Minocycline
- Generic Name
- Minocycline
- Brand Names
- Amzeeq, Arestin, Dynacin, Minocin, Minolira, Solodyn, Ximino, Zilxi
- Drug Type
- Small Molecule
- Chemical Formula
- C23H27N3O7
- CAS Number
- 10118-90-8
- Unique Ingredient Identifier
- FYY3R43WGO
- Background
Minocycline was first described in the literacture in 1966. It is a second generation tetracycline antibiotic that is active against gram-negative and gram-positive bacteria. Like other semisynthetic tetracyclines, minocycline has modifications to carbons 7-9 on the D ring to generate higher efficacy than previous tetracyclines.
...
- Indication
Oral and topical minocycline are indicated to treat inflammatory lesions of acne vulgaris. Subgingival microspheres are indicated as an adjunct treatment in the reduction of pocket depth in adults with periodontitis. Oral and intravenous formulations are indicated to treat infections of susceptible microorganisms. These include rickettsiae, Mycoplasma pneumo...
- Associated Conditions
- Bartonellosis, Brucellosis, Campylobacter fetus, Chancroid, Cholera (Disorder), Conjunctivitis, Inclusion, Granuloma Inguinale, Lymphogranuloma Venereum, Nongonococcal urethritis, Periodontitis, Plague, Psittacosis, Q Fever, Relapsing Fever, Respiratory Tract Infections (RTI), Rickettsia Infections, Rickettsialpox, Rocky Mountain Spotted Fever, Trachoma, Tularemia, Typhus infections, Inflammatory lesions
- Associated Therapies
- -
Systemic and Topical Treatments for Rash Secondary to Erlotinib in Lung Cancer
- Conditions
- Interventions
- First Posted Date
- 2007-05-14
- Last Posted Date
- 2017-04-04
- Lead Sponsor
- British Columbia Cancer Agency
- Target Recruit Count
- 150
- Registration Number
- NCT00473083
- Locations
- 🇨🇦
Tom Baker Cancer Centre, Calgary, Alberta, Canada
🇨🇦Cross Cancer Institute, Edmonton, Alberta, Canada
🇨🇦BC Cancer Agency Vancouver Centre, Vancouver, British Columbia, Canada
Evaluation of the Utility of Minocycline as an Anti-Inflammatory Agent in the Treatment of Asthma
- First Posted Date
- 2007-04-05
- Last Posted Date
- 2017-04-18
- Target Recruit Count
- 20
- Registration Number
- NCT00456677
- Locations
- 🇺🇸
SUNY Downstate Medical Center, Brooklyn, New York, United States
Minocycline to Treat Childhood Regressive Autism
- First Posted Date
- 2006-12-11
- Last Posted Date
- 2015-12-11
- Lead Sponsor
- National Institute of Mental Health (NIMH)
- Target Recruit Count
- 11
- Registration Number
- NCT00409747
- Locations
- 🇺🇸
Childrens National Medical Center, Washington, District of Columbia, United States
🇺🇸National Institutes of Health Clinical Center, 9000 Rockville Pike, Bethesda, Maryland, United States
A Study of the Effects of Minocycline on Cognitive Function After Carotid Endarterectomy
- First Posted Date
- 2006-11-22
- Last Posted Date
- 2017-07-14
- Lead Sponsor
- Brigham and Women's Hospital
- Registration Number
- NCT00401921
- Locations
- 🇺🇸
Brigham and Women's Hospital, Boston, Massachusetts, United States
Minocycline for the Treatment of Decreased Mental Function in HIV-Infected Adults
- First Posted Date
- 2006-08-08
- Last Posted Date
- 2016-02-05
- Target Recruit Count
- 107
- Registration Number
- NCT00361257
- Locations
- 🇺🇸
Univ of Washington, Harborview Medical Ctr, Seattle, Washington, United States
🇺🇸1101 University of Rochester Medical Center, Division of Infectious Diseases, Rochester, New York, United States
🇺🇸UCLA-David Geffen School of Medicine, Los Angeles, California, United States
Combination Therapy Selection Trial in Amyotrophic Lateral Sclerosis
- Conditions
- Interventions
- First Posted Date
- 2006-07-24
- Last Posted Date
- 2011-02-01
- Lead Sponsor
- Columbia University
- Target Recruit Count
- 86
- Registration Number
- NCT00355576
- Locations
- 🇺🇸
UT Southwestern Medical Center, Dallas, Texas, United States
🇺🇸UMDNJ, New Brunswick, New Jersey, United States
🇺🇸University of Pennsylvania, Philadelphia, Pennsylvania, United States
Pilot Study of Minocycline in Huntington's Disease
- First Posted Date
- 2006-01-16
- Last Posted Date
- 2013-04-19
- Lead Sponsor
- Merit Cudkowicz
- Target Recruit Count
- 114
- Registration Number
- NCT00277355
- Locations
- 🇺🇸
Washington University School of Medicine, St. Louis, Missouri, United States
🇺🇸University of Alabama at Birmingham, Birmingham, Alabama, United States
🇺🇸University of South Florida, Tampa, Florida, United States
Tetracycline-Derivatives for Treatment of Cerebral Arteriovenous Malformations and Aneurysms
- Conditions
- Interventions
- First Posted Date
- 2005-10-25
- Last Posted Date
- 2013-10-09
- Lead Sponsor
- University of California, San Francisco
- Target Recruit Count
- 26
- Registration Number
- NCT00243893
- Locations
- 🇺🇸
University of California, San Francisco, California, United States
Study Comparing Acne in Patients Taking Oral Minocycline to Patients Taking Minocycline Plus Topical Tretinoin
- Conditions
- Interventions
- First Posted Date
- 2005-10-18
- Last Posted Date
- 2012-02-24
- Lead Sponsor
- Derm Research @ 888 Inc.
- Target Recruit Count
- 38
- Registration Number
- NCT00240513
- Locations
- 🇨🇦
Derm Research @ 888 Inc, Vancouver, British Columbia, Canada
Minocycline Therapy for Lung Scarring in Patients With Idiopathic Pulmonary Fibrosis - a Pilot Study
- Conditions
- First Posted Date
- 2005-09-20
- Last Posted Date
- 2006-09-11
- Lead Sponsor
- University of California, Los Angeles
- Registration Number
- NCT00203697
- Locations
- 🇺🇸
UCLA Pulmonary Outpatient Clinic, Los Angeles, California, United States
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.