzymes, and playing an important role in protein synthesis and in cell division. Zinc deficiency is associated with anemia, short stature, hypogonadism, impaired wound healing, and geophagia. It is identified by the symbol Zn .

A newer study suggests implies that an imbalance of zinc is associated with the neuronal damage associated with traumatic brain injury, stroke, and seizures .

Understanding the mechanisms that control brain zinc homeostasis is, therefore, imperative to the development of preventive and treatment regimens for these and other neurological disorders .

In addition to the above, recent review articles have already demonstrated the important role of zinc in the pathophysiology and treatment of affective disorders, plus discussed the potential value of zinc as a marker of these diseases . Most recently, research has shown that polymorphism of the common polymorphism in zinc transporter SLC30A8/ZnT8 may increase susceptibility to type 2 diabetes provided novel insights into the role of zinc in diabetes .

Indication

Zinc can be used for the treatment and prevention of zinc deficiency/its consequences, including stunted growth and acute diarrhea in children, and slowed wound healing. It is also utilized for boosting the immune system, treating the common cold and recurrent ear infections, as well as preventing lower respiratory tract infections .

Associated Conditions
Candidiasis, Common Cold, Diaper Dermatitis, Diaper Rash, Eye redness, Iron Deficiency (ID), Ocular Irritation, Skin Irritation, Sunburn, Wilson's Disease, Zinc Deficiency
Associated Therapies
Dietary and Nutritional Therapies, Dietary supplementation

EMG-guided Botox Injection Versus Conventional Botox Injection in Gummy Smile Patients

Not Applicable
Not yet recruiting
Conditions
Excessive Gingival Display
Interventions
Procedure: Botox injection
Device: EMG
First Posted Date
2023-10-10
Last Posted Date
2023-10-10
Lead Sponsor
Cairo University
Target Recruit Count
32
Registration Number
NCT06075134

Effectiveness and Safety of Whitfield's Solution, Zinc Oxide Nanoparticles Solution or Combination for the Treatment of Fungal Feet Infection

Phase 4
Completed
Conditions
Fungal Foot Infection
Interventions
Drug: Whitfield solution
Drug: Combined Whitfield and Zinc oxide nanoparticles solution
First Posted Date
2023-06-13
Last Posted Date
2024-03-27
Lead Sponsor
Mahidol University
Target Recruit Count
84
Registration Number
NCT05901961
Locations
🇹🇭

Department of Dermatology Siriraj Hospital, Bangkoknoi, Bangkok, Thailand

Zinc Supplementation Prior to Botox Injections for Spasmodic Dysphonia

Phase 1
Active, not recruiting
Conditions
Spasmodic Dysphonia
Interventions
First Posted Date
2023-06-07
Last Posted Date
2025-02-25
Lead Sponsor
University of Florida
Target Recruit Count
36
Registration Number
NCT05892770
Locations
🇺🇸

University of Florida- Shands Hospital, Gainesville, Florida, United States

Singlet Oxygen Quantification After Skin Exposure to Ultraviolet A (UVA) Light

Not Applicable
Completed
Conditions
Sun Damaged Skin
Interventions
First Posted Date
2023-05-18
Last Posted Date
2025-04-27
Lead Sponsor
University of California, Davis
Target Recruit Count
17
Registration Number
NCT05865431
Locations
🇺🇸

University of California, Davis, Sacramento, California, United States

Effect of Zinc on Glucose Homeostasis

Phase 4
Recruiting
Conditions
Prediabetic State
Hyperglycemia
Interventions
First Posted Date
2023-04-28
Last Posted Date
2025-04-23
Lead Sponsor
University of Maryland, Baltimore
Target Recruit Count
200
Registration Number
NCT05835037
Locations
🇺🇸

Amish Research Clinic, Lancaster, Pennsylvania, United States

Study to Evaluate the Possible Antifibrotic Effect of Zinc Sulphate in Chronic HCV Patient Receiving Direct Acting Anti-viral Therapy.

Phase 3
Completed
Conditions
Hepatitis C
Interventions
First Posted Date
2022-07-19
Last Posted Date
2023-10-17
Lead Sponsor
Tanta University
Target Recruit Count
50
Registration Number
NCT05465434
Locations
🇪🇬

National Liver Institute, Shibīn Al Kawm, Egypt

Zinc Containing Vaginal Topical " Suppository "

Phase 1
Completed
Conditions
Genitourinary Syndrome of Menopause
Interventions
First Posted Date
2022-07-12
Last Posted Date
2023-10-17
Lead Sponsor
Egymedicalpedia
Target Recruit Count
50
Registration Number
NCT05453227
Locations
🇪🇬

Al-Azhar University Hospitals and Ashmoun central hospital, Cairo, Elmenofia, Egypt

Zincoxide-propolis vs Zincoxide-eugenol Pulpectomy

Early Phase 1
Conditions
Pulp Necroses
Interventions
First Posted Date
2022-02-09
Last Posted Date
2022-02-09
Lead Sponsor
Cairo University
Target Recruit Count
38
Registration Number
NCT05230797

Effectiveness of Zinc Supplementation in Management of Patients With Symptomatic Benign Migratory Glossitis

Phase 4
Completed
Conditions
Benign Migratory Glossitis
Interventions
First Posted Date
2022-01-13
Last Posted Date
2023-08-01
Lead Sponsor
mariam hamouda
Target Recruit Count
48
Registration Number
NCT05190562
Locations
🇪🇬

Ain Shams University, Cairo, Egypt

The Therapeutic Effect of Co-administration of Pentoxifylline and Zinc in Men With Idiopathic Asthenozoospermia

Early Phase 1
Conditions
Men Infertility
Interventions
First Posted Date
2022-01-05
Last Posted Date
2022-01-05
Lead Sponsor
Arak University of Medical Sciences
Target Recruit Count
160
Registration Number
NCT05178953
Locations
🇮🇷

Arak university of medical science, Arak, Markazi, Iran, Islamic Republic of

🇮🇷

Infertility Center, Arak, Markazi, Iran, Islamic Republic of

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