Ropivacaine

Generic Name: Ropivacaine

Brand Names: Naropin

Drug Type: Small Molecule

Chemical Formula: C_₁₇H_₂₆N_₂O

CAS Number: 84057-95-4

Unique Ingredient Identifier: 7IO5LYA57N

Background: Ropivacaine is an aminoamide local anesthetic drug marketed by AstraZeneca under the trade name Naropin. It exists as a racemate of its S- and R-enantiomers, although the marketed form is supplied only as the purified S-enantiomer.

Indication: Ropivacaine is indicated in adult patients for the induction of regional or local anesthesia for surgery or acute pain management.

Associated Conditions: Acute Pain, Postoperative pain

Associated Therapies: Surgical anesthesia therapy

Clinical Trials

Continuous Pre-uterine Wound Infiltration Versus Intrathecal Morphine for Postoperative Analgesia After Cesarean Section

Phase 4

Conditions: Postoperative Pain

Interventions: Drug: Ropivacaine
Drug: Morphine

First Posted Date: 2014-10-31

Last Posted Date: 2014-10-31

Lead Sponsor: Central Hospital, Nancy, France

Target Recruit Count: 150

Registration Number: NCT02279628

Locations: 🇫🇷
Maternité Régionale Universitaire (MRU), Nancy, Lorraine, France

Comparison of Regimens MPIB, CIPCEA, PCEA

Phase 3

Active, not recruiting

Conditions: Breakthrough Pain

Interventions: Device: epidural delivery system
Drug: Ropivacaine
Drug: Fentanyl

First Posted Date: 2014-10-30

Last Posted Date: 2024-10-09

Lead Sponsor: KK Women's and Children's Hospital

Target Recruit Count: 839

Registration Number: NCT02278601

Locations: 🇸🇬
KK Women's and Children's Hospital, Singapore, Singapore

Effective Pain Management of Interscalene Blocks During Shoulder Surgery

Not Applicable

Completed

Conditions: Primary Osteoarthritis, Unspecified Shoulder

Interventions: Drug: Ropivacaine

First Posted Date: 2014-10-17

Last Posted Date: 2018-10-26

Lead Sponsor: TriHealth Inc.

Target Recruit Count: 76

Registration Number: NCT02267044

Locations: 🇺🇸
Good Samaritan Hospital, Cincinnati, Ohio, United States

Intra-Peritoneal Local Anaesthesia After Cytoreductive Surgery

Phase 3

Completed

Conditions: Pain

Interventions: Drug: Saline
Drug: Ropivacaine

First Posted Date: 2014-10-03

Last Posted Date: 2019-01-15

Lead Sponsor: Göteborg University

Target Recruit Count: 40

Registration Number: NCT02256228

Locations: 🇸🇪
Dept. of Gynecological Surgery and Anesthesia and Intensive Care, Sahlgrenska University Hospital, Goteborg, Sweden

Transmuscular Quadratus Lumborum Block for Laparoscopic Cholecystectomy

Not Applicable

Withdrawn

Conditions: Cholecystitis
Pain

Interventions: Drug: saline
Drug: Ropivacaine

First Posted Date: 2014-08-26

Last Posted Date: 2015-07-22

Lead Sponsor: Jens Borglum Neimann

Registration Number: NCT02225418

Locations: 🇩🇰
Bispebjerg Hospital, Copenhagen, Denmark

The Effect of Dexmedetomidine on Brachial Plexus Block for Shoulder Surgery

Phase 2

Completed

Conditions: Shoulder Pain
Nerve Pain

Interventions: Drug: Ropivacaine
Drug: Dexmedetomidine
Drug: Normal Saline

First Posted Date: 2014-08-25

Last Posted Date: 2017-11-06

Lead Sponsor: Women's College Hospital

Target Recruit Count: 99

Registration Number: NCT02225054

Locations: 🇨🇦
Women's College Hospital, Toronto, Ontario, Canada

Prospective Clinical Trial Comparing Infraclavicular Versus Axillary Approach to Brachial Plexus Block

Not Applicable

Conditions: Scaphoid Fractures
Distal Radius Fractures
Wrist Injury Arthrodesis

Interventions: Drug: Ropivacaine

First Posted Date: 2014-08-05

Last Posted Date: 2014-08-05

Lead Sponsor: Federal University of São Paulo

Target Recruit Count: 46

Registration Number: NCT02208245

Locations: 🇧🇷
Federal University of Sao Paulo - Hospital Sao Paulo, Sao Paulo, Brazil

Spinal Anaesthesia With Levobupivacaine 0.5% and Ropivacaine 0.75% for Lower Limb Orthopaedic Surgery

Phase 4

Completed

Conditions: Lower Limb Surgery

Interventions: Drug: Levobupivacaine
Drug: Ropivacaine

First Posted Date: 2014-07-28

Last Posted Date: 2015-01-21

Lead Sponsor: Aligarh Muslim University

Target Recruit Count: 60

Registration Number: NCT02201784

Locations: 🇮🇳
Jawaharlal Nehru medical college, AMU, Aligarh, Uttar Pradesh, India

Magnesium as Adjuvant for Sciatic Block

Not Applicable

Completed

Conditions: Hallux Valgus

Interventions: Drug: Ropivacaine
Drug: Magnesium Sulfate

First Posted Date: 2014-07-23

Last Posted Date: 2024-08-26

Lead Sponsor: Campus Bio-Medico University

Target Recruit Count: 60

Registration Number: NCT02198547

Locations: 🇮🇹
Campus Bio-Medico, Rome, Italy

Postoperative Analgesia After Caesarean Section Under ALR: TAP Block Versus Catheter Scar Infiltration

Phase 3

Conditions: Scheduled Caesarian Section

Interventions: Device: The infiltration continues catheter
Drug: Ropivacaine

First Posted Date: 2014-07-09

Last Posted Date: 2014-07-09

Lead Sponsor: Assistance Publique Hopitaux De Marseille

Target Recruit Count: 60

Registration Number: NCT02184559

Locations: 🇫🇷
Assistance Publique Hopitaux de Marseille, Marseille, France

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