Sertraline
- Generic Name
- Sertraline
- Brand Names
- Zoloft
- Drug Type
- Small Molecule
- Chemical Formula
- C17H17Cl2N
- CAS Number
- 79617-96-2
- Unique Ingredient Identifier
- QUC7NX6WMB
- Background
Sertraline is a popular antidepressant medication commonly known as a selective serotonin reuptake inhibitor (SSRI), and is similar to drugs such as Citalopram and Fluoxetine. Despite marked structural differences between compounds in this drug class, SSRIs exert similar pharmacological effects.
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- Indication
Sertraline is indicated for the management of major depressive disorder (MDD), post-traumatic stress disorder (PTSD), obsessive-compulsive disorder (OCD), panic disorder (PD), premenstrual dysphoric disorder (PMDD), and social anxiety disorder (SAD). Common off-label uses for sertraline include the prevention of post stroke depression, generalized anxiety di...
- Associated Conditions
- Binge Eating Disorder (BED), Bulimia Nervosa, Generalized Anxiety Disorder, Major Depressive Disorder (MDD), Obsessive Compulsive Disorder (OCD), Panic Disorder, Post Traumatic Stress Disorder (PTSD), Premenstrual Dysphoric Disorder (PMDD), Social Anxiety Disorder (SAD)
- Associated Therapies
- -
Effect of Brain Lesion Severity on Treatment Response in Late-Life Depression
- Conditions
- First Posted Date
- 2006-06-20
- Last Posted Date
- 2013-08-09
- Lead Sponsor
- Duke University
- Target Recruit Count
- 131
- Registration Number
- NCT00339066
- Locations
- 🇺🇸
Duke University Medical Center, Durham, North Carolina, United States
🇺🇸Washington University in St. Louis, St. Louis, Missouri, United States
Short-Term Versus Long-Term Treatment for Severe Premenstrual Syndrome (PMS)
- Conditions
- First Posted Date
- 2006-04-27
- Last Posted Date
- 2009-02-27
- Target Recruit Count
- 174
- Registration Number
- NCT00318773
- Locations
- 🇺🇸
Department of Obstetrics/Gynecology, University of Pennsylvania, School of Medicine, Philadelphia, Pennsylvania, United States
Exercise to Treat Depression in Individuals With Coronary Heart Disease
- Conditions
- Interventions
- First Posted Date
- 2006-03-13
- Last Posted Date
- 2015-06-29
- Lead Sponsor
- Duke University
- Target Recruit Count
- 101
- Registration Number
- NCT00302068
- Locations
- 🇺🇸
Duke University Medical Center, Durham, North Carolina, United States
Augmentation Study of Levetiracetam in Obsessive Compulsive Disorder
- Conditions
- Interventions
- First Posted Date
- 2006-03-07
- Last Posted Date
- 2013-04-11
- Lead Sponsor
- Duke University
- Target Recruit Count
- 12
- Registration Number
- NCT00299611
- Locations
- 🇺🇸
Duke University Medical Center, Durham, North Carolina, United States
Flushes and Sertraline Trial
- Conditions
- First Posted Date
- 2006-01-27
- Last Posted Date
- 2006-08-04
- Lead Sponsor
- University of California, San Francisco
- Target Recruit Count
- 100
- Registration Number
- NCT00283192
- Locations
- 🇺🇸
UCSF Women's Health Clinical Research Center, San Francisco, California, United States
Improving Treatment Outcomes in Pharmacotherapy of Generalized Social Anxiety Disorder
- Conditions
- Interventions
- First Posted Date
- 2006-01-27
- Last Posted Date
- 2013-10-14
- Lead Sponsor
- Massachusetts General Hospital
- Target Recruit Count
- 397
- Registration Number
- NCT00282828
- Locations
- 🇺🇸
University of California San Diego, La Jolla, California, United States
🇨🇦McMaster University Medical Centre Anxiety Disorders Clinic, Hamilton, Ontario, Canada
🇺🇸Center for Anxiety and Traumatic Stress Disorders, Boston, Massachusetts, United States
Sertraline for the Prevention of Recurrent Postpartum Depression
- Conditions
- First Posted Date
- 2006-01-13
- Last Posted Date
- 2013-10-07
- Lead Sponsor
- University of Pittsburgh
- Target Recruit Count
- 300
- Registration Number
- NCT00276900
- Locations
- 🇺🇸
Women's Behavioral HealthCare Program, Pittsburgh, Pennsylvania, United States
Bipolar II Depression: Lithium, SSRI, or the Combination
- Conditions
- Interventions
- First Posted Date
- 2006-01-13
- Last Posted Date
- 2013-05-10
- Lead Sponsor
- Lindner Center of HOPE
- Target Recruit Count
- 139
- Registration Number
- NCT00276965
- Locations
- 🇺🇸
UCLA, Los Angeles, California, United States
🇺🇸Stanford University - Bipolar Research Program, Palo Alto, California, United States
🇺🇸Lindner Center of HOPE, affliated with University of Cincinnati Medical Center, Mason, Ohio, United States
A Research Study to Compare the Treatments of a Combination of Elzasonan With Zoloft, to Zoloft Alone, or Placebo in People With Major Depressive Disorder (MDD)
- Conditions
- First Posted Date
- 2006-01-11
- Last Posted Date
- 2008-11-02
- Lead Sponsor
- Pfizer
- Target Recruit Count
- 262
- Registration Number
- NCT00275197
- Locations
- 🇷🇺
Pfizer Investigational Site, St. Petersburg, Russian Federation
Modulation of Visually Evoked Potentials by an Antidepressant
- Conditions
- First Posted Date
- 2005-12-07
- Last Posted Date
- 2007-06-04
- Lead Sponsor
- University Hospital Freiburg
- Target Recruit Count
- 12
- Registration Number
- NCT00263133
- Locations
- 🇩🇪
Dept. of Psychiatry, University of Freiburg, Freiburg, Germany
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.