Amoxicillin
- Generic Name
- Amoxicillin
- Brand Names
- Amoxil, Augmentin, Clavulin, Moxatag, Omeclamox, Prevpac, Talicia, Voquezna 14 Day Dualpak 20;500, Voquezna 14 Day Triplepak 20;500;500
- Drug Type
- Small Molecule
- Chemical Formula
- C16H19N3O5S
- CAS Number
- 26787-78-0
- Unique Ingredient Identifier
- 9EM05410Q9
- Background
Amoxicillin, or BRL-2333, is a penicillin G derivative first described in the literature in 1972. Amoxicillin has similar activity to penicillin and ampicillin, but leads to higher serum concentrations than ampicillin.
Amoxicillin was granted FDA approval on 18 January 1974.
- Indication
Amoxicillin alone is indicated to treat susceptible bacterial infections of the ear, nose, throat, genitourinary tract, skin, skin structure, and lower respiratory tract. Amoxicillin is given with calvulanic acid to treat acute bacterial sinusitis, community acquired pneumonia, lower respiratory tract infections, acute bacterial otitis media, skin and skin structure infections, and urinary tract infections. Amoxicillin is given with omeprazole in the treatment of Helicobacter pylori (H. pylori) infection.
Amoxicillin is used in combination with vonoprazan and clarithromycin as co-packaged triple therapy or in combination with vonoprazan as co-packaged dual therapy to treat H. pylori infection in adults.
- Associated Conditions
- Acute Bacterial Sinusitis (ABS), Acute Otitis Media (AOM), Bacterial Infections, Community Acquired Pneumonia (CAP), Duodenal ulcer caused by helicobacter pylori, Genitourinary tract infection, Helicobacter Pylori Infection, Lower Respiratory Tract Infection (LRTI), Peptic Ulcer With H. Pylori Infection, Sinusitis, Skin and Subcutaneous Tissue Bacterial Infections, Urinary Tract Infection, Acute, uncomplicated Gonorrhea, Ear, nose, and throat infections
Interactions Between Cranberry Juice and Antibiotics Used to Treat Urinary Tract Infections
- Conditions
- Urinary Tract Infections
- First Posted Date
- 2004-06-09
- Last Posted Date
- 2006-11-30
- Target Recruit Count
- 18
- Registration Number
- NCT00084201
- Locations
- 🇺🇸
University of Washington, Seattle, Washington, United States
Effect of Three Periodontal Therapies in Current Smokers and Non-Smokers
- Conditions
- PeriodontitisPeriodontal Diseases
- Interventions
- First Posted Date
- 2003-08-05
- Last Posted Date
- 2013-04-22
- Lead Sponsor
- The Forsyth Institute
- Target Recruit Count
- 146
- Registration Number
- NCT00066066
- Locations
- 🇺🇸
Department of Periodontology, Cambridge, Massachusetts, United States
Amoxicillin for the Treatment of Pediatric Autoimmune Disorders Associated With Streptococcal Infections
- Conditions
- Autoimmune DiseaseMental DisorderObsessive Compulsive DisorderStreptococcal InfectionTic Disorder
- First Posted Date
- 2002-12-10
- Last Posted Date
- 2008-03-04
- Lead Sponsor
- National Institute of Mental Health (NIMH)
- Target Recruit Count
- 30
- Registration Number
- NCT00001658
- Locations
- 🇺🇸
National Institute of Mental Health (NIMH), Bethesda, Maryland, United States
Acupuncture and Herbal Treatment of Chronic HIV Sinusitis
- Conditions
- HIV InfectionsSinusitis
- First Posted Date
- 2001-08-31
- Last Posted Date
- 2005-06-24
- Lead Sponsor
- Immune Enhancement Project
- Target Recruit Count
- 40
- Registration Number
- NCT00002149
- Locations
- 🇺🇸
Immune Enhancement Project, San Francisco, California, United States
Prospective Comparison of Ampicillin / Amoxicillin Versus Ceftriaxone for the Treatment of Salmonella Infections in AIDS Patients
- Conditions
- HIV InfectionsSalmonella Infections
- First Posted Date
- 2001-08-31
- Last Posted Date
- 2005-06-24
- Lead Sponsor
- University of Southern California
- Registration Number
- NCT00002052
- Locations
- 🇺🇸
Los Angeles County - USC Med Ctr, Los Angeles, California, United States
Drug Development Updates
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