Gabapentin
- Generic Name
- Gabapentin
- Brand Names
- Gralise, Neurontin
- Drug Type
- Small Molecule
- Chemical Formula
- C9H17NO2
- CAS Number
- 60142-96-3
- Unique Ingredient Identifier
- 6CW7F3G59X
- Background
Gabapentin is a structural analogue of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA) that was first approved for use in the United States in 1993. It was originally developed as a novel anti-epileptic for the treatment of certain types of seizures - today it is also widely used to treat neuropathic pain. Gabapentin has some stark advantages ...
- Indication
In the United States, gabapentin is officially indicated for the treatment of postherpetic neuralgia in adults and for the adjunctive treatment of partial-onset seizures, with or without secondary generalization, in patients 3 years of age and older. In Europe, gabapentin is indicated for adjunctive therapy in the treatment of partial-onset seizures, with or...
- Associated Conditions
- Partial-Onset Seizures, Peripheral Neuropathic Pain, Postherpetic Neuralgia
- Associated Therapies
- -
Fexofenadine Versus Gabapentin for Uremic Pruritus in Patients on Regular Hemodialysis
- Conditions
- Interventions
- First Posted Date
- 2024-06-20
- Last Posted Date
- 2024-11-19
- Lead Sponsor
- Tanta University
- Target Recruit Count
- 60
- Registration Number
- NCT06466421
- Locations
- 🇪🇬
Tanta University, Tanta, Elgharbia, Egypt
Impact of Preoperative Opioid-free Multimodal Analgesia on Time to Trial of Void in Ambulatory Urogynecologic Surgeries
- Conditions
- Interventions
- First Posted Date
- 2024-04-23
- Last Posted Date
- 2024-04-23
- Lead Sponsor
- Northwell Health
- Target Recruit Count
- 70
- Registration Number
- NCT06379425
- Locations
- 🇺🇸
Northwell Health South Shore Surgery Center, Bay Shore, New York, United States
IV Dexmedetomidine vs Oral Gabapentin and Their Combination for Postoperative Analgesia in Cancer Patients Undergoing Modified Radical Mastectomy
- Conditions
- Interventions
- First Posted Date
- 2024-04-09
- Last Posted Date
- 2024-04-09
- Lead Sponsor
- National Cancer Institute, Egypt
- Target Recruit Count
- 90
- Registration Number
- NCT06354478
- Locations
- 🇪🇬
National Cancer Institute, Cairo, Egypt
Effect of Gabapentin on Kidney Function Following Laparoscopic Sleeve Gastrectomy(LSG)
- Conditions
- Interventions
- First Posted Date
- 2024-02-12
- Last Posted Date
- 2024-11-21
- Lead Sponsor
- Tanta University
- Target Recruit Count
- 60
- Registration Number
- NCT06254183
Pain Relief After Corneal Collagen Cross-Linking
- Conditions
- Interventions
- First Posted Date
- 2024-01-19
- Last Posted Date
- 2024-01-19
- Lead Sponsor
- Assaf-Harofeh Medical Center
- Target Recruit Count
- 51
- Registration Number
- NCT06212830
- Locations
- 🇮🇱
Shamir Medical Center (Assaf Harofeh), Be'er Ya'aqov, Israel
Preemptive Oral Gabapentin and Tramadol on Postoperative Pain After Knee Arthroscopy
- Conditions
- Interventions
- First Posted Date
- 2023-11-01
- Last Posted Date
- 2024-10-02
- Lead Sponsor
- Tanta University
- Target Recruit Count
- 50
- Registration Number
- NCT06112223
- Locations
- 🇪🇬
Tanta University, Tanta, El-Gharbia, Egypt
A Study Following Women in Menopause Treated With a Non-hormonal Therapy for Hot Flashes and Night Sweats
- Conditions
- Interventions
- Drug: FezolinetantDrug: ParoxetineDrug: GabapentinDrug: CitalopramDrug: ClonidineDrug: PregabalinDrug: EscitalopramDrug: DesvenlafaxineDrug: OxybutyninDrug: Any other non-hormonal pharmacologic therapy prescribed for the treatment of VMS not included in a category aboveDrug: VenlafaxineDrug: Any other SSRI/SNRI not already specified
- First Posted Date
- 2023-09-22
- Last Posted Date
- 2024-12-17
- Lead Sponsor
- Astellas Pharma Global Development, Inc.
- Target Recruit Count
- 1000
- Registration Number
- NCT06049797
- Locations
- 🇺🇸
Washington University School of Medicine, Saint Louis, Missouri, United States
🇺🇸SUNY Downstate Health Sciences University, Brooklyn, New York, United States
🇺🇸Mohawk Valley Health System - Womens Health Center, Utica, New York, United States
Multimodal Pain Package vs. Regular Formulation for Pain Management in Ambulatory Spinal Surgery
- Conditions
- Interventions
- First Posted Date
- 2023-07-28
- Last Posted Date
- 2024-06-21
- Lead Sponsor
- University of Miami
- Target Recruit Count
- 100
- Registration Number
- NCT05965492
- Locations
- 🇺🇸
university of Miami, Miami, Florida, United States
🇺🇸University of Miami, Miami, Florida, United States
Baclofen Versus Gabapentin in Preventing Postoperative Pain After Laparoscopic Sleeve Gastrectomy
- First Posted Date
- 2023-06-27
- Last Posted Date
- 2024-11-27
- Lead Sponsor
- Tanta University
- Target Recruit Count
- 100
- Registration Number
- NCT05921604
- Locations
- 🇪🇬
Gastrointestinal and Laparoscopic Surgery Unit, General Surgery Department, Tanta University Hospital, Tanta, Egypt, Tanta, Gharbiya, Egypt
Effect of Gabapentin on Sleep and Opioid Use Following Rotator Cuff Repair
- First Posted Date
- 2023-04-06
- Last Posted Date
- 2023-04-06
- Lead Sponsor
- Hughston Clinic
- Target Recruit Count
- 130
- Registration Number
- NCT05800847
Drug Development Updates
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