Ceftriaxone
- Generic Name
- Ceftriaxone
- Brand Names
- Rocephin
- Drug Type
- Small Molecule
- Chemical Formula
- C18H18N8O7S3
- CAS Number
- 73384-59-5
- Unique Ingredient Identifier
- 75J73V1629
- Background
Ceftriaxone is a broad-spectrum third-generation cephalosporin antibiotic. It has a very long half-life compared to other cephalosporins and is high penetrable into the meninges, eyes, and inner ear. Ceftriaxone has broader and stronger gram-negative coverage then first or second-generation cephalosporins, but worse activity against methicillin-susceptible S...
- Indication
Ceftriaxone is used for the treatment of the infections (respiratory, skin, soft tissue, UTI, ENT) caused by susceptible organisms. Organisms that are generally susceptible to ceftriaxone include S. pneumoniae, S. pyogenes (group A beta-hemolytic streptococci), coagulase-negative staphylococci, Some Enterobacter spp, H. influenzae, N. gonorrhoeae, P. mirabil...
- Associated Conditions
- Abscess Brain, Bacterial Endocarditis, Bacterial Infections, Bacterial Sinusitis, Bone and Joint Infections, Chancroid, Community Acquired Pneumonia (CAP), Conjunctivitis gonococcal neonatal, Epididymitis, Epiglottitis, Gonococcal arthritis, Gonococcal infection of pharynx, Gonococcal pelvic inflammatory disease, Intraabdominal Infections, Lower respiratory tract infection bacterial, Lyme Neuroborreliosis, Meningitis, Bacterial, Ophthalmia neonatorum due to gonococcus, Postoperative Infections, Prosthetic Joint Infections, Sepsis Bacterial, Septic Arthritis, Shigellosis, Skin and Subcutaneous Tissue Bacterial Infections, Syphilis, Vulvovaginitis gonococcal, Whipple Disease, Bacterial otitis media, Complicated Urinary Tract Infection caused by susceptible bacteria, Disease caused by Salmonella typhi, Susceptible Bacterial Infections, Uncomplicated Gonorrhea, Uncomplicated Urinary tract infection bacterial
- Associated Therapies
- -
Pharmacokinetic of Ceftriaxone in Septic ICU Patients
- Conditions
- First Posted Date
- 2007-03-21
- Last Posted Date
- 2007-03-21
- Target Recruit Count
- 70
- Registration Number
- NCT00449800
- Locations
- 🇫🇷
Cenrte Hospitalier Régional Universitaire, Tours, France
Ceftriaxone Vs Levofloxacin on Cytokine Expression in Pneumococcal Pneumonia
- Conditions
- First Posted Date
- 2007-02-01
- Last Posted Date
- 2007-02-01
- Lead Sponsor
- Hospital Mutua de Terrassa
- Target Recruit Count
- 45
- Registration Number
- NCT00429975
- Locations
- 🇪🇸
Hospital Mutua de Terrassa, Terrassa, Barcelona, Spain
Prevention of Pneumonia Comparing Ceftriaxone With Subglottic Aspiration
- Conditions
- First Posted Date
- 2006-09-12
- Last Posted Date
- 2006-09-26
- Lead Sponsor
- Hospital Universitario Principe de Asturias
- Target Recruit Count
- 80
- Registration Number
- NCT00374959
- Locations
- 🇪🇸
Enrique Cerda Cerda, Getafe, Madrid, Spain
🇪🇸Francisco Alvarez Lerma, Barcelona, Spain
🇪🇸Miguel Sanchez Garcia, Alcala de Henares, Madrid, Spain
Ceftriaxone Versus Chloramphenicol for Treatment of Severe Pneumonia in Children
- Conditions
- First Posted Date
- 2006-09-07
- Last Posted Date
- 2010-07-26
- Lead Sponsor
- Makerere University
- Target Recruit Count
- 348
- Registration Number
- NCT00372541
- Locations
- 🇺🇬
Department of paediatrics and child Health,Makerere university, Kampala, Uganda
🇺🇬Department of Paediatrics and Child Health, Mulago Hospital, Kampala, East Africa, Uganda
🇺🇬Department of Paediatrics and Child Health, Makerere University, Kampala, Uganda
Cefepime vs. Ceftriaxone to Treat Nursing Home-Acquired Pneumonia
- First Posted Date
- 2006-07-31
- Last Posted Date
- 2007-10-31
- Lead Sponsor
- CPL Associates
- Target Recruit Count
- 69
- Registration Number
- NCT00358202
- Locations
- 🇺🇸
CPL Associates,LLC, Buffalo, New York, United States
Clinical Trial Ceftriaxone in Subjects With ALS
- Conditions
- Interventions
- First Posted Date
- 2006-07-07
- Last Posted Date
- 2014-04-21
- Lead Sponsor
- Massachusetts General Hospital
- Target Recruit Count
- 513
- Registration Number
- NCT00349622
- Locations
- 🇺🇸
University of Pennsylvania, Philadelphia, Pennsylvania, United States
🇺🇸University of Pittsburgh, Pittsburgh, Pennsylvania, United States
🇺🇸Lahey Clinic, Burlington, Massachusetts, United States
Effect of Intravenous Ceftriaxone and Oral Doxycycline for Lyme Neuroborreliosis
- First Posted Date
- 2005-08-30
- Last Posted Date
- 2023-05-06
- Lead Sponsor
- Sorlandet Hospital HF
- Target Recruit Count
- 120
- Registration Number
- NCT00138801
- Locations
- 🇳🇴
Sørlandet Sykehus HF, Kristiansand, Vest-Agder, Norway
A Study to Assess Beta-Lactam in the Treatment of Hospitalized Patients With Bacterial Pneumonia
- First Posted Date
- 2005-05-25
- Last Posted Date
- 2016-11-02
- Lead Sponsor
- Hoffmann-La Roche
- Target Recruit Count
- 302
- Registration Number
- NCT00111644
VNP20009 in Treating Patients With Advanced or Metastatic Solid Tumors That Have Not Responded to Previous Therapy
- Conditions
- First Posted Date
- 2004-02-25
- Last Posted Date
- 2013-07-18
- Lead Sponsor
- Vion Pharmaceuticals
- Registration Number
- NCT00004216
- Locations
- 🇺🇸
Mary Crowley Medical Research Center, Dallas, Texas, United States
🇺🇸Cleveland Clinic Taussig Cancer Center, Cleveland, Ohio, United States
🇺🇸Beth Israel Deaconess Medical Center, Boston, Massachusetts, United States
Brain Imaging and Retreatment Study of Persistent Lyme Disease
- Conditions
- First Posted Date
- 2002-05-20
- Last Posted Date
- 2005-12-07
- Target Recruit Count
- 65
- Registration Number
- NCT00037479
- Locations
- 🇺🇸
Columbia Presbyterian Medical Center, New York, New York, United States
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.