Amoxicillin

Generic Name
Amoxicillin
Brand Names
Amoxil, Augmentin, Clavulin, Moxatag, Omeclamox, Prevpac, Talicia, Voquezna 14 Day Dualpak 20;500, Voquezna 14 Day Triplepak 20;500;500
Drug Type
Small Molecule
Chemical Formula
C16H19N3O5S
CAS Number
26787-78-0
Unique Ingredient Identifier
9EM05410Q9
Background

Amoxicillin, or BRL-2333, is a penicillin G derivative first described in the literature in 1972. Amoxicillin has similar activity to penicillin and ampicillin, but leads to higher serum concentrations than ampicillin.

Amoxicillin was granted FDA approval on 18 January 1974.

Indication

Amoxicillin alone is indicated to treat susceptible bacterial infections of the ear, nose, throat, genitourinary tract, skin, skin structure, and lower respiratory tract. Amoxicillin is given with calvulanic acid to treat acute bacterial sinusitis, community acquired pneumonia, lower respiratory tract infections, acute bacterial otitis media, skin and skin s...

Associated Conditions
Acute Bacterial Sinusitis (ABS), Acute Otitis Media (AOM), Bacterial Infections, Community Acquired Pneumonia (CAP), Duodenal ulcer caused by helicobacter pylori, Genitourinary tract infection, Helicobacter Pylori Infection, Lower Respiratory Tract Infection (LRTI), Peptic Ulcer With H. Pylori Infection, Sinusitis, Skin and Subcutaneous Tissue Bacterial Infections, Urinary Tract Infection, Acute, uncomplicated Gonorrhea, Ear, nose, and throat infections
Associated Therapies
-
Clinical Trials
Related News

Clinical Efficacy of Amoxicillin Given Twice or Three Times a Day Among Children With Non-severe Pneumonia

Phase 4
Completed
Conditions
Community-acquired Pneumonia
Interventions
Drug: Amoxicillin
First Posted Date
2010-09-14
Last Posted Date
2011-07-20
Lead Sponsor
Federal University of Bahia
Target Recruit Count
820
Registration Number
NCT01200706
Locations
🇧🇷

Professor Hosannah de Oliveira Pediatric Center, Salvador, Bahia, Brazil

Community Case Management of the Severe Pneumonia With Oral Amoxicillin in Children 2-59 Months of Age

Not Applicable
Completed
Conditions
Severe Pneumonia
Interventions
Other: Referral to Health facility
Drug: Amoxicillin
First Posted Date
2010-09-01
Last Posted Date
2017-05-22
Lead Sponsor
Aga Khan University
Target Recruit Count
4070
Registration Number
NCT01192789
Locations
🇵🇰

Aga Khan University Research Office, Matiari, Matiari, Sidh, Pakistan

Treatment of Group A Beta Hemolytic Streptococcal Pharyngitis in Children in Low Resource Settings

First Posted Date
2010-07-05
Last Posted Date
2010-07-05
Lead Sponsor
Johns Hopkins University
Target Recruit Count
558
Registration Number
NCT01156740
Locations
🇭🇷

University Hospital for Infectious Diseases, Zagreb, Croatia

🇧🇷

Federal University of Rio de Janeiro, Rio de Janeiro, Brazil

🇪🇬

Cairo University, Cairo, Egypt

Efficacy and Safety Evaluation of Levofloxacin Triple Therapy for Helicobacter Pylori Eradication

Phase 3
Completed
Conditions
Helicobacter Pylori Infection
First Posted Date
2010-05-26
Last Posted Date
2011-08-09
Lead Sponsor
Deva Holding A.S.
Target Recruit Count
60
Registration Number
NCT01131026
Locations
🇹🇷

Erciyes University School of Medicine Hospital, Department of Internal Medicine and Gastroenterology, Kayseri, Turkey

Short Course of Amoxicillin for Erysipelas

Phase 4
Terminated
Conditions
Erysipelas
Interventions
Drug: Amoxicillin
First Posted Date
2010-01-29
Last Posted Date
2014-02-07
Lead Sponsor
Assistance Publique - Hôpitaux de Paris
Target Recruit Count
10
Registration Number
NCT01059123
Locations
🇫🇷

Hôpital Henri Mondor - Service de dermatologie, Créteil, Ile de France, France

Effectiveness of Oral Antibiotics in the Treatment of Severe Acute Malnutrition

Not Applicable
Completed
Conditions
Kwashiorkor
Marasmus
Interventions
Drug: Placebo
Drug: Amoxicillin
Drug: Cefdinir
First Posted Date
2009-10-23
Last Posted Date
2011-07-06
Lead Sponsor
Washington University School of Medicine
Target Recruit Count
2700
Registration Number
NCT01000298
Locations
🇲🇼

St. Louis Nutrition Project, Blantyre, Malawi

Cotrimoxazole Versus Amoxicillin in the Treatment of Community Acquired Pneumonia in Children Aged 2-59 Months

First Posted Date
2009-07-07
Last Posted Date
2009-07-07
Lead Sponsor
Makerere University
Target Recruit Count
505
Registration Number
NCT00933049
Locations
🇺🇬

Faculty of Medicine, Makerere University, Kampala, Uganda

Trial of Amoxicillin Compared With Placebo for Pneumonia in Children Aged 2-59 Months

Not Applicable
Completed
Conditions
Acute Respiratory Infections
Pneumonia
Interventions
Drug: Placebo
Drug: Amoxicillin
First Posted Date
2009-02-26
Last Posted Date
2009-02-26
Lead Sponsor
Pakistan Institute of Medical Sciences
Target Recruit Count
900
Registration Number
NCT00851487
Locations
🇵🇰

ARI Research Cell, Children Hospital, PIMS, Islamabad, Federal Capital, Pakistan

Evaluation of Inflammatory Symptoms Reduction With Amoxicillin + Ketoprofen in Acute Pharyngeal Tonsillitis in Pediatric Patients

First Posted Date
2008-12-01
Last Posted Date
2014-10-24
Lead Sponsor
Sanofi
Target Recruit Count
106
Registration Number
NCT00799838
Locations
🇧🇷

Sanofi-Aventis Administrative Office, Sao Paulo, Brazil

Amoxicillin Susceptibility of Oral Streptococci After a 3-Day or a 7-Day Amoxicillin Therapy

Phase 4
Terminated
Conditions
Odontogenic Infection
Interventions
Drug: Amoxicillin
First Posted Date
2008-10-01
Last Posted Date
2008-10-01
Lead Sponsor
Assistance Publique - Hôpitaux de Paris
Target Recruit Count
81
Registration Number
NCT00764062
Locations
🇫🇷

Assistance Publique - Hôpitaux de Paris, Paris, France

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