Amoxicillin

Generic Name: Amoxicillin

Brand Names: Amoxil, Augmentin, Clavulin, Moxatag, Omeclamox, Prevpac, Talicia, Voquezna 14 Day Dualpak 20;500, Voquezna 14 Day Triplepak 20;500;500

Drug Type: Small Molecule

Chemical Formula: C_₁₆H_₁₉N_₃O_₅S

CAS Number: 26787-78-0

Unique Ingredient Identifier: 9EM05410Q9

Background: Amoxicillin, or BRL-2333, is a penicillin G derivative first described in the literature in 1972. Amoxicillin has similar activity to penicillin and ampicillin, but leads to higher serum concentrations than ampicillin.

Amoxicillin was granted FDA approval on 18 January 1974.

Indication: Amoxicillin alone is indicated to treat susceptible bacterial infections of the ear, nose, throat, genitourinary tract, skin, skin structure, and lower respiratory tract. Amoxicillin is given with calvulanic acid to treat acute bacterial sinusitis, community acquired pneumonia, lower respiratory tract infections, acute bacterial otitis media, skin and skin s...

Associated Conditions: Acute Bacterial Sinusitis (ABS), Acute Otitis Media (AOM), Bacterial Infections, Community Acquired Pneumonia (CAP), Duodenal ulcer caused by helicobacter pylori, Genitourinary tract infection, Helicobacter Pylori Infection, Lower Respiratory Tract Infection (LRTI), Peptic Ulcer With H. Pylori Infection, Sinusitis, Skin and Subcutaneous Tissue Bacterial Infections, Urinary Tract Infection, Acute, uncomplicated Gonorrhea, Ear, nose, and throat infections

Associated Therapies: -

Clinical Trials

Indiaclen Short Course Amoxycillin Therapy for Pneumonia With Wheeze

Phase 3

Completed

Conditions: Non-Severe Pneumonia With Wheeze

First Posted Date: 2006-12-05

Last Posted Date: 2006-12-05

Lead Sponsor: King George's Medical University

Target Recruit Count: 2000

Registration Number: NCT00407394

Locations: 🇮🇳
King George's Medical University, Lucknow, UP, India

Efficacy Study of Pristinamycin Versus Amoxicillin to Treat Tonsillitis Induced by Streptococcus in Children

Phase 3

Completed

Conditions: Tonsillitis

Interventions: Drug: pristinamycin
Drug: amoxicillin

First Posted Date: 2006-10-29

Last Posted Date: 2009-03-17

Lead Sponsor: Sanofi

Target Recruit Count: 395

Registration Number: NCT00393744

Locations: 🇫🇷
Sanofi-Aventis, Paris, France

Treatment of Acute Sinusitis

Phase 4

Completed

Conditions: Acute Respiratory Infections
Acute Rhinosinusitis

Interventions: Drug: Acetaminophen
Drug: Amoxicillin
Drug: Dextromethorphan hydrobromide with guaifenesin
Drug: Guaifenesin
Drug: Pseudoephedrine Sustained Action
Drug: Saline spray (0.65%)

First Posted Date: 2006-09-18

Last Posted Date: 2012-12-28

Lead Sponsor: Washington University School of Medicine

Target Recruit Count: 172

Registration Number: NCT00377403

Locations: 🇺🇸
Washington University in St. Louis, St. Louis, Missouri, United States

Helicobacter - Lymphoma - Radiation Part I: Eradication, Part II: Radiation

Phase 3

Conditions: Lymphoma
Lymphoma, Non-Hodgkin

First Posted Date: 2005-09-12

Last Posted Date: 2007-03-26

Lead Sponsor: Technische Universität Dresden

Target Recruit Count: 200

Registration Number: NCT00154440

Locations: 🇩🇪
Institute for Pathology, Bayreuth, Bavaria, Germany
🇩🇪
Dept. for Radiation Therapy & Radiooncology, University Hospital, Germany, Saxonia, Germany
🇩🇪
Med. Dept. I, Gastroenterology, Dresden, Saxonia, Germany

Antibiotic Therapy in Treating Patients With Low Grade Gastric Lymphoma

Phase 2

Completed

Conditions: Lymphoma

First Posted Date: 2004-08-24

Last Posted Date: 2012-07-02

Lead Sponsor: European Organisation for Research and Treatment of Cancer - EORTC

Target Recruit Count: 96

Registration Number: NCT00003151

Locations: 🇬🇧
Clatterbridge Centre for Oncology NHS Trust, Merseyside, England, United Kingdom
🇬🇧
Royal United Hospital, Bath, England, United Kingdom
🇬🇧
Royal Free Hospital, Hampstead, London, England, United Kingdom

and more 19 locations

Antibiotic Therapy and Antacids in Patients With Malt Lymphoma of the Stomach

Phase 2

Completed

Conditions: Lymphoma

Interventions: Drug: Amoxicillin
Drug: Bismuth Subsalicylate
Drug: Clarithromycin
Drug: Metronidazole Hydrochloride
Drug: Omeprazole
Drug: Tetracycline Hydrochloride

First Posted Date: 2004-06-10

Last Posted Date: 2018-10-24

Lead Sponsor: M.D. Anderson Cancer Center

Target Recruit Count: 5

Registration Number: NCT00002682

Locations: 🇺🇸
University of Texas - MD Anderson Cancer Center, Houston, Texas, United States
🇺🇸
MD Anderson Cancer Center Orlando, Orlando, Florida, United States