Hydromorphone
- Generic Name
- Hydromorphone
- Brand Names
- Dilaudid, Exalgo, Hydromorph Contin, Hydromorphone Hp Forte
- Drug Type
- Small Molecule
- Chemical Formula
- C17H19NO3
- CAS Number
- 466-99-9
- Unique Ingredient Identifier
- Q812464R06
- Background
Hydromorphone is a pure opioid, a semi-synthetic hydrogenated ketone derivative of morphine that has been available clinically since 1920. Structurally, hydromorphone derived from morphine in the modification of the hydroxyl group in the carbon 6 to a carbonyl and the absence of a double bond between the carbon 7 and 8. Due to these modifications, it present...
- Indication
Hydromorphone is indicated for the management of moderate to severe acute pain and severe chronic pain. Due to its addictive potential and overdose risk, hydromorphone is only prescribed when other first-line treatments have failed.
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- Associated Conditions
- Neuropathic Pain, Refractory Chronic Cough, Moderate to severe pain
- Associated Therapies
- -
Comparing Individualized vs. Weight Based Protocols to Treat Vaso-Occlusive Episodes in Sickle Cell Disease
- Conditions
- Interventions
- First Posted Date
- 2019-05-01
- Last Posted Date
- 2023-07-03
- Lead Sponsor
- Duke University
- Target Recruit Count
- 328
- Registration Number
- NCT03933397
- Locations
- 🇺🇸
University of Texas Southwestern Medical Center, Dallas, Texas, United States
🇺🇸University of Maryland, Baltimore, Maryland, United States
🇺🇸Henry Ford Health System, Detroit, Michigan, United States
Effect of Methadone and Hydromorphone on the QT Interval After Anesthesia and Surgery
- First Posted Date
- 2019-03-28
- Last Posted Date
- 2019-09-13
- Lead Sponsor
- NorthShore University HealthSystem
- Target Recruit Count
- 140
- Registration Number
- NCT03893734
- Locations
- 🇺🇸
NorthShore University HealthSystem, Evanston, Illinois, United States
Study in Subjects Undergoing Complete Abdominoplasty
- First Posted Date
- 2018-12-28
- Last Posted Date
- 2024-03-19
- Lead Sponsor
- Concentric Analgesics
- Target Recruit Count
- 54
- Registration Number
- NCT03789318
- Locations
- 🇺🇸
Lotus Clinical Research, LLC, Pasadena, California, United States
Non-Steroidal or Opioid Analgesia Use for Children With Musculoskeletal Injuries
- Conditions
- Interventions
- First Posted Date
- 2018-12-07
- Last Posted Date
- 2023-04-10
- Lead Sponsor
- University of Alberta
- Target Recruit Count
- 710
- Registration Number
- NCT03767933
- Locations
- 🇨🇦
Children's Hospital of Winnipeg, Winnipeg, Manitoba, Canada
🇨🇦Stollery Children's Hospital Emergency Department, Edmonton, Alberta, Canada
🇨🇦Alberta Children's Hospital, Calgary, Alberta, Canada
Optimizing Outpatient Anesthesia (OSPREy-Outpatient Surgery Pain Relief Enhancement)
- Conditions
- Interventions
- First Posted Date
- 2018-10-31
- Last Posted Date
- 2024-02-02
- Lead Sponsor
- Duke University
- Target Recruit Count
- 907
- Registration Number
- NCT03726268
- Locations
- 🇺🇸
Duke University Medical Center, Durham, North Carolina, United States
Postoperative Analgesic Effect of Hydromorphone on Partial Pulmonary Resection Under Video-assisted Thoracoscopy
- Conditions
- Interventions
- First Posted Date
- 2018-08-27
- Last Posted Date
- 2018-09-26
- Target Recruit Count
- 171
- Registration Number
- NCT03648008
- Locations
- 🇨🇳
The second affiliated hospital of Zhejiang University, Hangzhou, Zhejiang, China
Levorphanol as a Second Line Opioid in Reducing Pain in Patients With Cancer
- First Posted Date
- 2018-07-06
- Last Posted Date
- 2024-06-18
- Lead Sponsor
- M.D. Anderson Cancer Center
- Target Recruit Count
- 43
- Registration Number
- NCT03579446
- Locations
- 🇺🇸
M D Anderson Cancer Center, Houston, Texas, United States
IV Acetaminophen as Adjuvant Analgesic to Hydromorphone - Emergency Department Patients
- Conditions
- Interventions
- First Posted Date
- 2018-06-12
- Last Posted Date
- 2022-03-02
- Lead Sponsor
- Albert Einstein College of Medicine
- Target Recruit Count
- 162
- Registration Number
- NCT03553498
- Locations
- 🇺🇸
Montefiore Medical Center, Bronx, New York, United States
Opioid Analgesics for Acute Fracture Pain in Adults Discharged From the ED
- Conditions
- Interventions
- First Posted Date
- 2018-03-27
- Last Posted Date
- 2019-10-02
- Lead Sponsor
- Mount Sinai Hospital, Canada
- Target Recruit Count
- 5
- Registration Number
- NCT03478423
- Locations
- 🇨🇦
Mount Sinai Hospital, Toronto, Ontario, Canada
Anesthetics and Analgesics in Children
- Conditions
- Interventions
- First Posted Date
- 2018-02-09
- Last Posted Date
- 2024-01-18
- Lead Sponsor
- Kanecia Obie Zimmerman
- Target Recruit Count
- 460
- Registration Number
- NCT03427736
- Locations
- 🇺🇸
Baylor College of Medicine, Houston, Texas, United States
🇺🇸Ann and Robert H. Lurie Childrens Hospital of Chicago, Chicago, Illinois, United States
🇺🇸Washington University School of Medicine, Saint Louis, Missouri, United States
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.