Triamcinolone

Generic Name: Triamcinolone

Brand Names: Allernaze, Aristocort, Aristocort R, Juulissa Pharmapak, Kenalog, Kourzeq, Marcaine, Nasacort, Oracort, Oralone, Pediaderm Ta, Triaderm, Trianex, Triderm, Triesence, Triloan Suik, Tritocin, Viaderm Kc, Xipere, Zilretta

Drug Type: Small Molecule

Chemical Formula: C_₂₁H_₂₇FO_₆

CAS Number: 124-94-7

Unique Ingredient Identifier: 1ZK20VI6TY

Background: Triamcinolone is a corticosteroid used to treat various inflammatory conditions in the body from allergic rhinitis to acute exacerbations of multiple sclerosis. Triamcinolone can be used as a one time adjunct treatment of osteoarthritic knee pain, or first line as a topical treatment of corticosteroid responsive dermatoses. Triamcinolone is more commonly seen in the forms triamcinolone hexacetonide, triamcinolone acetonide, and triamcinolone diacetate.

Triamcinolone was granted FDA approval on 3 December 1957. In October 2021, a suspension of triamcinolone acetonide was approved for suprachoroidal injection - the first suprachoroidal injection to receive FDA approval - for the treatment of patients with macular edema associated with uveitis.

Indication: 肾上腺皮质激素类药。主要用于过敏性与自身免疫性炎症性疾病。由于本品潴钠作用较弱，故一般不用作肾上腺皮质功能减退的替代治疗。

Associated Conditions: Acne, Acne Vulgaris, Acute Gouty Arthritis, Allergic Contact Dermatitis, Allergic Rhinitis (AR), Allergic Skin Reaction, Alopecia Areata (AA), Ankylosing Spondylitis (AS), Aphthous Stomatitis, Asthma, Atopic Dermatitis, Autoimmune Hemolytic Anemia, Berylliosis, Bullous dermatitis herpetiformis, Chronic Eczema, Chronic Inflammatory Skin Diseases, Congenital Adrenal Hyperplasia (CAH), Congenital Hypoplastic Anemia, Contact Dermatitis, Crohn's Disease (CD), Dental Cavity, Dermatitis, Dermatomyositis (DM), Diaper Rash, Discoid Lupus Erythematosus (DLE), Edema of the cerebrum, Epicondylitis, Erythroderma, Fungal Infections, Fungal infectious disorders of the Beard, Fungal skin infection, Gingivitis, Haemorrhoids, Hemangiomas, Hypercalcemia, Inflammation of Mouth, Intertrigo, Itching of the Anus, Itching of the External Genitalia, Itching of the Foot, Itching of the genitals, Itching of the hand, Juvenile Idiopathic Arthritis (JIA), Keloids Scars, Leukemias, Lichen Planus (LP), Lichen simplex chronicus, Lymphoma, Macular Edema, Mycosis Fungoides (MF), Mycotic Eczema, Necrobiosis lipoidica diabeticorum, Neurodermatitis, Nummular Dermatitis, Ocular Inflammation, Ophthalmia, Sympathetic, Oral Erosive Lichen Planus, Otitis Externa, Pemphigus, Pericarditis, Polymyositis, Postherpetic Neuralgia, Primary adrenocortical insufficiency, Proteinuria, Psoriasis Vulgaris (Plaque Psoriasis), Psoriatic Arthritis, Psoriatic plaque, Pure Red Cell Aplasia, Purulent Wounds, Pyoderma caused by susceptible bacteria, Regional Enteritis, Rheumatoid Arthritis, Ringworm Folliculitis, Seborrheic Dermatitis, Seborrheic Dermatitis, Eczematous, Secondary Impetiginization, Secondary adrenocortical insufficiency, Secondary thrombocytopenia, Serum Sickness, Skin chapped, Stomatitis, Denture, Synovitis, Systemic Lupus Erythematosus, Temporal Arteritis, Tinea Corporis, Transfusion Reactions, Trichinosis, Tuberculosis (TB), Ulcerative Colitis, Urticaria, Uveitis, Wound Infections, Acute Bursitis, Acute Multiple sclerosis, Acute Rheumatic heart disease, unspecified, Acute Tenosynovitis, Corticosteroid-responsive dermatoses, Cutaneous candidiasis, Cystic tumour of the ganglia, Exfoliative erythroderma, Granuloma annulare lesions, Idiopathic eosinophilic pneumonias, Non-suppurative Thyroiditis, Oral infections, Oral lesions, Severe Erythema multiforme, Subacute Dermatitis, Eczematous, Symptomatic Sarcoidosis, Ulceration of the mouth, Ulcerative stomatitis

Associated Therapies: -

Clinical Trials

Hydros and Hydros-TA Joint Therapy for Pain Associated With Knee Osteoarthritis

Phase 3

Completed

Conditions: Osteoarthritis of the Knee

Interventions: Device: Hydros
Device: Hydros-TA
Drug: Triamcinolone Acetonide

First Posted Date: 2013-12-30

Last Posted Date: 2016-08-25

Lead Sponsor: Carbylan Therapeutics, Inc.

Target Recruit Count: 510

Registration Number: NCT02022930

Postoperative Pain Control Following Vitreoretinal Surgery

Phase 4

Completed

Conditions: Retinal Detachment
Proliferative Vitreoretinopathy
Retinoschisis

Interventions: Drug: Triamcinolone
Drug: Bupivicaine Hydrochloride

First Posted Date: 2013-11-26

Last Posted Date: 2017-03-21

Lead Sponsor: Emory University

Target Recruit Count: 58

Registration Number: NCT01995045

Locations: 🇺🇸
Emory University Eye Center, Atlanta, Georgia, United States

Study to Evaluate Fractional Collagen Synthesis Within Keloid Scars and Identify Biomarkers of Keloid Scars

Phase 1

Terminated

Conditions: Fibrosis

Interventions: Drug: Placebo
Drug: Triamcinolone acetonide

First Posted Date: 2013-11-07

Last Posted Date: 2017-05-15

Lead Sponsor: GlaxoSmithKline

Target Recruit Count: 9

Registration Number: NCT01978301

Locations: 🇬🇧
GSK Investigational Site, London, United Kingdom

A Comparison Between Sonoguided Injection Corticosteroid and Hyaluronic Acid Injection in Treatment of Trigger Finger

Not Applicable

Completed

Conditions: Trigger Finger

Interventions: Drug: triamcinolone acetonide
Drug: Hyaluronic Acid

First Posted Date: 2013-09-25

Last Posted Date: 2014-11-04

Lead Sponsor: Taipei Veterans General Hospital, Taiwan

Target Recruit Count: 36

Registration Number: NCT01950793

Locations: 🇨🇳
Taipei Veterans General Hospital, Taipei, Taiwan

Ultrasound Guided Transversus Abdominis Plane (TAP) vs. Trigger Point Injection (TPI) for Abdominal Wall Pain

Phase 2

Completed

Conditions: Abdominal Pain

Interventions: Drug: Bupivacaine 0.25%
Drug: Triamcinolone

First Posted Date: 2013-07-24

Last Posted Date: 2020-05-14

Lead Sponsor: Mayo Clinic

Target Recruit Count: 62

Registration Number: NCT01906944

Locations: 🇺🇸
Mayo Clinic in Rochester, Rochester, Minnesota, United States

Cataract Surgery With Intracameral Triamcinolone in Infants

Not Applicable

Completed

Conditions: Cataract

Interventions: Drug: Triamcinolone acetonide
Drug: Prednisolone syrup

First Posted Date: 2013-02-28

Last Posted Date: 2013-08-14

Lead Sponsor: Fundação Altino Ventura

Target Recruit Count: 60

Registration Number: NCT01800708

Locations: 🇧🇷
Altino Ventura Foundation, Recife, Pernambuco, Brazil

PRevention of Macular EDema After Cataract Surgery

Phase 3

Completed

Conditions: Cystoid Macular Edema
Diabetes Mellitus
Cataract

Interventions: Drug: Bromfenac
Drug: Dexamethasone
Drug: Triamcinolone Acetonide
Drug: Bevacizumab

First Posted Date: 2013-01-24

Last Posted Date: 2017-04-14

Lead Sponsor: Maastricht University Medical Center

Target Recruit Count: 1127

Registration Number: NCT01774474

Locations: 🇦🇹
Hospital of the Brothers of Saint John of God, Vienna, Austria
🇧🇪
University Hospital Antwerp, Edegem, Belgium
🇳🇱
Academic Medical Center, Amsterdam, Netherlands

and more 13 locations